Literature DB >> 28085162

High-resolution sub-cellular imaging by correlative NanoSIMS and electron microscopy of amiodarone internalisation by lung macrophages as evidence for drug-induced phospholipidosis.

Haibo Jiang1, Melissa K Passarelli2, Peter M G Munro3, Matt R Kilburn1, Andrew West4, Colin T Dollery4, Ian S Gilmore2, Paulina D Rakowska2.   

Abstract

Correlative NanoSIMS and EM imaging of amiodarone-treated macrophages shows the internalisation of the drug at a sub-cellular level and reveals its accumulation within the lysosomes, providing direct evidence for amiodarone-induced phospholipidosis. Chemical fixation using tannic acid effectively seals cellular membranes aiding intracellular retention of diffusible drugs.

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Year:  2017        PMID： 28085162     DOI： 10.1039/c6cc08549k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  10 in total

Review 1.  Exploring the Fundamental Structures of Life: Non-Targeted, Chemical Analysis of Single Cells and Subcellular Structures.

Authors:  Elizabeth K Neumann; Thanh D Do; Troy J Comi; Jonathan V Sweedler
Journal:  Angew Chem Int Ed Engl       Date:  2019-04-11       Impact factor: 15.336

2.  Inkjet-printed micro-calibration standards for ultraquantitative Raman spectral cytometry.

Authors:  Vernon LaLone; Maria V Fawaz; Jomar Morales-Mercado; Márcio A Mourão; Catherine S Snyder; Sang Yeop Kim; Andrew P Lieberman; Anish Tuteja; Geeta Mehta; Theodore J Standiford; Krishnan Raghavendran; Kerby Shedden; Anna Schwendeman; Kathleen A Stringer; Gus R Rosania
Journal:  Analyst       Date:  2019-05-22       Impact factor: 4.616

3.  The 3D OrbiSIMS-label-free metabolic imaging with subcellular lateral resolution and high mass-resolving power.

Authors:  Melissa K Passarelli; Alexander Pirkl; Rudolf Moellers; Dmitry Grinfeld; Felix Kollmer; Rasmus Havelund; Carla F Newman; Peter S Marshall; Henrik Arlinghaus; Morgan R Alexander; Andy West; Stevan Horning; Ewald Niehuis; Alexander Makarov; Colin T Dollery; Ian S Gilmore
Journal:  Nat Methods       Date:  2017-11-13       Impact factor: 28.547

Review 4.  Alveolar lipids in pulmonary disease. A review.

Authors:  Christina W Agudelo; Ghassan Samaha; Itsaso Garcia-Arcos
Journal:  Lipids Health Dis       Date:  2020-06-03       Impact factor: 3.876

5.  Optimizing colormaps with consideration for color vision deficiency to enable accurate interpretation of scientific data.

Authors:  Jamie R Nuñez; Christopher R Anderton; Ryan S Renslow
Journal:  PLoS One       Date:  2018-08-01       Impact factor: 3.240

6.  Subcellular Mass Spectrometry Imaging and Absolute Quantitative Analysis across Organelles.

Authors:  Aurélien Thomen; Neda Najafinobar; Florent Penen; Emma Kay; Pratik P Upadhyay; Xianchan Li; Nhu T N Phan; Per Malmberg; Magnus Klarqvist; Shalini Andersson; Michael E Kurczy; Andrew G Ewing
Journal:  ACS Nano       Date:  2020-04-08       Impact factor: 15.881

7.  Correlative light electron ion microscopy reveals in vivo localisation of bedaquiline in Mycobacterium tuberculosis-infected lungs.

Authors:  Antony Fearns; Daniel J Greenwood; Angela Rodgers; Haibo Jiang; Maximiliano G Gutierrez
Journal:  PLoS Biol       Date:  2020-12-31       Impact factor: 8.029

8.  High-resolution visualization and quantification of nucleic acid-based therapeutics in cells and tissues using Nanoscale secondary ion mass spectrometry (NanoSIMS).

Authors:  Cuiwen He; Michael T Migawa; Kai Chen; Thomas A Weston; Michael Tanowitz; Wenxin Song; Paul Guagliardo; K Swaminathan Iyer; C Frank Bennett; Loren G Fong; Punit P Seth; Stephen G Young; Haibo Jiang
Journal:  Nucleic Acids Res       Date:  2021-01-11       Impact factor: 16.971

Review 9.  Advances in MALDI Mass Spectrometry Imaging Single Cell and Tissues.

Authors:  Xiaoping Zhu; Tianyi Xu; Chen Peng; Shihua Wu
Journal:  Front Chem       Date:  2022-02-03       Impact factor: 5.221

10.  Visualization of Partial Exocytotic Content Release and Chemical Transport into Nanovesicles in Cells.

Authors:  Tho Duc Khanh Nguyen; Lisa Mellander; Alicia Lork; Aurélien Thomen; Mai Philipsen; Michael E Kurczy; Nhu T N Phan; Andrew G Ewing
Journal:  ACS Nano       Date:  2022-02-21       Impact factor: 15.881
  10 in total

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