| Literature DB >> 28134521 |
Feifei Liu1, Tao Yuan2, Wei Liu1, Hang Ma3, Navindra P Seeram3, Yuanyuan Li1, Li Xu1, Yu Mu1, Xueshi Huang1, Liya Li1.
Abstract
Fifteen new phloroglucinol derivatives, jamunones A-O (1-8 and 10-16, respectively), along with one known analogue spiralisone C (9), were isolated from Eugenia jambolana seeds. Their structures were elucidated by detailed nuclear magnetic resonance and mass spectrometry spectroscopic data interpretation. Compounds 1-9, 11, 12, and 14-16 inhibited protein tyrosine phosphatase 1B activity with IC50 values ranging from 0.42 to 3.2 μM.Entities:
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Year: 2017 PMID： 28134521 DOI： 10.1021/acs.jnatprod.6b01073
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050