Literature DB >> 28067426

Non-Coding RNAs: The New Insight on Hypertrophic Scar.

Ling Chen1, Jingyun Li1, Qian Li1, Hui Yan1, Bei Zhou1, Yanli Gao1, Jun Li1.   

Abstract

Hypertrophic scarring (HS), a fibroproliferative disorder caused by abnormal wound healing after skin injury, is characterized by excessive deposition of extracellular matrix and invasive growth of fibroblasts. Numerous studies have reported that non-coding RNAs (ncRNAs) including microRNAs (miRNAs, miRs) and long non-coding RNAs (lncRNAs) play important roles in HS formation. Exploring non-coding RNA-based methods to treat scar would be instrumental for devising new effective therapies against scar. J. Cell. Biochem. 118: 1965-1968, 2017.
© 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Entities:  

Keywords:  HYPERTROPHIC SCAR; NON-CODING RNAs; lncRNAs; miRNAs

Mesh：

Substances：

Year:  2017        PMID： 28067426     DOI： 10.1002/jcb.25873

Source DB:  PubMed          Journal:  J Cell Biochem        ISSN： 0730-2312            Impact factor:   4.429


  14 in total

1.  MiR-3613-3p inhibits hypertrophic scar formation by down-regulating arginine and glutamate-rich 1.

Authors:  Lisha Li; Weiqiang Han; Yun Chen; Yuhua Chen
Journal:  Mol Cell Biochem       Date:  2020-11-09       Impact factor: 3.396

Review 2.  Circular RNAs: epigenetic regulators in cancerous and noncancerous skin diseases.

Authors:  Abbas Abi; Najmeh Farahani; Ghader Molavi; Seyed Mohammad Gheibi Hayat
Journal:  Cancer Gene Ther       Date:  2019-09-03       Impact factor: 5.987

3.  MicroRNA-494 targets PTEN and suppresses PI3K/AKT pathway to alleviate hypertrophic scar formation.

Authors:  Ting He; Yue Zhang; Yang Liu; Hongtao Wang; Wanfu Zhang; Jiaqi Liu; Na Li; Yan Li; Luxu Wang; Songtao Xie; Dahai Hu
Journal:  J Mol Histol       Date:  2019-05-08       Impact factor: 2.611

Review 4.  Targeting microRNA for improved skin health.

Authors:  Xi Li; Sakthi Ponandai-Srinivasan; Kutty Selva Nandakumar; Susanne Fabre; Ning Xu Landén; Alain Mavon; Ia Khmaladze
Journal:  Health Sci Rep       Date:  2021-10-12

5.  Knockdown of lncRNA-NEAT1 expression inhibits hypoxia-induced scar fibroblast proliferation through regulation of the miR-488-3p/COL3A1 axis.

Authors:  Huan Xu; Xuesong Guo; Yu Tian; Junqing Wang
Journal:  Exp Ther Med       Date:  2022-05-13       Impact factor: 2.751

6.  Identification of crucial noncoding RNAs and mRNAs in hypertrophic scars via RNA sequencing.

Authors:  Xiaodong Li; Zeliang He; Julei Zhang; Yan Han
Journal:  FEBS Open Bio       Date:  2021-05-12       Impact factor: 2.693

7.  High‑throughput sequencing reveals differentially expressed lncRNAs and circRNAs, and their associated functional network, in human hypertrophic scars.

Authors:  Min Li; Jian Wang; Dewu Liu; Heping Huang
Journal:  Mol Med Rep       Date:  2018-10-15       Impact factor: 2.952

8.  lncRNA PAPPA-AS1 Induces the Development of Hypertrophic Scar by Upregulating TLR4 through Interacting with TAF15.

Authors:  Pengju Fan; Yongjie Wang; Jingjing Li; Man Fang
Journal:  Mediators Inflamm       Date:  2021-07-03       Impact factor: 4.711

9.  Aberrantly expressed long noncoding RNAs in hypertrophic scar fibroblasts in vitro: A microarray study.

Authors:  Longxiang Tu; Qi Huang; Shangfeng Fu; Dewu Liu
Journal:  Int J Mol Med       Date:  2018-01-26       Impact factor: 4.101

10.  MicroRNA‑486‑5p inhibits the growth of human hypertrophic scar fibroblasts by regulating Smad2 expression.

Authors:  Yingying Shi; Luping Wang; Pijun Yu; Yi Liu; Wei Chen
Journal:  Mol Med Rep       Date:  2019-04-24       Impact factor: 2.952
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