Bo Li1, Hao Li2, Hanjing Kong3, Li Dong4, Jue Zhang5, Jing Fang5. 1. Center Laboratory, The First Hospital of Nanchang City, 330008 Nanchang, PR China; Department of Radiology, The Third Affiliated Hospital of Nanchang University, 330008 Nanchang, PR China. 2. Department of Radiology, University of Cambridge, CB2 0QQ Cambridge, UK. 3. Academy for Advanced Interdisciplinary Studies, Peking University, 100871 Beijing, PR China. 4. Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, 100029 Beijing, PR China. Electronic address: lidongmd@163.com. 5. Academy for Advanced Interdisciplinary Studies, Peking University, 100871 Beijing, PR China; College of Engineering, Peking University, 100871 Beijing, PR China.
Abstract
OBJECTIVE: In this study, we sought to demonstrate the blood suppression performance, image quality and morphological measurements for compressed sensing (CS) based simultaneous 3D black- and gray-blood imaging sequence (CS-siBLAG) in carotid vessel wall MR imaging. MATERIALS AND METHODS: Seven healthy volunteers and five patients were recruited. Healthy subjects underwent five CS-siBLAG scans with 1, 2, 3, 4 and 5-fold accelerations. Signal-to-tissue ratio (STR) and contrast-to-tissue ratio (CTR) were computed as the measures of flowing signal suppression performance and the image quality for black-blood imaging of the technique. Vessel lumen area (LA) and wall area (WA) were compared between fully sampled acquisition and each accelerated acquisition. Patients underwent three CS-siBLAG scans with 1, 3 and 5-fold accelerations as well as a 3D time of flight (3D TOF) scan. Two radiologists reviewed the under-sampled black- and gray-blood image quality. RESULTS: STR and CTR values obtained with 2 to 5-fold accelerations were not significantly different from those with full acquisition. LA and WA measured at 2×, 3×, 4× and 5× were all highly correlated to the corresponding values at 1×. For patients imaging, two radiologists both found that the dual-contrast images at 3× acceleration exhibited comparable image quality to that of the fully sampled acquisition, and that the images at 5× exhibited slightly blurred vessel wall and outer vessel wall boundaries. CONCLUSION: By combining the CS under-sampling pattern and reconstruction, pseudo-centric phase encoding order and dual blood contrast sequences, this technique provides spatially registered black- and gray-blood images and excellent visualization for vessel wall imaging and gray-blood imaging in a short scan time.
OBJECTIVE: In this study, we sought to demonstrate the blood suppression performance, image quality and morphological measurements for compressed sensing (CS) based simultaneous 3D black- and gray-blood imaging sequence (CS-siBLAG) in carotid vessel wall MR imaging. MATERIALS AND METHODS: Seven healthy volunteers and five patients were recruited. Healthy subjects underwent five CS-siBLAG scans with 1, 2, 3, 4 and 5-fold accelerations. Signal-to-tissue ratio (STR) and contrast-to-tissue ratio (CTR) were computed as the measures of flowing signal suppression performance and the image quality for black-blood imaging of the technique. Vessel lumen area (LA) and wall area (WA) were compared between fully sampled acquisition and each accelerated acquisition. Patients underwent three CS-siBLAG scans with 1, 3 and 5-fold accelerations as well as a 3D time of flight (3D TOF) scan. Two radiologists reviewed the under-sampled black- and gray-blood image quality. RESULTS: STR and CTR values obtained with 2 to 5-fold accelerations were not significantly different from those with full acquisition. LA and WA measured at 2×, 3×, 4× and 5× were all highly correlated to the corresponding values at 1×. For patients imaging, two radiologists both found that the dual-contrast images at 3× acceleration exhibited comparable image quality to that of the fully sampled acquisition, and that the images at 5× exhibited slightly blurred vessel wall and outer vessel wall boundaries. CONCLUSION: By combining the CS under-sampling pattern and reconstruction, pseudo-centric phase encoding order and dual blood contrast sequences, this technique provides spatially registered black- and gray-blood images and excellent visualization for vessel wall imaging and gray-blood imaging in a short scan time.
Authors: Mikell Yuhasz; Michael J Hoch; Mari Hagiwara; Mary T Bruno; James S Babb; Esther Raithel; Christoph Forman; Abbas Anwar; J Thomas Roland; Timothy M Shepherd Journal: Invest Radiol Date: 2018-12 Impact factor: 6.016
Authors: Jianmin Yuan; Ammara Usman; Scott A Reid; Kevin F King; Andrew J Patterson; Jonathan H Gillard; Martin J Graves Journal: MAGMA Date: 2017-06-26 Impact factor: 2.310