Literature DB >> 28079225

Bioconjugation strategies to couple supramolecular exo-functionalized palladium cages to peptides for biomedical applications.

J Han1, A Schmidt2, T Zhang3, H Permentier3, G M M Groothuis4, R Bischoff3, F E Kühn2, P Horvatovich3, A Casini5.   

Abstract

Supramolecular Pd2L4 cages (L = ligand) hold promise as drug delivery systems. With the idea of achieving targeted delivery of the metallacages to tumor cells, the bioconjugation of exo-functionalized self-assembled Pd2L4 cages to peptides following two different approaches is reported for the first time. The obtained bioconjugates were analyzed and identified by high-resolution mass spectrometry.

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Year:  2017        PMID： 28079225     DOI： 10.1039/c6cc08937b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Biomedical Applications of Metal Organic Polygons and Polyhedra (MOPs).

Authors:  Soumen K Samanta; Lyle Isaacs
Journal:  Coord Chem Rev       Date:  2020-02-19       Impact factor: 22.315

Review 2.  Biomedically Relevant Self-Assembled Metallacycles and Metallacages.

Authors:  Hajar Sepehrpour; Wenxin Fu; Yan Sun; Peter J Stang
Journal:  J Am Chem Soc       Date:  2019-08-29       Impact factor: 15.419

3.  Anticancer Activity and Cisplatin Binding Ability of Bis-Quinoline and Bis-Isoquinoline Derived [Pd2L4]4+ Metallosupramolecular Cages.

Authors:  Roan A S Vasdev; Lachlan F Gaudin; Dan Preston; Jackmil P Jogy; Gregory I Giles; James D Crowley
Journal:  Front Chem       Date:  2018-11-22       Impact factor: 5.221

Review 4.  Recent Developments of Supramolecular Metal-based Structures for Applications in Cancer Therapy and Imaging.

Authors:  Alexander Pöthig; Angela Casini
Journal:  Theranostics       Date:  2019-05-18       Impact factor: 11.556
  4 in total

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