Literature DB >> 28112838

Biomimetic Engineering Using Cancer Cell Membranes for Designing Compartmentalized Nanoreactors with Organelle-Like Functions.

Vimalkumar Balasubramanian1, Alexandra Correia1, Hongbo Zhang1,2, Flavia Fontana1, Ermei Mäkilä3, Jarno Salonen3, Jouni Hirvonen1, Hélder A Santos1.   

Abstract

A new biomimetic nanoreactor design is presented based on cancer cell membrane material in combination with porous silicon nanoparticles. This cellular nanoreactor features a biocompartment enclosed by a cell membrane and readily integrated with cells and supplementing the cellular functions under oxidative stress. The study demonstrates the impact of the nanoreactors on improving cellular functions with a potential to serve as artificial organelles.
© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  artificial organelles; biocompartmentalization; biomimetic materials; nanoreactors; porous silicon nanoparticles

Mesh：

Year:  2017        PMID： 28112838     DOI： 10.1002/adma.201605375

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  10 in total

1.  A Porous Au@Rh Bimetallic Core-Shell Nanostructure as an H2 O2 -Driven Oxygenerator to Alleviate Tumor Hypoxia for Simultaneous Bimodal Imaging and Enhanced Photodynamic Therapy.

Authors:  Jinping Wang; Jingyu Sun; Wei Hu; Yuhao Wang; Tsengming Chou; Beilu Zhang; Qiang Zhang; Lei Ren; Hongjun Wang
Journal:  Adv Mater       Date:  2020-04-24       Impact factor: 30.849

2.  Nanoreactors based on DNAzyme-functionalized magnetic nanoparticles activated by magnetic field.

Authors:  Saira F Bakshi; Nataliia Guz; Andrey Zakharchenko; Han Deng; Alexei V Tumanov; Craig D Woodworth; Sergiy Minko; Dmitry M Kolpashchikov; Evgeny Katz
Journal:  Nanoscale       Date:  2018-01-18       Impact factor: 7.790

3.  Cell Membrane-Based Nanoreactor To Mimic the Bio-Compartmentalization Strategy of a Cell.

Authors:  Vimalkumar Balasubramanian; Andrea Poillucci; Alexandra Correia; Hongbo Zhang; Christian Celia; Hélder A Santos
Journal:  ACS Biomater Sci Eng       Date:  2018-02-15

4.  Impact of Pore Size and Surface Chemistry of Porous Silicon Particles and Structure of Phospholipids on Their Interactions.

Authors:  Dongfei Liu; Katriina Lipponen; Peng Quan; Xiaocao Wan; Hongbo Zhang; Ermei Mäkilä; Jarno Salonen; Risto Kostiainen; Jouni Hirvonen; Tapio Kotiaho; Hélder A Santos
Journal:  ACS Biomater Sci Eng       Date:  2018-06-14

5.  Self-activated in vivo therapeutic cascade of erythrocyte membrane-cloaked iron-mineralized enzymes.

Authors:  Wen Liu; Miao-Liang Ruan; Lamei Liu; Xin Ji; Yandong Ma; Pengfei Yuan; Guoheng Tang; Hongsheng Lin; Jian Dai; Wei Xue
Journal:  Theranostics       Date:  2020-01-12       Impact factor: 11.556

Review 6.  Research Progress of Cell Membrane Biomimetic Nanoparticles for Tumor Therapy.

Authors:  Xuefen Zhao; Chao Yan
Journal:  Nanoscale Res Lett       Date:  2022-03-22       Impact factor: 5.418

7.  Aldehyde N,N-dimethylhydrazone-based fluorescent substrate for peroxidase-mediated assays.

Authors:  Soyeon Yoo; Sudeok Kim; Sangyeon Jeon; Min Su Han
Journal:  RSC Adv       Date:  2022-03-21       Impact factor: 3.361

8.  Hybrid red blood cell membrane coated porous silicon nanoparticles functionalized with cancer antigen induce depletion of T cells.

Authors:  Antti Rahikkala; Flavia Fontana; Tomás Bauleth-Ramos; Alexandra Correia; Marianna Kemell; Jani Seitsonen; Ermei Mäkilä; Bruno Sarmento; Jarno Salonen; Janne Ruokolainen; Jouni Hirvonen; Hélder A Santos
Journal:  RSC Adv       Date:  2020-09-23       Impact factor: 4.036

9.  Biomimetic artificial organelles with in vitro and in vivo activity triggered by reduction in microenvironment.

Authors:  T Einfalt; D Witzigmann; C Edlinger; S Sieber; R Goers; A Najer; M Spulber; O Onaca-Fischer; J Huwyler; C G Palivan
Journal:  Nat Commun       Date:  2018-03-19       Impact factor: 14.919

10.  Hyperthermia-Triggered On-Demand Biomimetic Nanocarriers for Synergetic Photothermal and Chemotherapy.

Authors:  Junbin Gao; Fei Wang; Shuanghu Wang; Lu Liu; Kun Liu; Yicheng Ye; Zhen Wang; Hong Wang; Bin Chen; Jiamiao Jiang; Juanfeng Ou; Jan C M van Hest; Fei Peng; Yingfeng Tu
Journal:  Adv Sci (Weinh)       Date:  2020-04-20       Impact factor: 16.806
  10 in total

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