Literature DB >> 28144675

Self-assembly of ultra-small micelles from amphiphilic lipopeptoids.

King Hang Aaron Lau1, Valeria Castelletto2, Thomas Kendall3, Jan Sefcik4, Ian W Hamley2, Mehedi Reza5, Janne Ruokolainen5.   

Abstract

Poly(N-substituted glycine) "peptoids" constitute a promising class of peptide-mimetic materials. We introduce the self-assembly of lipopeptoids into spherical micelles ca. 5 nm in diameter as well as larger assemblies by varying the peptoid sequence design. Our results point to design rules for the self-assembly of peptoid nanostructures, enabling the creation of stable, ultra-small peptidomimetic nanospheres.

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Year:  2017        PMID： 28144675     DOI： 10.1039/c6cc09888f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

Review 1.  Peptoid drug discovery and optimization via surface X-ray scattering.

Authors:  Konstantin Andreev; Michael W Martynowycz; David Gidalevitz
Journal:  Biopolymers       Date:  2019-03-20       Impact factor: 2.505

2.  Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on ESKAPE Bacterial Pathogens.

Authors:  Josefine Eilsø Nielsen; Morgan Ashley Alford; Deborah Bow Yue Yung; Natalia Molchanova; John A Fortkort; Jennifer S Lin; Gill Diamond; Robert E W Hancock; Håvard Jenssen; Daniel Pletzer; Reidar Lund; Annelise E Barron
Journal:  ACS Infect Dis       Date:  2022-02-17       Impact factor: 5.084

3.  Chain-End Modifications and Sequence Arrangements of Antimicrobial Peptoids for Mediating Activity and Nano-Assembly.

Authors:  Abshar Hasan; Varun Saxena; Valeria Castelletto; Georgina Zimbitas; Jani Seitsonen; Janne Ruokolainen; Lalit M Pandey; Jan Sefcik; Ian W Hamley; King Hang Aaron Lau
Journal:  Front Chem       Date:  2020-05-21       Impact factor: 5.221

Review 4.  Lipidation of Antimicrobial Peptides as a Design Strategy for Future Alternatives to Antibiotics.

Authors:  Taylor Rounds; Suzana K Straus
Journal:  Int J Mol Sci       Date:  2020-12-18       Impact factor: 5.923

5.  Self-Assembly of Minimal Peptoid Sequences.

Authors:  Valeria Castelletto; Jani Seitsonen; Kunal M Tewari; Abshar Hasan; Robert M Edkins; Janne Ruokolainen; Lalit M Pandey; Ian W Hamley; King Hang Aaron Lau
Journal:  ACS Macro Lett       Date:  2020-03-19       Impact factor: 6.903
  5 in total

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