Literature DB >> 28082737

Phosphoproteomic analysis reveals hyperactivation of mTOR/STAT3 and LCK/Calcineurin axes in pediatric early T-cell precursor ALL.

V Serafin1, V Lissandron1, B Buldini1, S Bresolin1, M Paganin1, F Grillo1, N Andriano2, C Palmi2, G Cazzaniga2, S Marmiroli3, V Conter4, G Basso1, B Accordi1.   

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Year:  2017        PMID： 28082737     DOI： 10.1038/leu.2017.13

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  21 in total

1.  A global test for groups of genes: testing association with a clinical outcome.

Authors:  Jelle J Goeman; Sara A van de Geer; Floor de Kort; Hans C van Houwelingen
Journal:  Bioinformatics       Date:  2004-01-01       Impact factor: 6.937

2.  Synergistic activity of rapamycin and dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis.

Authors:  Chong Zhang; Yong-Ku Ryu; Taylor Z Chen; Connor P Hall; Daniel R Webster; Min H Kang
Journal:  Leuk Res       Date:  2011-12-03       Impact factor: 3.156

3.  A Phase I/II Study of the mTOR Inhibitor Everolimus in Combination with HyperCVAD Chemotherapy in Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia.

Authors:  Naval Daver; Yanis Boumber; Hagop Kantarjian; Farhad Ravandi; Jorge Cortes; Michael E Rytting; Jitesh D Kawedia; Jordan Basnett; Kirk S Culotta; Zhihong Zeng; Hongbo Lu; Mary Ann Richie; Rebecca Garris; Lianchun Xiao; Wenbin Liu; Keith A Baggerly; Elias Jabbour; Susan O'Brien; Jan Burger; Linda J Bendall; Deborah Thomas; Marina Konopleva
Journal:  Clin Cancer Res       Date:  2015-02-27       Impact factor: 12.531

4.  Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia.

Authors:  Shannon L Maude; Sibasish Dolai; Cristina Delgado-Martin; Tiffaney Vincent; Alissa Robbins; Arthavan Selvanathan; Theresa Ryan; Junior Hall; Andrew C Wood; Sarah K Tasian; Stephen P Hunger; Mignon L Loh; Charles G Mullighan; Brent L Wood; Michelle L Hermiston; Stephan A Grupp; Richard B Lock; David T Teachey
Journal:  Blood       Date:  2015-02-02       Impact factor: 22.113

5.  NUP214-ABL1-mediated cell proliferation in T-cell acute lymphoblastic leukemia is dependent on the LCK kinase and various interacting proteins.

Authors:  Kim De Keersmaecker; Michaël Porcu; Luk Cox; Tiziana Girardi; Roel Vandepoel; Joyce Op de Beeck; Olga Gielen; Nicole Mentens; Keiryn L Bennett; Oliver Hantschel
Journal:  Haematologica       Date:  2013-07-19       Impact factor: 9.941

Review 6.  mTORC1 signaling and IL-17 expression: Defining pathways and possible therapeutic targets.

Authors:  Wenkai Ren; Jie Yin; Jielin Duan; Gang Liu; Bie Tan; Guan Yang; Guoyao Wu; Fuller W Bazer; Yuanyi Peng; Yulong Yin
Journal:  Eur J Immunol       Date:  2015-12-22       Impact factor: 5.532

7.  PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors.

Authors:  Annalisa Lonetti; Alessandra Cappellini; Antonino Maria Spartà; Francesca Chiarini; Francesca Buontempo; Camilla Evangelisti; Cecilia Evangelisti; Ester Orsini; James A McCubrey; Alberto Maria Martelli
Journal:  Oncotarget       Date:  2015-04-30

8.  Low PKCα expression within the MRD-HR stratum defines a new subgroup of childhood T-ALL with very poor outcome.

Authors:  Gloria Milani; Paola Rebora; Benedetta Accordi; Luisa Galla; Silvia Bresolin; Gianni Cazzaniga; Barbara Buldini; Rossella Mura; Saverio Ladogana; Eugenia Giraldi; Valentino Conter; Geertruy Te Kronnie; Maria Grazia Valsecchi; Giuseppe Basso
Journal:  Oncotarget       Date:  2014-07-30

9.  Outcome for children and young people with Early T-cell precursor acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003.

Authors:  Katharine Patrick; Rachel Wade; Nick Goulden; Chris Mitchell; Anthony V Moorman; Clare Rowntree; Sarah Jenkinson; Rachael Hough; Ajay Vora
Journal:  Br J Haematol       Date:  2014-04-08       Impact factor: 6.998

10.  CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation.

Authors:  Yao-An Shen; Chia-Yu Wang; Hui-Yen Chuang; John Jeng-Jong Hwang; Wei-Hsin Chi; Chih-Hung Shu; Ching-Yin Ho; Wing-Yin Li; Yann-Jang Chen
Journal:  Oncotarget       Date:  2016-09-06
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  8 in total

1.  Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia.

Authors:  Yalu Zhou; Cuijuan Han; Eric Wang; Adam H Lorch; Valentina Serafin; Byoung-Kyu Cho; Blanca T Gutierrez Diaz; Julien Calvo; Celestia Fang; Alireza Khodadadi-Jamayran; Tommaso Tabaglio; Christian Marier; Anna Kuchmiy; Limin Sun; George Yacu; Szymon K Filip; Qi Jin; Yoh-Hei Takahashi; David R Amici; Emily J Rendleman; Radhika Rawat; Silvia Bresolin; Maddalena Paganin; Cheng Zhang; Hu Li; Irawati Kandela; Yuliya Politanska; Hiam Abdala-Valencia; Marc L Mendillo; Ping Zhu; Bruno Palhais; Pieter Van Vlierberghe; Tom Taghon; Iannis Aifantis; Young Ah Goo; Ernesto Guccione; Adriana Heguy; Aristotelis Tsirigos; Keng Boon Wee; Rama K Mishra; Francoise Pflumio; Benedetta Accordi; Giuseppe Basso; Panagiotis Ntziachristos
Journal:  Cancer Discov       Date:  2020-05-22       Impact factor: 39.397

2.  Identification of key candidate genes and miRNA‑mRNA target pairs in chronic lymphocytic leukemia by integrated bioinformatics analysis.

Authors:  Chundi Gao; Chao Zhou; Jing Zhuang; Lijuan Liu; Junyu Wei; Cun Liu; Huayao Li; Changgang Sun
Journal:  Mol Med Rep       Date:  2018-11-09       Impact factor: 2.952

3.  JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction.

Authors:  Luca Simula; Mauro Corrado; Benedetta Accordi; Anthea Di Rita; Francesca Nazio; Ylenia Antonucci; Arianna Di Daniele; Federico Caicci; Ignazio Caruana; Maria Eugenia Soriano; Martina Pigazzi; Franco Locatelli; Francesco Cecconi; Silvia Campello
Journal:  Cell Death Differ       Date:  2020-04-28       Impact factor: 15.828

4.  HSP90 inhibitor NVP-BEP800 affects stability of SRC kinases and growth of T-cell and B-cell acute lymphoblastic leukemias.

Authors:  Rony Mshaik; John Simonet; Aleksandra Georgievski; Layla Jamal; Shaliha Bechoua; Paola Ballerini; Pierre-Simon Bellaye; Zandile Mlamla; Jean-Paul Pais de Barros; Audrey Geissler; Pierre-Jean Francin; François Girodon; Carmen Garrido; Ronan Quéré
Journal:  Blood Cancer J       Date:  2021-03-18       Impact factor: 11.037

Review 5.  T-Cell Acute Lymphoblastic Leukemia: Biomarkers and Their Clinical Usefulness.

Authors:  Valentina Bardelli; Silvia Arniani; Valentina Pierini; Danika Di Giacomo; Tiziana Pierini; Paolo Gorello; Cristina Mecucci; Roberta La Starza
Journal:  Genes (Basel)       Date:  2021-07-23       Impact factor: 4.096

6.  Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies.

Authors:  Valentina Cordo'; Mariska T Meijer; Rico Hagelaar; Richard R de Goeij-de Haas; Vera M Poort; Alex A Henneman; Sander R Piersma; Thang V Pham; Koichi Oshima; Adolfo A Ferrando; Guido J R Zaman; Connie R Jimenez; Jules P P Meijerink
Journal:  Nat Commun       Date:  2022-02-25       Impact factor: 17.694

7.  Phospho-Specific Flow Cytometry Reveals Signaling Heterogeneity in T-Cell Acute Lymphoblastic Leukemia Cell Lines.

Authors:  Omar Perbellini; Chiara Cavallini; Roberto Chignola; Marilisa Galasso; Maria T Scupoli
Journal:  Cells       Date:  2022-06-29       Impact factor: 7.666

8.  USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia.

Authors:  Qi Jin; Carlos A Martinez; Kelly M Arcipowski; Yixing Zhu; Blanca T Gutierrez-Diaz; Kenneth K Wang; Megan R Johnson; Andrew G Volk; Feng Wang; Jian Wu; Charles Grove; Hui Wang; Ivan Sokirniy; Paul M Thomas; Young Ah Goo; Nebiyu A Abshiru; Nobuko Hijiya; Sofie Peirs; Niels Vandamme; Geert Berx; Steven Goosens; Stacy A Marshall; Emily J Rendleman; Yoh-Hei Takahashi; Lu Wang; Radhika Rawat; Elizabeth T Bartom; Clayton K Collings; Pieter Van Vlierberghe; Alexandros Strikoudis; Stephen Kelly; Beatrix Ueberheide; Christine Mantis; Irawati Kandela; Jean-Pierre Bourquin; Beat Bornhauser; Valentina Serafin; Silvia Bresolin; Maddalena Paganin; Benedetta Accordi; Giuseppe Basso; Neil L Kelleher; Joseph Weinstock; Suresh Kumar; John D Crispino; Ali Shilatifard; Panagiotis Ntziachristos
Journal:  Clin Cancer Res       Date:  2018-09-17       Impact factor: 12.531
  8 in total

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