Literature DB >> 28149122

Why scientists perform animal experiments, scientific or personal aim?

Burhan Mayir1, Uğur Doğan1, Tuna Bilecik1, Erdem Can Yardımcı1, Tuğrul Çakır1, Arif Aslaner1, Yeliz Akpınar Mayir1, Mehmet Tahir Oruç1.   

Abstract

OBJECTIVE: Although all animal studies are conducted in line with a specific purpose, we think that not all animal studies are performed for a scientific purpose but for personal curiosity or to fulfill a requirement. The aim of the present study is to reveal the purposes of experimental studies conducted on animals. MATHERIAL AND METHODS: We searched for experimental studies performed on rats in general surgery clinics via PubMed, and obtained the e-mail addresses of the corresponding authors for each study. Afterwards, we sent a 7-item questionnaire to the authors and awaited their responses.
RESULTS: Seventy-three (22.2%) of 329 authors responded to the questionnaire. Within these studies, 31 (42.5%) were conducted as part of a dissertation, while the remaining 19 (26.0%) were conducted to meet the academic promotion criteria. Only 23 (31.5%) were conducted for scientific purposes. The cost of 41% of those studies was higher than 2500 $.
CONCLUSION: As shown in this study, the main objective of carrying out animal studies in Turkey is usually to prepare a dissertation or to be entitled to academic promotion. Animal experiments must be planned and performed as scientific studies to support related clinical studies. Additionally, animal studies must have well-defined objectives and be carried out in line with scientific purposes that may lead to useful developments in medicine, rather than personal interests.

Entities:  

Keywords:  Animal experiment; ethics; experimental study; general surgery

Year:  2016        PMID: 28149122      PMCID: PMC5245717          DOI: 10.5152/UCD.2016.3196

Source DB:  PubMed          Journal:  Ulus Cerrahi Derg        ISSN: 1300-0705


  9 in total

Review 1.  Use of animals in experimental research: an ethical dilemma?

Authors:  V Baumans
Journal:  Gene Ther       Date:  2004-10       Impact factor: 5.250

2.  Estimates for worldwide laboratory animal use in 2005.

Authors:  Katy Taylor; Nicky Gordon; Gill Langley; Wendy Higgins
Journal:  Altern Lab Anim       Date:  2008-07       Impact factor: 1.303

3.  Animal experimentation--a personal view.

Authors:  Stanley N Gershoff
Journal:  Nutr Rev       Date:  2009-02       Impact factor: 7.110

4.  History, ethics, advantages and limitations of experimental models for hepatic ablation.

Authors:  Seok Ling Ong; Gianpiero Gravante; Matthew S Metcalfe; Ashley R Dennison
Journal:  World J Gastroenterol       Date:  2013-01-14       Impact factor: 5.742

5.  Ethical boundary-work in the animal research laboratory.

Authors:  Pru Hobson-West
Journal:  Sociology       Date:  2012-08

6.  Alternatives to animal testing: current status and future perspectives.

Authors:  Manfred Liebsch; Barbara Grune; Andrea Seiler; Daniel Butzke; Michael Oelgeschläger; Ralph Pirow; Sarah Adler; Christian Riebeling; Andreas Luch
Journal:  Arch Toxicol       Date:  2011-08       Impact factor: 5.153

7.  Publication bias in laboratory animal research: a survey on magnitude, drivers, consequences and potential solutions.

Authors:  Gerben ter Riet; Daniel A Korevaar; Marlies Leenaars; Peter J Sterk; Cornelis J F Van Noorden; Lex M Bouter; René Lutter; Ronald P Oude Elferink; Lotty Hooft
Journal:  PLoS One       Date:  2012-09-05       Impact factor: 3.240

8.  Regulations and ethical considerations in animal experiments: international laws and islamic perspectives.

Authors:  Mohammad Mehdi Naderi; Ali Sarvari; Alireza Milanifar; Sara Borjian Boroujeni; Mohammad Mehdi Akhondi
Journal:  Avicenna J Med Biotechnol       Date:  2012-07

Review 9.  They see a rat, we seek a cure for diseases: the current status of animal experimentation in medical practice.

Authors:  Elijah O Kehinde
Journal:  Med Princ Pract       Date:  2013-11-09       Impact factor: 1.927

  9 in total

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