Literature DB >> 28089955

Is integrated 18F-FDG PET/MRI superior to 18F-FDG PET/CT in the differentiation of incidental tracer uptake in the head and neck area?

Benedikt Michael Schaarschmidt1, Benedikt Gomez, Christian Buchbender, Johannes Grueneisen, Felix Nensa, Lino Morris Sawicki, Verena Ruhlmann, Axel Wetter, Gerald Antoch, Philipp Heusch.   

Abstract

PURPOSE: We aimed to investigate the accuracy of 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging (18F-FDG PET/MRI) compared with contrast-enhanced 18F-FDG PET/computed tomography (PET/CT) for the characterization of incidental tracer uptake in examinations of the head and neck.
METHODS: A retrospective analysis of 81 oncologic patients who underwent contrast-enhanced 18F-FDG PET/CT and subsequent PET/MRI was performed by two readers for incidental tracer uptake. In a consensus reading, discrepancies were resolved. Each finding was either characterized as most likely benign, most likely malignant, or indeterminate. Using all available clinical information including results from histopathologic sampling and follow-up examinations, an expert reader classified each finding as benign or malignant. McNemar's test was used to compare the performance of both imaging modalities in characterizing incidental tracer uptake.
RESULTS: Forty-six lesions were detected by both modalities. On PET/CT, 27 lesions were classified as most likely benign, one as most likely malignant, and 18 as indeterminate; on PET/MRI, 31 lesions were classified as most likely benign, one lesion as most likely malignant, and 14 as indeterminate. Forty-three lesions were benign and one lesion was malignant according to the reference standard. In two lesions, a definite diagnosis was not possible. McNemar's test detected no differences concerning the correct classification of incidental tracer uptake between PET/CT and PET/MRI (P = 0.125).
CONCLUSION: In examinations of the head and neck area, incidental tracer uptake cannot be classified more accurately by PET/MRI than by PET/CT.

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Year:  2017        PMID: 28089955      PMCID: PMC5338578          DOI: 10.5152/dir.2016.15610

Source DB:  PubMed          Journal:  Diagn Interv Radiol        ISSN: 1305-3825            Impact factor:   2.630


  31 in total

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Authors:  Gerhard W Goerres; Gustav K Von Schulthess; Thomas F Hany
Journal:  AJR Am J Roentgenol       Date:  2002-11       Impact factor: 3.959

2.  Squamous cell carcinoma of the head and neck: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Authors:  V Grégoire; J-L Lefebvre; L Licitra; E Felip
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3.  Can the pathology of a thyroid nodule be determined by positron emission tomography uptake?

Authors:  Jacob Boeckmann; Twyla Bartel; Eric Siegel; Donald Bodenner; Brendan C Stack
Journal:  Otolaryngol Head Neck Surg       Date:  2012-02-03       Impact factor: 3.497

4.  Head and neck incidentalomas on positron emission tomographic scanning: ignore or investigate?

Authors:  Hadi A Al-Hakami; William Makis; Sumeet Anand; Alex Mlynarek; Martin J Black; Jerry Stern; Richard J Payne; Michael P Hier
Journal:  J Otolaryngol Head Neck Surg       Date:  2011-10

5.  Qualitative and quantitative performance of ¹⁸F-FDG-PET/MRI versus ¹⁸F-FDG-PET/CT in patients with head and neck cancer.

Authors:  S Partovi; A Kohan; J L Vercher-Conejero; C Rubbert; S Margevicius; M D Schluchter; C Gaeta; P Faulhaber; M R Robbin
Journal:  AJNR Am J Neuroradiol       Date:  2014-06-12       Impact factor: 3.825

6.  Managing incidental thyroid nodules detected on imaging: white paper of the ACR Incidental Thyroid Findings Committee.

Authors:  Jenny K Hoang; Jill E Langer; William D Middleton; Carol C Wu; Lynwood W Hammers; John J Cronan; Franklin N Tessler; Edward G Grant; Lincoln L Berland
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7.  Accuracy of whole-body dual-modality fluorine-18-2-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography (FDG-PET/CT) for tumor staging in solid tumors: comparison with CT and PET.

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8.  CT and MR imaging of squamous cell carcinoma of the tongue and floor of the mouth.

Authors:  R Sigal; A M Zagdanski; G Schwaab; J Bosq; A Auperin; A Laplanche; J P Francke; F Eschwège; B Luboinski; D Vanel
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9.  Frequency and clinical implications of incidental new primary cancers detected on true whole-body 18F-FDG PET/CT studies.

Authors:  Ronnie Sebro; Carina Mari Aparici; Miguel Hernandez Pampaloni
Journal:  Nucl Med Commun       Date:  2013-04       Impact factor: 1.690

10.  Whole-body dual-modality PET/CT and whole-body MRI for tumor staging in oncology.

Authors:  Gerald Antoch; Florian M Vogt; Lutz S Freudenberg; Fridun Nazaradeh; Susanne C Goehde; Jörg Barkhausen; Gerlinde Dahmen; Andreas Bockisch; Jörg F Debatin; Stefan G Ruehm
Journal:  JAMA       Date:  2003-12-24       Impact factor: 56.272

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  2 in total

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Authors:  Haodan Dang; Yu Chen; Zhuhua Zhang; Xiaohua Shi; Xingming Chen; Xiaoli Zhu; Bo Hou; Haiqun Xing; Huadan Xue; Zhengyu Jin
Journal:  Dentomaxillofac Radiol       Date:  2020-04-03       Impact factor: 2.419

2.  Are Gadolinium-Enhanced MR Sequences Needed in Simultaneous 18F-FDG-PET/MRI for Tumor Delineation in Head and Neck Cancer?

Authors:  N Pyatigorskaya; R De Laroche; G Bera; A Giron; C Bertolus; G Herve; E Chambenois; S Bergeret; D Dormont; M Amor-Sahli; A Kas
Journal:  AJNR Am J Neuroradiol       Date:  2020-09-24       Impact factor: 4.966

  2 in total

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