| Literature DB >> 28134265 |
Peter Simmonds1, Mike J Adams, Mária Benkő2, Mya Breitbart3, J Rodney Brister4, Eric B Carstens5, Andrew J Davison6, Eric Delwart7,8, Alexander E Gorbalenya9,10, Balázs Harrach2, Roger Hull11, Andrew M Q King12, Eugene V Koonin4, Mart Krupovic13, Jens H Kuhn14, Elliot J Lefkowitz15, Max L Nibert16, Richard Orton6, Marilyn J Roossinck17, Sead Sabanadzovic18, Matthew B Sullivan19, Curtis A Suttle20,21, Robert B Tesh22, René A van der Vlugt23, Arvind Varsani24, F Murilo Zerbini25.
Abstract
The number and diversity of viral sequences that are identified in metagenomic data far exceeds that of experimentally characterized virus isolates. In a recent workshop, a panel of experts discussed the proposal that, with appropriate quality control, viruses that are known only from metagenomic data can, and should be, incorporated into the official classification scheme of the International Committee on Taxonomy of Viruses (ICTV). Although a taxonomy that is based on metagenomic sequence data alone represents a substantial departure from the traditional reliance on phenotypic properties, the development of a robust framework for sequence-based virus taxonomy is indispensable for the comprehensive characterization of the global virome. In this Consensus Statement article, we consider the rationale for why metagenomic sequence data should, and how it can, be incorporated into the ICTV taxonomy, and present proposals that have been endorsed by the Executive Committee of the ICTV.Mesh：
Year: 2017 PMID： 28134265 DOI： 10.1038/nrmicro.2016.177
Source DB: PubMed Journal: Nat Rev Microbiol ISSN： 1740-1526 Impact factor: 60.633