BACKGROUND: Female gender is accepted as a poor prognostic factor for Fournier's gangrene (FG). However, there is a paucity of data in the literature regarding this matter. This case-matched study was designed to investigate the impact of gender on outcomes of FG. METHODS: Study patient data were retrieved from 120-patient, prospectively maintained database. Thirty-two female patients with FG were case-matched to 32 male patients based on symptom duration (days), FG severity index score, patient age, etiology, and presence of diabetes mellitus (DM) terms. Outcomes of FG were compared between the 2 groups. RESULTS: Median age was 57 years (range: 22-80 years), and 35 (54.7%) patients had DM. Patients underwent average of 3 debridement procedures (range: 1-9 debridements), and 15 (23.4%) received diverting stoma. Overall mortality rate was 28.1% (18 of 64 patients). Female gender was associated with widespread disease (p=0.009), increased need for consecutive debridements (p=0.005), prolonged length of intensive care unit stay (p=0.035), and increased requirement for split-thickness skin graft reconstruction (p=0.040). However, mortality rates were comparable between genders (p=0.264). CONCLUSION: FG is often more extensive in females and seems to be associated with anatomical features of female pelvis. However, female gender is not a factor affecting prognosis of patients with FG.
BACKGROUND: Female gender is accepted as a poor prognostic factor for Fournier's gangrene (FG). However, there is a paucity of data in the literature regarding this matter. This case-matched study was designed to investigate the impact of gender on outcomes of FG. METHODS: Study patient data were retrieved from 120-patient, prospectively maintained database. Thirty-two female patients with FG were case-matched to 32 male patients based on symptom duration (days), FG severity index score, patient age, etiology, and presence of diabetes mellitus (DM) terms. Outcomes of FG were compared between the 2 groups. RESULTS: Median age was 57 years (range: 22-80 years), and 35 (54.7%) patients had DM. Patients underwent average of 3 debridement procedures (range: 1-9 debridements), and 15 (23.4%) received diverting stoma. Overall mortality rate was 28.1% (18 of 64 patients). Female gender was associated with widespread disease (p=0.009), increased need for consecutive debridements (p=0.005), prolonged length of intensive care unit stay (p=0.035), and increased requirement for split-thickness skin graft reconstruction (p=0.040). However, mortality rates were comparable between genders (p=0.264). CONCLUSION: FG is often more extensive in females and seems to be associated with anatomical features of female pelvis. However, female gender is not a factor affecting prognosis of patients with FG.
Authors: Laila Schneidewind; Petra Anheuser; Sandra Schönburg; Florian M E Wagenlehner; Jennifer Kranz Journal: Urol Int Date: 2020-12-07 Impact factor: 2.089
Authors: Jennifer Kranz; Florian M E Wagenlehner; Joachim Steffens; Oliver W Hakenberg; Laila Schneidewind Journal: Urologe A Date: 2021-02-09 Impact factor: 0.639
Authors: Orestis Ioannidis; Loukiani Kitsikosta; Dimitris Tatsis; Ioannis Skandalos; Aggeliki Cheva; Aikaterini Gkioti; Ioannis Varnalidis; Savvas Symeonidis; Natalia Antigoni Savvala; Styliani Parpoudi; George K Paraskevas; Manousos George Pramateftakis; Efstathios Kotidis; Ioannis Mantzoros; Konstantinos George Tsalis Journal: Front Surg Date: 2017-07-10
Authors: Jennifer Kranz; Daniel Schlager; Petra Anheuser; Sandra Mühlstädt; Benedict Brücher; Tanja Frank; Dimitri Barski; Roman Mayr; Andreas Lunacek; Eric Francis Macharia-Nimietz; Joachim A Steffens; Johannes Grolle; Alexandre Pelzer; Laila Schneidewind Journal: Cent European J Urol Date: 2018-09-22