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Literature DB >> 29226706

Natural Products and HIV/AIDS.

Daniele C Cary^1,2, B Matija Peterlin^1,2.

Abstract

The study of natural products in biomedical research is not a modern concept. Many of the most successful medical therapeutics are derived from natural products, including those studied in the field of HIV/AIDS. Biomedical research has a rich history of discovery based on screens of medicinal herbs and traditional medicine practices. Compounds derived from natural products, which repress HIV and those that activate latent HIV, have been reported. It is important to remember the tradition in medical research to derive therapies based on these natural products and to overcome the negative perception of natural products as an "alternative medicine."

Entities: Disease

Keywords: AIDS; HIV; HIV reactivation; HIV suppression; natural products

Mesh：

Substances：

Year: 2018 PMID： 29226706 PMCID： PMC5771529 DOI： 10.1089/AID.2017.0232

Source DB: PubMed Journal: AIDS Res Hum Retroviruses ISSN： 0889-2229 Impact factor: 2.205

72 in total

1. Kuwanon-L as a New Allosteric HIV-1 Integrase Inhibitor: Molecular Modeling and Biological Evaluation.

Authors: Francesca Esposito; Cristina Tintori; Riccardo Martini; Frauke Christ; Zeger Debyser; Roberto Ferrarese; Gianluigi Cabiddu; Angela Corona; Elisa Rita Ceresola; Andrea Calcaterra; Valentina Iovine; Bruno Botta; Massimo Clementi; Filippo Canducci; Maurizio Botta; Enzo Tramontano
Journal: Chembiochem Date: 2015-10-26 Impact factor: 3.164

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Journal: Proc Natl Acad Sci U S A Date: 1997-11-25 Impact factor: 11.205

Review 4. Paclitaxel (Taxol): a success story with valuable lessons for natural product drug discovery and development.

Authors: G M Cragg
Journal: Med Res Rev Date: 1998-09 Impact factor: 12.944

5. Bioactivity-guided isolation of antiproliferative diterpenoids from Euphorbia kansui.

Authors: Hong-Ying Wang; Jun-Song Wang; Dan-Dan Wei; Xiao-Bing Wang; Jun Luo; Ming-Hua Yang; Ling-Yi Kong
Journal: Phytother Res Date: 2011-11-14 Impact factor: 5.878

6. Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein.

Authors: Koen Bartholomeeusen; Yanhui Xiang; Koh Fujinaga; B Matija Peterlin
Journal: J Biol Chem Date: 2012-09-05 Impact factor: 5.157

Review 7. Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria.

Authors: Jane Achan; Ambrose O Talisuna; Annette Erhart; Adoke Yeka; James K Tibenderana; Frederick N Baliraine; Philip J Rosenthal; Umberto D'Alessandro
Journal: Malar J Date: 2011-05-24 Impact factor: 2.979

Review 8. Cocoa polyphenols and inflammatory markers of cardiovascular disease.

Authors: Nasiruddin Khan; Olha Khymenets; Mireia Urpí-Sardà; Sara Tulipani; Mar Garcia-Aloy; María Monagas; Ximena Mora-Cubillos; Rafael Llorach; Cristina Andres-Lacueva
Journal: Nutrients Date: 2014-02-21 Impact factor: 5.717

9. Reactivation of HIV-1 from Latency by an Ingenol Derivative from Euphorbia Kansui.

Authors: Pengfei Wang; Panpan Lu; Xiying Qu; Yinzhong Shen; Hanxian Zeng; Xiaoli Zhu; Yuqi Zhu; Xian Li; Hao Wu; Jianqing Xu; Hongzhou Lu; Zhongjun Ma; Huanzhang Zhu
Journal: Sci Rep Date: 2017-08-25 Impact factor: 4.379

10. Long-Term Survival of AIDS Patients Treated with Only Traditional Chinese Medicine.

Authors: Yifei Wang; Fujun Jin; Qiaoli Wang; Zucai Suo
Journal: AIDS Res Hum Retroviruses Date: 2017-01-31 Impact factor: 2.205

11 in total

Review 1. Insights Into Persistent HIV-1 Infection and Functional Cure: Novel Capabilities and Strategies.

Authors: Tram M Ta; Sajjaf Malik; Elizabeth M Anderson; Amber D Jones; Jocelyn Perchik; Maryann Freylikh; Luca Sardo; Zackary A Klase; Taisuke Izumi
Journal: Front Microbiol Date: 2022-04-27 Impact factor: 6.064

2. Identification of Aristolactam Derivatives That Act as Inhibitors of Human Immunodeficiency Virus Type 1 Infection and Replication by Targeting Tat-Mediated Viral Transcription.

Authors: YoungHyun Shin; Chul Min Park; Hong Gi Kim; Dong-Eun Kim; Min Suk Choi; Jeong-Ah Kim; Byeong-Sun Choi; Cheol-Hee Yoon
Journal: Virol Sin Date: 2020-08-10 Impact factor: 4.327

3. Identification of Novel HIV-1 Latency-Reversing Agents from a Library of Marine Natural Products.

Authors: Khumoekae Richard; David E Williams; E Dilip de Silva; Mark A Brockman; Zabrina L Brumme; Raymond J Andersen; Ian Tietjen
Journal: Viruses Date: 2018-06-27 Impact factor: 5.048

4. Procyanidin trimer C1 reactivates latent HIV as a triple combination therapy with kansui and JQ1.

Authors: Daniele C Cary; B Matija Peterlin
Journal: PLoS One Date: 2018-11-26 Impact factor: 3.240

Review 5. Structure-Activity-Relationship and Mechanistic Insights for Anti-HIV Natural Products.

Authors: Ramandeep Kaur; Pooja Sharma; Girish K Gupta; Fidele Ntie-Kang; Dinesh Kumar
Journal: Molecules Date: 2020-04-29 Impact factor: 4.411

Review 6. Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities.

Authors: Lu Luo; Jun Yang; Cheng Wang; Jie Wu; Yafang Li; Xu Zhang; Hui Li; Hui Zhang; Yumei Zhou; Aiping Lu; Shilin Chen
Journal: Sci China Life Sci Date: 2021-10-21 Impact factor: 10.372

7. Voacanga globosa Spirobisindole Alkaloids Exert Antiviral Activity in HIV Latently Infected Cell Lines by Targeting the NF-kB Cascade: In Vitro and In Silico Investigations.

Authors: Ma Sheila M de Jesus; Allan Patrick G Macabeo; John Donnie A Ramos; Von Novi O de Leon; Kaori Asamitsu; Takashi Okamoto
Journal: Molecules Date: 2022-02-05 Impact factor: 4.411