| Literature DB >> 28126664 |
Nathieli Bianchin Bottari1, Leonardo Quintana Soares Lopes2, Kauana Pizzuti2, Camilla Filippi Dos Santos Alves3, Marcos Saldanha Corrêa2, Leandro Perger Bolzan2, Adriana Zago4, Rodrigo de Almeida Vaucher2, Aline Augusti Boligon5, Janice Luehring Giongo6, Matheus Dellaméa Baldissera3, Roberto Christ Vianna Santos3.
Abstract
Carya illinoensis is a widespread species, belonging to the Juglandaceae family, commonly known as Pecan. Popularly, the leaves have been used in the treatment of smoking as a hypoglycemic, cleansing, astringent, keratolytic, antioxidant, and antimicrobial agent. The following research aimed to identify for the first time the phytochemical compounds present in the leaves of C. illinoensis and carry out the determination of antimicrobial activity of aqueous and ethanolic extracts. The antimicrobial activity was tested against 20 microorganisms by determining the minimum inhibitory concentration (MIC). Phenolic acids (gallic acid and ellagic acid), flavonoids (rutin), and tannins (catechins and epicatechins) were identified by HPLC-DAD and may be partially responsible for the antimicrobial activity against Gram-positive, Gram-negative, and yeast. The results showed MIC values between 25 mg/mL and 0.78 mg/mL. The extracts were also able to inhibit the production of germ tubes by Candida albicans.Entities:
Keywords: Antimicrobial activity; C. illinoensis; Flavonoids; Germinal tube; Phenols
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Year: 2017 PMID: 28126664 DOI: 10.1016/j.micpath.2017.01.037
Source DB: PubMed Journal: Microb Pathog ISSN: 0882-4010 Impact factor: 3.738