| Literature DB >> 28068402 |
Ziyan Chen1, Xianchai Lin1, Bo Qu1, Wuyou Gao1, Yajing Zuo1, Wenyan Peng1, Ling Jin1, Minbin Yu1, Ecosse Lamoureux2,3,4.
Abstract
PURPOSE: To investigate the relationship between preoperative expectations and actual postoperative outcomes of visual function (VF) among patients undergoing first eye cataract surgery.Entities:
Mesh:
Year: 2017 PMID: 28068402 PMCID: PMC5222503 DOI: 10.1371/journal.pone.0169844
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Baseline demographic, health, ocular and visual functional characteristics of the participants had cataract surgery in only one eye (N = 182).
| Characteristics | N | n (%) |
|---|---|---|
| 175 | ||
| ≤60 | 25 (14.3) | |
| 60–70 | 51 (29.1) | |
| 70–80 | 65 (37.1) | |
| >80 | 34 (19.4) | |
| Mean (SD), range | 71.0 (11.6), (21–90) | |
| 182 | ||
| Male | 94 (51.7) | |
| Female | 88 (48.3) | |
| 173 | ||
| Primary school or lower | 90 (52.0) | |
| Junior school or higher | 83 (48.0) | |
| 182 | ||
| Inadequate | 72 (39.6) | |
| Adequate | 110 (60.4) | |
| 182 | ||
| Inadequate | 179 (98.4) | |
| Adequate | 3 (1.60) | |
| Hypertension | 182 | 27 (14.8) |
| Diabetes | 182 | 35 (19.2) |
| Others | 182 | 30 (16.5) |
| Any of the above | 182 | 83 (45.6) |
| No | 182 | 99 (54.4) |
| Glaucoma | 182 | 5 (2.75) |
| AMD | 182 | 3 (1.65) |
| Diabetic retinopathy | 182 | 14 (7.69) |
| Others | 182 | 34 (18.7) |
| Any of the above | 182 | 54 (29.7) |
| No | 182 | 128 (70.3) |
| 174 | ||
| >6/60 | 45 (25.9) | |
| >6/120 - ≤6/60 | 39 (22.4) | |
| ≤6/120 | 90 (51.7) | |
| | 179 | |
| ≤3 | 76 (42.5) | |
| >3 - ≤5 | 80 (44.7) | |
| >5 | 23 (12.8) | |
| | 181 | |
| ≤3 | 89 (49.2) | |
| >3 - ≤4 | 57 (31.5) | |
| >4 | 35 (19.3) | |
| 161 | ||
| Aspherical IOL | 96 (59.6) | |
| Spherical IOL | 65 (40.4) | |
| 179 | ||
| Very difficult | 51 (28.5) | |
| Moderately difficult | 57 (31.8) | |
| Little difficult | 62 (34.6) | |
| Not difficult | 9 (5.03) | |
| 182 | ||
| Very dissatisfied | 89 (48.9) | |
| Dissatisfied | 72 (39.6) | |
| Satisfied | 17 (9.34) | |
| Very satisfied | 4 (2.20) | |
| Mean (SD), range | 182 | 15.7 (5.86), (7–28) |
| Mean (SD), range | 182 | 26.3 (2.93), (12–28) |
SD = Standard Deviation AMD = Age-related macular degeneration LOCS = Lens opacities classification system.
NO = Nuclear opalescence C = Cortical cataract IOL = Intraocular lens.
* The preoperative Catquest-9SF score was the total score of each preoperative item-specific score with range from 7 to 28.
** The expected postoperative Catquest-9SF score was calculated by adjusting each preoperative item-specific score upward by the amount of expected postoperative improvement coded as 1 = a little improvement, 2 = moderate improvement and 3 = great improvement. The maximum expected postoperative score for each item was limited to 4 and the range of the total expected postoperative score was 7–28.
Preoperative difficulty, expected and actual postoperative improvement on the Catquest-9SF items by demographics (N = 174)§.
| Catquest-9SF score Median (IQR) | Subjects achieving expected improvement n (%) | |||||
|---|---|---|---|---|---|---|
| Characteristics | Number of subjects | Preoperative | Expected postoperative | Actual postoperative | Difference of postoperative (Actual—Expected) | |
| ≤60 | 25 | 17 (14–21) | 28 (24–28) | 28 (24–28) | 0 (-2–1) | 15 (60.0) |
| 61–70 | 49 | 16 (11–20) | 28 (25–28) | 26 (24–28) | -1 (-3–0) | 23 (46.9) |
| 71–80 | 62 | 14.5 (10–19) | 28 (27–28) | 27 (24–28) | 0 (-3–0) | 35 (56.5) |
| >80 | 31 | 14 (10–18) | 28 (24–28) | 27 (25–28) | 0 (-2–2) | 18 (58.1) |
| Male | 89 | 17 (13–21) | 28 (27–28) | 28 (25–28) | 0 (-2–0) | 44 (49.4) |
| Female | 85 | 14 (10–20) | 28 (24–28) | 26 (23–28) | -1 (-3–0) | 51 (60.0) |
| Primary school or lower | 86 | 16 (12–21) | 28 (25–28) | 27 (24–28) | 0 (-3–0) | 46 (53.5) |
| Junior school or higher | 79 | 16 (11–20) | 28 (25–28) | 27 (25–28) | 0 (-2–0) | 45 (57.0) |
| Inadequate | 68 | 14 (9–18) | 28 (24–28) | 25 (21.5–28)** | -1 (-3–1) | 30 (44.1) |
| Adequate | 106 | 18 (13–21) | 28 (26–28) | 28 (25–28) | 0 (-2–0) | 65 (61.3) * |
| Inadequate | 171 | 15 (11–21) | 28 (25–28) | 27 (24–28)** | 0 (-3–0) | 94 (55.0) |
| Adequate | 3 | 18 (16–25) | 28 (28–28) | 27 (26–28) | -1 (-2–0) | 1 (33.3) |
| Yes | 26 | 12.5 (7–20) | 26 (21–28) | 24 (21–26) | -2 (-3–0) | 11 (42.3) |
| No | 148 | 16 (12.5–21) | 28 (25.5–28) | 27 (25–28)* | 0 (-2–0) | 84 (56.8) |
| Yes | 34 | 14.5 (10–19) | 28 (25–28) | 25 (21–27) | -1.5 (-4–0)* | 13 (39.4) |
| No | 140 | 16 (11.5–21) | 28 (25–28) | 27 (25–28)*** | 0 (-2–1) | 81 (57.9) |
| Yes | 80 | 14 (8.5–19.5) | 26 (24.5–28) | 26 (24–28)** | 0 (-3–0) | 41 (51.3) |
| No | 94 | 18 (14–21) | 28 (26–28) | 28 (25–28) | 0 (-3–1) | 54 (57.5) |
IQR = Inter Quartile Range AMD = Age-related macular degeneration.
§ Among 182 who had surgery, 174 (95.6%) persons had complete pre and post operative Catquest-9 SF data.
†The Wilcoxon signed rank sum test was used for comparing the difference between actual and expected postoperative Catquest-9 SF score by each level of the variables. P values were noted as *P<0.05, **P<0.01, *** P<0.001.
‡The Kruskal Wallis test for variables with more than two levels and Wilcoxon-Mann Whitney test for variables with two levels were used for comparing the overall difference across groups of the variables between actual and expected postoperative Catquest-9 SF score. P values were noted as *P<0.05, **P<0.01, *** P<0.001.
¶ The expected improvement was achieved if actual post operative Catquest-9 SF score was equal to or more than expected postoperative score. Chi-square test or Fisher’s exact test (one or more than one cell frequency < = 5) was used to compare the proportion of the subjects achieving expected improvement between groups. P values were noted as *P<0.05, **P<0.01, *** P<0.001.
Preoperative difficulty, expected and actual postoperative improvement on the Catquest-9SF items by ocular characteristics (N = 174)§.
| Catquest-9SF score Median (IQR) | Subjects achieving expected improvement n (%)) | |||||
|---|---|---|---|---|---|---|
| Characteristics | Number of subjects | Preoperative | Expected postoperative | Actual postoperative | Difference of postoperative (Actual—Expected) | |
| >6/60 | 41 | 18 (14–21) | 28 (25–28) | 28 (26–28) | 0 (-1–2) | 27 (65.9) |
| >6/120 - ≤6/60 | 39 | 17 (9–21) | 28 (25–28) | 28 (24–28) | 0 (-3–0) | 23 (59.0) |
| ≤6/120 | 87 | 14 (10–19) | 28 (25–28) | 25 (23–28)*** | -1 (-3–1)* | 41 (47.1) |
| Yes | 5 | 14 (14–18) | 28 (28–28) | 23 (21–25) | -3 (-7–0) | 2 (40.0) |
| No | 169 | 16 (11–21) | 28 (25–28) | 27 (24–28)** | 0 (-2–0) | 93 (55.0) |
| Yes | 3 | 14 (10–16) | 24 (22–28) | 23 (21–28) | -3 (-5–6) | 1 (33.3) |
| No | 171 | 16 (11–21) | 28 (25–28) | 27 (24–28)** | 0 (-3–0) | 94 (55.0) |
| Yes | 14 | 13 (9–16) | 27.5 (23–28) | 21 (21–25)** | -2.5 (-6–0)** | 4 (28.6) |
| No | 160 | 16 (12–21) | 28 (25–28) | 27 (24.5–28)* | 0 (-2–0) | 91 (56.9) |
| Yes | 51 | 14 (12–19) | 28 (25–28) | 25 (21–28)*** | -1 (-4–0)*** | 19 (38.0)** |
| No | 123 | 17 (11–21) | 28 (25–28) | 28 (25–28) | 0 (-2–1) | 75 (61.5) |
| | ||||||
| ≤3 | 75 | 18 (14–21) | 28 (25–28) | 25 (23–28)** | -1 (-3–0) | 36 (48.0) |
| >3 - ≤5 | 77 | 14 (8–21) | 28 (25–28) | 27 (25–28) | 0 (-2–0) | 45 (58.4) |
| >5 | 20 | 15 (9–18.5) | 28 (27.5–28) | 28 (25.5–28) | 0 (-2–0) | 12 (60.0) |
| | ||||||
| ≤3 | 86 | 17 (14–21) | 28 (25–28) | 26 (23–28)** | -1 (-3–0) | 42 (48.8) |
| >3 - ≤4 | 54 | 16 (11–21) | 28 (27–28) | 26.5 (24–28)* | 0 (-2–0) | 31 (57.4) |
| >4 | 33 | 11 (7–18) | 28 (25–28) | 28 (26–28) | 0 (-1–1) | 21 (63.6) |
| Aspherical IOL | 94 | 15 (12–20) | 28 (24–28) | 25 (22–28)** | -0.5 (-3–0) | 47 (50.0) |
| Spherical IOL | 59 | 17 (11–21) | 28 (28–28) | 28 (27–28) | 0 (-1–0) | 34 (57.6) |
IQR = Inter Quartile Range LOCS = Lens opacities classification system NO = Nuclear opalescence C = Cortical cataract IOL = Intraocular lens.
§ Among 182 who had surgery, 174 (95.6%) persons had complete pre and post operative Catquest-9 SF data.
†The Wilcoxon signed rank sum test was used for comparing the difference between actual and expected postoperative Catquest-9 SF score by each level of the variables. P values were noted as *P<0.05, **P<0.01, *** P<0.001.
‡The Kruskal Wallis test for variables with more than two levels and Wilcoxon-Mann Whitney test for variables with two levels were used for comparing the overall difference across groups of the variables between actual and expected postoperative Catquest-9 SF score. P values were noted as *P<0.05, **P<0.01, *** P<0.001.
¶ The expected improvement was achieved if actual post operative Catquest-9 SF score was equal to or more than expected postoperative score. Chi-square test or Fisher’s exact test (one or more than one cell frequency < = 5) was used to compare the proportion of the subjects achieving expected improvement between groups. P values were noted as *P<0.05, **P<0.01, *** P<0.001.
Preoperative difficulty, expected and actual postoperative improvement on the Catquest-9SF items by functional characteristics (N = 174)*.
| Catquest-9SF score Median (IQR) | Subjects achieving expected improvement n (%) | ||||||
|---|---|---|---|---|---|---|---|
| Characteristics | Number of subjects | Preoperative | Expected postoperative | Actual postoperative | Actual postoperative | Difference of postoperative (Actual—Expected) | |
| Very difficult | 49 | 11 (7–15) | 28 (22–28) | 28 (25–28) | / | 0 (-1–2) | 36 (73.5) |
| Moderately difficult | 53 | 14 (11–18) | 28 (25–28) | 26 (24–28) | 16.5 (10–23) | -1 (-3–0) | 25 (47.2) |
| Little difficult | 19 | 19 (16–21) | 28 (27–28) | 26.5 (24–28) | 22 (21–24) | -1 (-3–0) | 26 (43.3) |
| Not difficult | 9 | 24 (20–28) | 28 (28–28) | 28 (26–28) | 28 (26–28) | 0 (-2–0) | 5 (55.6) |
| Spearman correlation (P-value) | -0.07 (0.35) | / | |||||
| Very dissatisfied | 83 | 14 (8–19) | 28 (25–28) | 26 (24–28) | 26.5 (25–28) | 0 (-3–0) | 43 (51.8) |
| Dissatisfied | 70 | 18 (14–21) | 28 (27–28) | 27 (25–28) | 21.5 (21–23) | 0 (-3–0) | 37 (52.9) |
| Satisfied | 17 | 15 (11–18) | 26 (24–28) | 28 (25–28) | 25 (21–26) | 0 (-1–1) | 12 (70.6) |
| Very satisfied | 4 | 16 (14–19.5) | 28 (26.5–28) | 28 (24.5–28) | 28 (27–28) | 0 (-3.5–1.5) | 3 (75.0) |
| Spearman correlation (P-value) | 0.02 (0.80) | 0.13 (0.09) | 0.09 (0.26) | / | |||
*Among 182 who had surgery, 174 (95.6%) persons had complete pre and post operative Catquest-9 SF data.
† In this column, trouble and satisfaction with vision was collected before surgery.
‡ In this column, trouble and satisfaction with vision was collected after surgery.
§ The expected improvement was achieved if actual post operative Catquest-9 SF score was equal to or more than expected postoperative score.
Expected and actual improvement in activities on the Catquest-9SF items (N = 174).
| % With difficulty before surgery | % With difficulty before surgery who expected to improve | % Who reported improvement after surgery among those with difficulty before surgery | % Who achieved expected level of improvement among those with difficulty before surgery | |
|---|---|---|---|---|
| 94.8 | 95.8 | 86.1 | 70.3 | |
| 86.2 | 86.9 | 88.7 | 79.3 | |
| 90.2 | 91.1 | 89.8 | 70.1 | |
| 86.2 | 86.9 | 90.0 | 81.3 | |
| 89.1 | 90.0 | 89.7 | 74.2 | |
| 90.8 | 91.7 | 91.8 | 76.6 | |
| 81.0 | 82.1 | 90.1 | 80.9 |
Linear regression of potential predictors of the discrepancy between actual and expected postoperative Catquest-9SF scores (N = 174).
| Simple Regression | Multiple Regression | |||
|---|---|---|---|---|
| β (95% CI) | P-value | β (95% CI) | P-value | |
| -0.008 (-0.06, 0.04) | 0.75 | |||
| 0.58 (-0.48, 1.65) | 0.28 | |||
| -0.06 (-1.16, 1.03) | 0.91 | |||
| 0.64 (-0.52, 1.79) | 0.28 | |||
| -0.44 (-4.55. 3.67) | 0.83 | |||
| -1.00 (-2.50, 0.49) | 0.19 | |||
| >6/60 | Reference | Reference | ||
| >6/120 - ≤6/60 | -1.02 (-2.57, 0.53) | 0.20 | -0.87 (-2.41, 0.68) | 0.27 |
| ≤6/120 | -0.98 (-2.33, 0.37) | 0.15 | ||
| ≤3 | Reference | |||
| >3 - ≤5 | 0.90 (-0.25, 2.04) | 0.12 | ||
| >5 | 0.50 (-1.27, 2.28) | 0.58 | ||
| ≤3 | Reference | Reference | ||
| >3 - ≤4 | 0.17 (-1.04, 1.38) | 0.78 | -0.07 (-1.29, 1.15) | 0.91 |
| >4 | 1.05 (-0.40, 2.49) | 0.15 | ||
| Aspherical IOL | -0.90 (-2.05, 0.24) | 0.12 | ||
| Spherical IOL | Reference | |||
AMD = Age-related macular degeneration LOCS = Lens opacities classification system.
NO = Nuclear opalescence C = Cortical cataract IOL = Intraocular lens.
* Variables with P<0.05 in simple regression were included in multiple regression analysis.
Ordinal logistic regression of potential predictors of the satisfaction with the surgery* (N = 172).
| Simple Regression | Multiple Regression | |||
|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | |
| 0.98 (0.95, 1.01) | 0.14 | |||
| 0.50 (0.22, 1.12) | 0.09 | |||
| 0.96 (0.43, 2.18) | 0.93 | |||
| 0.47 (0.22, 1.02) | 0.06 | |||
| 2.17 (0.20, 23.5) | 0.53 | |||
| 2.45 (0.91, 6.58) | 0.07 | |||
| 1.89 (0.78, 4.57) | 0.16 | |||
| >6/60 | Reference | Reference | ||
| >6/120 - ≤6/60 | 2.22 (0.51, 9.57) | 0.29 | ||
| ≤6/120 | 3.35 (0.93, 12.1) | 0.06 | ||
| ≤3 | Reference | Reference | ||
| >3 - ≤5 | 0.28 (0.07, 1.15) | 0.08 | ||
| >5 | 0.31 (0.07, 1.43) | 0.13 | 0.29 (0.04, 2.12) | 0.22 |
| ≤3 | Reference | |||
| >3 - ≤4 | 0.90 (0.39, 2.07) | 0.80 | 2.24 (0.57, 8.81) | 0.25 |
| >4 | 0.54 (0.04, 6.48) | 0.63 | ||
| Aspherical IOL | ||||
| Spherical IOL | Reference | |||
AMD = Age-related macular degeneration LOCS = Lens opacities classification system.
NO = Nuclear opalescence C = Cortical cataract IOL = Intraocular lens.
* Satisfaction with the surgery was coded as 1 = satisfied to 5 = very dissatisfied.
** Variables with P<0.05 in simple regression were included in multiple regression analysis. IOL type was not included in the multiple regression due to collinearity with NO (0.68) and C (0.61).