Literature DB >> 28122484

Anatomic Peculiarities of Pig and Human Liver.

Andriy Nykonenko1, Petr Vávra, Pavel Zonča.   

Abstract

Many investigations on surgical methods and medical treatment are currently done on pigs. This is possible because the pig is sufficiently close genetically to humans. In recent years, progress in liver surgery has opened new possibilities in surgical treatment of liver diseases. Because the methods are relatively novel, various improvements are still needed, and it is thus helpful to conduct experimental surgeries on pig livers. We reviewed the literature to compare the anatomic and functional features of pig and human livers, information that will be of great importance for improving surgical techniques. During the literature review, we used various sources, such as PubMed, Scopus, and veterinary journals. Our results were summarized in diagrams to facilitate understanding of the vascular structure and biliary systems. We conclude that, although the shapes of the human and pig livers are quite different, the pig liver is divided into the same number of segments as the human liver, which also shows a common structure of the vascular system. Thus, with the anatomic and structural features of the pig liver taken into account, this animal model can be used in experimental hepatic surgery.

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Year:  2017        PMID: 28122484

Source DB:  PubMed          Journal:  Exp Clin Transplant        ISSN: 1304-0855            Impact factor:   0.945


  11 in total

1.  Assessment of Plasma Coagulation on Liver Tissue in a Large Animal Model In Vivo.

Authors:  Tim R Glowka; Pascal Paschenda; Michael Czaplik; Jörg C Kalff; René H Tolba
Journal:  J Vis Exp       Date:  2018-08-04       Impact factor: 1.355

2.  Bevacizumab Does Not Inhibit the Formation of Liver Vessels and Liver Regeneration Following Major Hepatectomy: A Large Animal Model Study.

Authors:  Ondrej Troup; Adam Skalicky; Lucie Vistejnova; Pavel Klein; Anna Maleckova; Blanka Florova; Tomas Malkus; Jiri Molacek; Vladislav Treska; Miroslav Kriz; Jan Zeman; Tomas Skalicky
Journal:  In Vivo       Date:  2022 May-Jun       Impact factor: 2.406

3.  In Vivo Models for the Performance and Safety of BAT-90, a Novel 90-Yttrium-based Internal Radiotherapy Platform.

Authors:  Antonino Amato; Gordon McVie; Giovanni Paganelli; Pier Luigi Carriero; Roberto Cianni; Giuseppe Maria Ettorre
Journal:  In Vivo       Date:  2022 Sep-Oct       Impact factor: 2.406

4.  Utilization of dielectric properties for assessment of liver ischemia-reperfusion injury in vivo and during machine perfusion.

Authors:  Jie Hou; Olav Magnus Ivar Liavåg; Ida Høy Færden; Ørjan Grøttem Martinsen; Tor Inge Tønnessen; Pål-Dag Line; Morten Hagness; Jan Olav Høgetveit; Søren Erik Pischke; Runar Strand-Amundsen
Journal:  Sci Rep       Date:  2022-07-01       Impact factor: 4.996

5.  Stimulation of the hepatoportal nerve plexus with focused ultrasound restores glucose homoeostasis in diabetic mice, rats and swine.

Authors:  Victoria Cotero; John Graf; Hiromi Miwa; Zall Hirschstein; Khaled Qanud; Tomás S Huerta; Ningwen Tai; Yuyan Ding; Kevin Jimenez-Cowell; Jacquelyn N Tomaio; Weiguo Song; Alex Devarajan; Tea Tsaava; Radhika Madhavan; Kirk Wallace; Evelina Loghin; Christine Morton; Ying Fan; Tzu-Jen Kao; Kainat Akhtar; Meghana Damaraju; Linda Barenboim; Teresa Maietta; Jeffrey Ashe; Kevin J Tracey; Thomas R Coleman; Dino Di Carlo; Damian Shin; Stavros Zanos; Sangeeta S Chavan; Raimund I Herzog; Chris Puleo
Journal:  Nat Biomed Eng       Date:  2022-03-31       Impact factor: 29.234

6.  Radiological findings of porcine liver after electrochemotherapy with bleomycin.

Authors:  Maja Brloznik; Nina Boc; Gregor Sersa; Jan Zmuc; Gorana Gasljevic; Alenka Seliskar; Rok Dezman; Ibrahim Edhemovic; Nina Milevoj; Tanja Plavec; Vladimira Erjavec; Darja Pavlin; Masa Bosnjak; Erik Brecelj; Ursa Lampreht Tratar; Bor Kos; Jani Izlakar; Marina Stukelj; Damijan Miklavcic; Maja Cemazar
Journal:  Radiol Oncol       Date:  2019-10-10       Impact factor: 2.991

Review 7.  Alcohol Induced Brain and Liver Damage: Advantages of a Porcine Alcohol Use Disorder Model.

Authors:  Soo K Shin; Erin E Kaiser; Franklin D West
Journal:  Front Physiol       Date:  2021-01-07       Impact factor: 4.566

8.  Fluoroless intravascular ultrasound image-guided liver navigation in porcine models.

Authors:  Takeshi Urade; Juan Manuel Verde; Alain García Vázquez; Konstanze Gunzert; Patrick Pessaux; Jacques Marescaux; Mariano Eduardo Giménez
Journal:  BMC Gastroenterol       Date:  2021-01-09       Impact factor: 3.067

Review 9.  Liver organoids in domestic animals: an expected promise for metabolic studies.

Authors:  Camille Baquerre; Guillaume Montillet; Bertrand Pain
Journal:  Vet Res       Date:  2021-03-18       Impact factor: 3.683

10.  Preclinical models of acute liver failure: a comprehensive review.

Authors:  Joshua Hefler; Braulio A Marfil-Garza; Rena L Pawlick; Darren H Freed; Constantine J Karvellas; David L Bigam; A M James Shapiro
Journal:  PeerJ       Date:  2021-12-09       Impact factor: 2.984

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