Jae-Hwan Choi1, Min-Gyu Park1, Seo Young Choi1, Kyung-Pil Park1, Seung Kug Baik1, Ji-Soo Kim1, Kwang-Dong Choi2. 1. From the Department of Neurology (J.-H.C., M.-G.P., K.-P.P.) and Radiology (S.K.B.), Pusan National University School of Medicine, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, South Korea; Department of Neurology, Seoul National University Bundang Hospital, South Korea (S.Y.C., J.-S.K.); and Department of Neurology, Pusan National University Hospital, Pusan National University School of Medicine and Biomedical Research Institute, South Korea (K.-D.C.). 2. From the Department of Neurology (J.-H.C., M.-G.P., K.-P.P.) and Radiology (S.K.B.), Pusan National University School of Medicine, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, South Korea; Department of Neurology, Seoul National University Bundang Hospital, South Korea (S.Y.C., J.-S.K.); and Department of Neurology, Pusan National University Hospital, Pusan National University School of Medicine and Biomedical Research Institute, South Korea (K.-D.C.). kdchoi@pusan.ac.kr.
Abstract
BACKGROUND AND PURPOSE: The aim of this study was to determine the prevalence of stroke and efficacy of bedside evaluation in diagnosing stroke in acute transient vestibular syndrome (ATVS). METHODS: We performed a prospective, single-center, observational study that had consecutively recruited 86 patients presenting with ATVS to the emergency department of Pusan National University Yangsan Hospital from January to December 2014. All patients received a constructed evaluation, including HINTS plus (head impulse, nystagmus patterns, test of skew, and finger rubbing) and brain magnetic resonance imagings. Patients without an obvious cause further received perfusion-weighted imaging. Multivariable logistic regression was used to determine clinical parameters to identify stroke in ATVS. RESULTS: The prevalence of stroke was 27% in ATVS. HINTS plus could not be applied to the majority of patients because of the resolution of the vestibular symptoms, and magnetic resonance imagings were falsely negative in 43% of confirmed strokes. Ten patients (12%) showed unilateral cerebellar hypoperfusion on perfusion-weighted imaging without an infarction on diffusion-weighted imaging, and 8 of them had a focal stenosis or hypoplasia of the corresponding vertebral artery. The higher risk of stroke in ATVS was found in association with craniocervical pain (odds ratio, 9.6; 95% confidence interval, 2.0-45.2) and focal neurological symptoms/signs (odds ratio, 15.2; 95% confidence interval, 2.5-93.8). CONCLUSIONS: Bedside examination and routine magnetic resonance imagings have a limitation in diagnosing strokes presenting with ATVS, and perfusion imaging may help to identify strokes in ATVS of unknown cause. Associated craniocervical pain and focal neurological symptoms/signs are the useful clues for strokes in ATVS.
BACKGROUND AND PURPOSE: The aim of this study was to determine the prevalence of stroke and efficacy of bedside evaluation in diagnosing stroke in acute transient vestibular syndrome (ATVS). METHODS: We performed a prospective, single-center, observational study that had consecutively recruited 86 patients presenting with ATVS to the emergency department of Pusan National University Yangsan Hospital from January to December 2014. All patients received a constructed evaluation, including HINTS plus (head impulse, nystagmus patterns, test of skew, and finger rubbing) and brain magnetic resonance imagings. Patients without an obvious cause further received perfusion-weighted imaging. Multivariable logistic regression was used to determine clinical parameters to identify stroke in ATVS. RESULTS: The prevalence of stroke was 27% in ATVS. HINTS plus could not be applied to the majority of patients because of the resolution of the vestibular symptoms, and magnetic resonance imagings were falsely negative in 43% of confirmed strokes. Ten patients (12%) showed unilateral cerebellar hypoperfusion on perfusion-weighted imaging without an infarction on diffusion-weighted imaging, and 8 of them had a focal stenosis or hypoplasia of the corresponding vertebral artery. The higher risk of stroke in ATVS was found in association with craniocervical pain (odds ratio, 9.6; 95% confidence interval, 2.0-45.2) and focal neurological symptoms/signs (odds ratio, 15.2; 95% confidence interval, 2.5-93.8). CONCLUSIONS: Bedside examination and routine magnetic resonance imagings have a limitation in diagnosing strokes presenting with ATVS, and perfusion imaging may help to identify strokes in ATVS of unknown cause. Associated craniocervical pain and focal neurological symptoms/signs are the useful clues for strokes in ATVS.
Authors: Benjamin Nham; Nicole Reid; Kendall Bein; Andrew P Bradshaw; Leigh A McGarvie; Emma C Argaet; Allison S Young; Shaun R Watson; G Michael Halmagyi; Deborah A Black; Miriam S Welgampola Journal: J Neurol Date: 2021-08-16 Impact factor: 4.849
Authors: Ali S Saber Tehrani; Jorge C Kattah; Kevin A Kerber; Daniel R Gold; David S Zee; Victor C Urrutia; David E Newman-Toker Journal: Stroke Date: 2018-02-19 Impact factor: 7.914
Authors: Kailash Krishnan; Kerolos Bassilious; Erik Eriksen; Philip M Bath; Nikola Sprigg; Sigrun Kierulf Brækken; Hege Ihle-Hansen; Morten Andreas Horn; Else Charlotte Sandset Journal: Eur Stroke J Date: 2019-04-10
Authors: Ji-Soo Kim; David E Newman-Toker; Kevin A Kerber; Klaus Jahn; Pierre Bertholon; John Waterston; Hyung Lee; Alexandre Bisdorff; Michael Strupp Journal: J Vestib Res Date: 2022 Impact factor: 2.354
Authors: Yan Fang Peng; Huai Liang Zhang; Dao Pei Zhang; Min Zhao; Shu Ling Zhang; Suo Yin Journal: Ann Clin Transl Neurol Date: 2018-10-12 Impact factor: 4.511