Literature DB >> 28098098

A study of clinical assessment of frailty in patients on maintenance hemodialysis supported by cashless government scheme.

Manjusha Yadla1, Jyothi Priyadarshini John1, Mahesh Mummadi2.   

Abstract

This is a prospective cohort study to assess the prevalence of frailty in patients undergoing maintenance hemodialysis (HD) under the government-funded scheme at our center and to assess the relationship between frailty and falls, hospitalizations, and mortality. This was done at our center which is completely supported by the government, which provides HD to all the patients under poverty line. Epidemiological data, anthropometric measurements, comorbidities assessment, frailty assessment using Fried criteria, subsequent hospitalizations, falls, and mortality were recorded in our prevalent dialysis population at our center between October 2014 and October 2015. Two hundred and twenty-six patients were enrolled during this period. Twenty-one patients were excluded as they did not satisfy the inclusion criteria. Two hundred and five prospective patients were studied for the predictors of frailty. Frailty was present in 82% of the study population. Mean age of our study population was 44.95 ± 13.27 years. On univariate analysis, diabetes mellitus, hypertension (HTN), cerebrovascular accident (CVA), left ventricular dysfunction (LVD), peripheral vascular disease (PVD), smoking, hepatitis C, inadequate dialysis, intradialytic hypotension (IDH), interdialytic weight gain, low serum creatinine <4 mg/dL, and anemia (Hb <10 g/dL) were found to be statistically significantly different between frail and nonfrail groups On multivariate regression analysis, only HTN, PVD, CVA, anemia, smoking, and IDH were found to be significant. Frailty is highly prevalent among dialysis population. Factors predicting frailty include HTN, smoking, LVD, PVD, CVA, smoking, anemia, and IDH. Frailty is a significant risk factor for falls and hospitalizations.

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Year:  2017        PMID: 28098098     DOI: 10.4103/1319-2442.198102

Source DB:  PubMed          Journal:  Saudi J Kidney Dis Transpl        ISSN: 1319-2442


  9 in total

1.  The prevalence of frailty in patients on hemodialysis: a systematic review and meta-analysis.

Authors:  Yaxi Zhao; Qinyu Liu; Jie Ji
Journal:  Int Urol Nephrol       Date:  2019-10-23       Impact factor: 2.370

2.  T Scores, FRAX, Frailty Phenotype, Falls, and Its Relationship to Fractures in Patients on Maintenance Hemodialysis.

Authors:  Maryam Jafari; Salman Anwar; Kaval Kour; Shubrandu Sanjoy; Kunal Goyal; Bhanu Prasad
Journal:  Can J Kidney Health Dis       Date:  2021-08-24

3.  Severity of frailty as a significant predictor of mortality for hemodialysis patients: a prospective study in China.

Authors:  Wenjing Fu; Aihua Zhang; Lina Ma; Linpei Jia; Jagadish K Chhetri; Piu Chan
Journal:  Int J Med Sci       Date:  2021-07-25       Impact factor: 3.738

Review 4.  The impact of frailty on outcomes in dialysis.

Authors:  John Sy; Kirsten L Johansen
Journal:  Curr Opin Nephrol Hypertens       Date:  2017-11       Impact factor: 2.894

5.  Frailty and mortality among patients with chronic kidney disease and end-stage renal disease: a systematic review and meta-analysis.

Authors:  Quanchao Zhang; Yingying Ma; Faying Lin; Jinghong Zhao; Jiachuan Xiong
Journal:  Int Urol Nephrol       Date:  2020-01-18       Impact factor: 2.370

6.  Geriatric Assessment in Elderly Patients with End-Stage Kidney Disease.

Authors:  Namiko A Goto; Ismay N van Loon; Moira I Morpey; Marianne C Verhaar; Hanna C Willems; Mariëlle H Emmelot-Vonk; Michiel L Bots; Franciscus T J Boereboom; Marije E Hamaker
Journal:  Nephron       Date:  2018-11-01       Impact factor: 2.847

7.  The Impact of Frailty on the Outcomes of Hemodialysis Vascular Access.

Authors:  Chiu-Hui Chen; Yu-Ling Hsieh; Shao-Yuan Chuang; Fan-Yin Su; Kuan-Ting Wang; Chien-Ming Luo; Shih-Wei Meng; Chih-Cheng Wu
Journal:  Acta Cardiol Sin       Date:  2022-01       Impact factor: 2.672

Review 8.  Contributors, risk associates, and complications of frailty in patients with chronic kidney disease: a scoping review.

Authors:  Patrick Yihong Wu; Chia-Ter Chao; Ding-Cheng Chan; Jenq-Wen Huang; Kuan-Yu Hung
Journal:  Ther Adv Chronic Dis       Date:  2019-10-05       Impact factor: 5.091

Review 9.  Prevalence and Associated Factors of Frailty and Mortality in Patients with End-Stage Renal Disease Undergoing Hemodialysis: A Systematic Review and Meta-Analysis.

Authors:  Hyeon-Ju Lee; Youn-Jung Son
Journal:  Int J Environ Res Public Health       Date:  2021-03-27       Impact factor: 3.390

  9 in total

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