Literature DB >> 2809584

Effects of melatonin on spontaneous electrical activity of neurons in rat suprachiasmatic nuclei: an in vitro iontophoretic study.

J Stehle1, J Vanecek, L Vollrath.   

Abstract

Circadian rhythms, endogenously generated in suprachiasmatic nuclei (SCN), seem to be under the direct influence of melatonin. Therefore, the effect of iontophoretically applied melatonin on electrical activity of SCN neurons was investigated in vitro. Usually, melatonin had an inhibitory effect. In the 3-h periods before (2.00-5.00 p.m.) or after (5.00-8.00 p.m.) the light-dark transition the percentage of SCN neurons sensitive to melatonin was very high (80% and 100%, respectively). However, efficacy of melatonin was low in the periods preceeding (20%) and following (33%) this 6-h time interval.

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Year:  1989        PMID： 2809584     DOI： 10.1007/bf01252503

Source DB:  PubMed          Journal:  J Neural Transm            Impact factor:   3.575


  14 in total

1.  Day-night differences in the sensitivity of adrenoceptors in the Syrian hamster pineal gland: an in vivo iontophoretic study.

Authors:  J Stehle; S Reuss; L Vollrath
Journal:  Brain Res       Date:  1989-05-29       Impact factor: 3.252

Review 2.  Neural regulation of circadian rhythms.

Authors:  B Rusak; I Zucker
Journal:  Physiol Rev       Date:  1979-07       Impact factor: 37.312

3.  Visual pathways and the central neural control of a circadian rhythm in pineal serotonin N-acetyltransferase activity.

Authors:  R Y Moore; D C Klein
Journal:  Brain Res       Date:  1974-05-10       Impact factor: 3.252

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Authors:  G Groos; J Hendriks
Journal:  Neurosci Lett       Date:  1982-12-31       Impact factor: 3.046

5.  Free-running activity rhythms in the rat: entrainment by melatonin.

Authors:  J Redman; S Armstrong; K T Ng
Journal:  Science       Date:  1983-03-04       Impact factor: 47.728

6.  Circadian rhythm of firing rate recorded from single cells in the rat suprachiasmatic brain slice.

Authors:  D J Green; R Gillette
Journal:  Brain Res       Date:  1982-08-05       Impact factor: 3.252

7.  Circadian rhythmic changes of neuronal activity in the suprachiasmatic nucleus of the rat hypothalamic slice.

Authors:  S Shibata; Y Oomura; H Kita; K Hattori
Journal:  Brain Res       Date:  1982-09-09       Impact factor: 3.252

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Journal:  Neurosci Lett       Date:  1978-09       Impact factor: 3.046

9.  Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions.

Authors:  F K Stephan; I Zucker
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205

Review 10.  Melatonin: a coordinating signal for mammalian reproduction?

Authors:  L Tamarkin; C J Baird; O F Almeida
Journal:  Science       Date:  1985-02-15       Impact factor: 47.728
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  19 in total

1.  Orphanin-FQ/nociceptin (OFQ/N) modulates the activity of suprachiasmatic nucleus neurons.

Authors:  C N Allen; Z G Jiang; K Teshima; T Darland; M Ikeda; C S Nelson; D I Quigley; T Yoshioka; R G Allen; M A Rea; D K Grandy
Journal:  J Neurosci       Date:  1999-03-15       Impact factor: 6.167

2.  Melatonin modulates the neural activity in photosensory pineal organ of the trout: evidence for endocrine-neuronal interactions.

Authors:  H Meissl; C Martin; M Tabata
Journal:  J Comp Physiol A       Date:  1990-11       Impact factor: 1.836

3.  Melatonin binding sites in brain of the 2-day-old chicken: an autoradiographic localisation.

Authors:  J Stehle
Journal:  J Neural Transm Gen Sect       Date:  1990

Review 4.  Understanding melatonin receptor pharmacology: latest insights from mouse models, and their relevance to human disease.

Authors:  Gianluca Tosini; Sharon Owino; Jean-Luc Guillaume; Ralf Jockers
Journal:  Bioessays       Date:  2014-06-05       Impact factor: 4.345

5.  Long-term effects of maternal separation on the responsiveness of the circadian system to melatonin in the diurnal nonhuman primate (Macaca mulatta).

Authors:  Oliver Rawashdeh; Margarita L Dubocovich
Journal:  J Pineal Res       Date:  2014-02-19       Impact factor: 13.007

Review 6.  Functional MT1 and MT2 melatonin receptors in mammals.

Authors:  Margarita L Dubocovich; Magdalena Markowska
Journal:  Endocrine       Date:  2005-07       Impact factor: 3.633

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Authors:  S Reuss
Journal:  Naturwissenschaften       Date:  1993-11

8.  An attempt to correlate brain areas containing melatonin-binding sites with rhythmic functions: a study in five hibernator species.

Authors:  M Masson-Pévet; D George; A Kalsbeek; M Saboureau; N Lakhdar-Ghazal; P Pévet
Journal:  Cell Tissue Res       Date:  1994-10       Impact factor: 5.249

9.  Altered sleep architecture and higher incidence of subsyndromal depression in low endogenous melatonin secretors.

Authors:  Shadab Ataur Rahman; Shai Marcu; Leonid Kayumov; Colin Michael Shapiro
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2009-12-18       Impact factor: 5.270

10.  Time-dependency for the bimodal effect of melatonin on calcium uptake in rat hypothalamus. Short communication.

Authors:  R E Rosenstein; D A Golombek; B I Kanterewicz; D P Cardinali
Journal:  J Neural Transm Gen Sect       Date:  1991
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