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Literature DB >> 28084830

Simplification of a Septic Shock Endotyping Strategy for Clinical Application.

Hector R Wong^1,2,3, Timothy E Sweeney⁴, Christopher J Lindsell³.

Abstract

Entities: Disease

Mesh：

Year: 2017 PMID： 28084830 PMCID： PMC5394789 DOI： 10.1164/rccm.201607-1535LE

Source DB: PubMed Journal: Am J Respir Crit Care Med ISSN： 1073-449X Impact factor: 21.405

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10 in total

1. Combining Prognostic and Predictive Enrichment Strategies to Identify Children With Septic Shock Responsive to Corticosteroids.

Authors: Hector R Wong; Sarah J Atkinson; Natalie Z Cvijanovich; Nick Anas; Geoffrey L Allen; Neal J Thomas; Michael T Bigham; Scott L Weiss; Julie C Fitzgerald; Paul A Checchia; Keith Meyer; Michael Quasney; Mark Hall; Rainer Gedeit; Robert J Freishtat; Jeffrey Nowak; Shekhar S Raj; Shira Gertz; Christopher J Lindsell
Journal: Crit Care Med Date: 2016-10 Impact factor: 7.598

2. Validation of a gene expression-based subclassification strategy for pediatric septic shock.

Authors: Hector R Wong; Natalie Z Cvijanovich; Geoffrey L Allen; Neal J Thomas; Robert J Freishtat; Nick Anas; Keith Meyer; Paul A Checchia; Richard Lin; Thomas P Shanley; Michael T Bigham; Derek S Wheeler; Lesley A Doughty; Ken Tegtmeyer; Sue E Poynter; Jennifer M Kaplan; Ranjit S Chima; Erika Stalets; Rajit K Basu; Brian M Varisco; Frederick E Barr
Journal: Crit Care Med Date: 2011-11 Impact factor: 7.598

3. Toward a clinically feasible gene expression-based subclassification strategy for septic shock: proof of concept.

Authors: Hector R Wong; Derek S Wheeler; Ken Tegtmeyer; Sue E Poynter; Jennifer M Kaplan; Ranjit S Chima; Erika Stalets; Rajit K Basu; Lesley A Doughty
Journal: Crit Care Med Date: 2010-10 Impact factor: 7.598

4. Developing a clinically feasible personalized medicine approach to pediatric septic shock.

Authors: Hector R Wong; Natalie Z Cvijanovich; Nick Anas; Geoffrey L Allen; Neal J Thomas; Michael T Bigham; Scott L Weiss; Julie Fitzgerald; Paul A Checchia; Keith Meyer; Thomas P Shanley; Michael Quasney; Mark Hall; Rainer Gedeit; Robert J Freishtat; Jeffrey Nowak; Raj S Shekhar; Shira Gertz; Emily Dawson; Kelli Howard; Kelli Harmon; Eileen Beckman; Erin Frank; Christopher J Lindsell
Journal: Am J Respir Crit Care Med Date: 2015-02-01 Impact factor: 21.405

Review 5. Gene expression profiling in sepsis: timing, tissue, and translational considerations.

Authors: David M Maslove; Hector R Wong
Journal: Trends Mol Med Date: 2014-02-15 Impact factor: 11.951

6. Identifying critically ill patients who may benefit from adjunctive corticosteroids: not as easy as we thought.

Authors: Sarah J Atkinson; Hector R Wong
Journal: Pediatr Crit Care Med Date: 2014-10 Impact factor: 3.624

7. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock.

Authors: Djillali Annane; Véronique Sébille; Claire Charpentier; Pierre-Edouard Bollaert; Bruno François; Jean-Michel Korach; Gilles Capellier; Yves Cohen; Elie Azoulay; Gilles Troché; Philippe Chaumet-Riffaud; Philippe Chaumet-Riffaut; Eric Bellissant
Journal: JAMA Date: 2002-08-21 Impact factor: 56.272

8. Hydrocortisone therapy for patients with septic shock.

Authors: Charles L Sprung; Djillali Annane; Didier Keh; Rui Moreno; Mervyn Singer; Klaus Freivogel; Yoram G Weiss; Julie Benbenishty; Armin Kalenka; Helmuth Forst; Pierre-Francois Laterre; Konrad Reinhart; Brian H Cuthbertson; Didier Payen; Josef Briegel
Journal: N Engl J Med Date: 2008-01-10 Impact factor: 91.245

9. Corticosteroids and pediatric septic shock outcomes: a risk stratified analysis.

Authors: Sarah J Atkinson; Natalie Z Cvijanovich; Neal J Thomas; Geoffrey L Allen; Nick Anas; Michael T Bigham; Mark Hall; Robert J Freishtat; Anita Sen; Keith Meyer; Paul A Checchia; Thomas P Shanley; Jeffrey Nowak; Michael Quasney; Scott L Weiss; Sharon Banschbach; Eileen Beckman; Kelli Howard; Erin Frank; Kelli Harmon; Patrick Lahni; Christopher J Lindsell; Hector R Wong
Journal: PLoS One Date: 2014-11-11 Impact factor: 3.240

10. Identification of pediatric septic shock subclasses based on genome-wide expression profiling.

Authors: Hector R Wong; Natalie Cvijanovich; Richard Lin; Geoffrey L Allen; Neal J Thomas; Douglas F Willson; Robert J Freishtat; Nick Anas; Keith Meyer; Paul A Checchia; Marie Monaco; Kelli Odom; Thomas P Shanley
Journal: BMC Med Date: 2009-07-22 Impact factor: 8.775

10 in total

8 in total

1. Disseminated Intravascular Coagulation Is an Independent Predictor of Adverse Outcomes in Children in the Emergency Department with Suspected Sepsis.

Authors: Leonora R Slatnick; Dianne Thornhill; Sara J Deakyne Davies; James B Ford; Halden F Scott; Marilyn J Manco-Johnson; Beth Boulden Warren
Journal: J Pediatr Date: 2020-06-14 Impact factor: 4.406

Review 2. Sepsis Biomarkers.

Authors: Hector R Wong
Journal: J Pediatr Intensive Care Date: 2019-01-11

Simplification of a Septic Shock Endotyping Strategy for Clinical Application.

1. Combining Prognostic and Predictive Enrichment Strategies to Identify Children With Septic Shock Responsive to Corticosteroids.

2. Validation of a gene expression-based subclassification strategy for pediatric septic shock.

3. Toward a clinically feasible gene expression-based subclassification strategy for septic shock: proof of concept.

4. Developing a clinically feasible personalized medicine approach to pediatric septic shock.

Review 5. Gene expression profiling in sepsis: timing, tissue, and translational considerations.

6. Identifying critically ill patients who may benefit from adjunctive corticosteroids: not as easy as we thought.

7. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock.

8. Hydrocortisone therapy for patients with septic shock.

9. Corticosteroids and pediatric septic shock outcomes: a risk stratified analysis.

10. Identification of pediatric septic shock subclasses based on genome-wide expression profiling.

1. Disseminated Intravascular Coagulation Is an Independent Predictor of Adverse Outcomes in Children in the Emergency Department with Suspected Sepsis.

Review 2. Sepsis Biomarkers.

3. Markers of Endothelial Dysfunction and Cytokines in High-Risk Pediatric Patients with Severe Sepsis.

Review 4. Precision medicine in pediatric sepsis.

5. Pediatric Sepsis Endotypes Among Adults With Sepsis.

6. Intensive care medicine in 2050: precision medicine.

Review 7. Prognostic and predictive enrichment in sepsis.

Review 8. Sepsis therapies: learning from 30 years of failure of translational research to propose new leads.