Literature DB >> 28106908

The aspirin story - from willow to wonder drug.

Michael J R Desborough1,2, David M Keeling3.   

Abstract

The story of the discovery of aspirin stretches back more than 3500 years to when bark from the willow tree was used as a pain reliever and antipyretic. It involves an Oxfordshire clergyman, scientists at a German dye manufacturer, a Nobel Prize-winning discovery and a series of pivotal clinical trials. Aspirin is now the most commonly used drug in the world. Its role in preventing cardiovascular and cerebrovascular disease has been revolutionary and one of the biggest pharmaceutical success stories of the last century.
© 2017 John Wiley & Sons Ltd.

Entities:  

Keywords:  acetylsalicylic acid; antiplatelet agent; aspirin; history; willow

Mesh:

Substances:

Year:  2017        PMID: 28106908     DOI: 10.1111/bjh.14520

Source DB:  PubMed          Journal:  Br J Haematol        ISSN: 0007-1048            Impact factor:   6.998


  42 in total

1.  Aspirin as a Potential Geroprotector: Experimental Data and Clinical Evidence.

Authors:  Oleh Lushchak; Veronika Piskovatska; Olha Strilbytska; Iryna Kindrat; Nadya Stefanyshyn; Alexander Koliada; Volodymyr Bubalo; Kenneth B Storey; Alexander Vaiserman
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

Review 2.  Therapeutic targeting of oncogenic transcription factors by natural products in eye cancer.

Authors:  Michelle G Zhang; John Y Lee; Ryan A Gallo; Wensi Tao; David Tse; Ravi Doddapaneni; Daniel Pelaez
Journal:  Pharmacol Res       Date:  2017-12-02       Impact factor: 7.658

Review 3.  Natural Products and HIV/AIDS.

Authors:  Daniele C Cary; B Matija Peterlin
Journal:  AIDS Res Hum Retroviruses       Date:  2018-01-10       Impact factor: 2.205

Review 4.  Aspirin in Primary Prevention of Cardiovascular Events.

Authors:  Deepa Soodi; Jeffrey J VanWormer; Shereif H Rezkalla
Journal:  Clin Med Res       Date:  2020-06-24

5.  Alleviating Aspirin-Induced Gastric Injury by Binding Aspirin to β-Lactoglobulin.

Authors:  Jin Chen; Min Gong; Zhuo Huang; Fang Wang; Yajing Wang; Zuquan Hu; Zhu Zeng; Yun Wang
Journal:  Drug Des Devel Ther       Date:  2022-03-01       Impact factor: 4.162

6.  KCNQ5 activation by tannins mediates vasorelaxant effects of barks used in Native American botanical medicine.

Authors:  Rían W Manville; Kaitlyn E Redford; Jennifer van der Horst; Derk J Hogenkamp; Thomas A Jepps; Geoffrey W Abbott
Journal:  FASEB J       Date:  2022-09       Impact factor: 5.834

7.  Berberine chloride suppresses non-small cell lung cancer by deregulating Sin3A/TOP2B pathway in vitro and in vivo.

Authors:  Jian Chen; Xiaofei Huang; Cheng Tao; Li Wang; Zide Chen; Xinping Li; Qiang Zeng; Min Ma; Ren Zhang; Zhengzhi Wu
Journal:  Cancer Chemother Pharmacol       Date:  2020-06-30       Impact factor: 3.333

Review 8.  Topical delivery of salicylates.

Authors:  Soo Chin Yeoh; Choon Fu Goh
Journal:  Drug Deliv Transl Res       Date:  2021-04-28       Impact factor: 4.617

Review 9.  Adaptive Membrane Fluidity Modulation: A Feedback Regulated Homeostatic System Hiding in Plain Sight.

Authors:  Elzbieta Izbicka; Robert T Streeper
Journal:  In Vivo       Date:  2021 Nov-Dec       Impact factor: 2.155

10.  Antiplatelet properties of Pim kinase inhibition are mediated through disruption of thromboxane A2 receptor signaling.

Authors:  Amanda J Unsworth; Alexander P Bye; Tanya Sage; Renato S Gaspar; Nathan Eaton; Caleb Drew; Alexander Stainer; Neline Kriek; Peter J Volberding; James L Hutchinson; Ryan Riley; Sarah Jones; Stuart J Mundell; Weiguo Cui; Hervé Falet; Jonathan M Gibbins
Journal:  Haematologica       Date:  2021-07-01       Impact factor: 9.941

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