Literature DB >> 28133645

Selectively lighting up two-photon photodynamic activity in mitochondria with AIE-active iridium(iii) complexes.

Jiangping Liu1, Chengzhi Jin1, Bo Yuan1, Xingguo Liu2, Yu Chen1, Liangnian Ji1, Hui Chao1.   

Abstract

Herein a series of mitochondria-targeted AIE (aggregation-induced emission)-active Ir(iii) complexes were designed to selectively exert one-/two-photon photodynamic activities in mitochondria to address the issues which current PDT are confronted with (i.e., shallow penetration depth of routinely used irradiation; systematic toxicity associated with effective drug concentration; concentration-quenched photodynamic activity at the target, etc.).

Entities:  

Year:  2017        PMID： 28133645     DOI： 10.1039/c6cc10015e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

Review 1.  Phototherapy and optical waveguides for the treatment of infection.

Authors:  Dingbowen Wang; Michelle Laurel Kuzma; Xinyu Tan; Tong-Chuan He; Cheng Dong; Zhiwen Liu; Jian Yang
Journal:  Adv Drug Deliv Rev       Date:  2021-11-03       Impact factor: 15.470

Review 2.  Recent advances in noble metal complex based photodynamic therapy.

Authors:  Yanping Wu; Shumeng Li; Yuncong Chen; Weijiang He; Zijian Guo
Journal:  Chem Sci       Date:  2022-04-01       Impact factor: 9.969

3.  Hyaluronic Acid Grafted Nanoparticles of a Platinum(II)-Silicon(IV) Phthalocyanine Conjugate for Tumor and Mitochondria-Targeted Photodynamic Therapy in Red Light.

Authors:  Koushambi Mitra; Montserrat Samso; Charles E Lyons; Matthew C T Hartman
Journal:  J Mater Chem B       Date:  2018-10-24       Impact factor: 6.331

4.  A Cyclodextrin-Hosted Ir(III) Complex for Ratiometric Mapping of Tumor Hypoxia In Vivo.

Authors:  Peng Xiao; Chunyan Liu; Tiancong Ma; Xiuhong Lu; Lihong Jing; Yi Hou; Peisen Zhang; Gang Huang; Mingyuan Gao
Journal:  Adv Sci (Weinh)       Date:  2021-02-05       Impact factor: 16.806

5.  Multifunctional AIE iridium (III) photosensitizer nanoparticles for two-photon-activated imaging and mitochondria targeting photodynamic therapy.

Authors:  Xuzi Cai; Kang-Nan Wang; Wen Ma; Yuanyuan Yang; Gui Chen; Huijiao Fu; Chunhui Cui; Zhiqiang Yu; Xuefeng Wang
Journal:  J Nanobiotechnology       Date:  2021-08-23       Impact factor: 10.435

Review 6.  Improving the Phototherapeutic Efficiencies of Molecular and Nanoscale Materials by Targeting Mitochondria.

Authors:  Fengming Lin; Yan-Wen Bao; Fu-Gen Wu
Journal:  Molecules       Date:  2018-11-18       Impact factor: 4.411

7.  Pyridazine-bridged cationic diiridium complexes as potential dual-mode bioimaging probes.

Authors:  Ruth E Daniels; Luke K McKenzie; Jonathan R Shewring; Julia A Weinstein; Valery N Kozhevnikov; Helen E Bryant
Journal:  RSC Adv       Date:  2018-03-06       Impact factor: 3.361
  7 in total

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