Taemin Oh1, Renaud Lafage2, Virginie Lafage2, Themistocles Protopsaltis3, Vincent Challier3, Christopher Shaffrey4, Han Jo Kim2, Paul Arnold5, Jens Chapman6, Frank Schwab2, Eric Massicotte7, Tim Yoon8, Shay Bess3, Michael Fehlings7, Justin Smith4, Christopher Ames9. 1. Department of Neurological Surgery, UCSF, San Francisco, California, USA. Electronic address: taemin.oh@ucsf.edu. 2. Hospital for Special Surgery, Department of Orthopaedic Surgery, New York, New York, USA. 3. Department of Orthopaedic Surgery, NYU Langone Medical Center, New York, New York, USA. 4. Department of Neurological Surgery, University of Virginia, Charlottesville, New York, USA. 5. Department of Neurological Surgery, The University of Kansas Hospital, Kansas City, Kansas, USA. 6. Swedish Medical Center, Department of Orthopaedic Surgery, Seattle, Washington, USA. 7. Department of Neurological Surgery, University of Toronto, Toronto, Ontario, Canada. 8. Department of Orthopaedic Surgery, Emory University School of Medicine, Atlanta, Georgia, USA. 9. Department of Neurological Surgery, UCSF, San Francisco, California, USA.
Abstract
BACKGROUND: Although cervical spondylotic myelopathy (CSM) can be devastating, its relative impact on general health remains unclear. Patient responses to the Short Form Survey 36-Health Survey (SF-36) Physical Component Summary (PCS)/Mental Component Summary (MCS) were compared between CSM and other diseases to evaluate their respective impacts on quality of life. The objective of this study was to compare SF-36 PCS/MCS scores in CSM with population and disease-specific norms. METHODS: Retrospective analysis of a prospective, multicenter AOSpine North American CSM Study database. Inclusion criteria were symptomatic disease, age older than 18 years, cord compression on magnetic resonance imaging or computed tomography myelography, and baseline SF-36 values. SF-36 PCS/MCS scores in CSM were compared with national normative values and disease-specific norms using Student t test. Analysis of variance was used to assess differences across age groups and offsets from age-matched controls. Threshold for significance was P < 0.05. RESULTS: There were 285 patients who met the inclusion criteria. The mean age was 56.6 ± 12.0 years, with male predominance (60%). SF-36 scores revealed significant baseline disability (PCS: 34.5 ± 9.8; MCS: 41.5 ± 14.4). Although there were no differences across age groups, when compared with age-matched normative data, younger patients had a larger PCS offset than older patients. CSM caused worse physical disability than most diseases except heart failure. Only back pain/sciatica induced worse mental disability. CONCLUSIONS: CSM affects quality of life to an extent greater than diabetes or cancer. Although mean impact of CSM does not vary with age, younger patients suffer from greater differences in baseline function. This study highlights the impact of myelopathy on patient function, particularly among younger age groups, and suggests that CSM merits a similar caliber of healthy policy attention as more well-studied diseases. Published by Elsevier Inc.
BACKGROUND: Although cervical spondylotic myelopathy (CSM) can be devastating, its relative impact on general health remains unclear. Patient responses to the Short Form Survey 36-Health Survey (SF-36) Physical Component Summary (PCS)/Mental Component Summary (MCS) were compared between CSM and other diseases to evaluate their respective impacts on quality of life. The objective of this study was to compare SF-36 PCS/MCS scores in CSM with population and disease-specific norms. METHODS: Retrospective analysis of a prospective, multicenter AOSpine North American CSM Study database. Inclusion criteria were symptomatic disease, age older than 18 years, cord compression on magnetic resonance imaging or computed tomography myelography, and baseline SF-36 values. SF-36 PCS/MCS scores in CSM were compared with national normative values and disease-specific norms using Student t test. Analysis of variance was used to assess differences across age groups and offsets from age-matched controls. Threshold for significance was P < 0.05. RESULTS: There were 285 patients who met the inclusion criteria. The mean age was 56.6 ± 12.0 years, with male predominance (60%). SF-36 scores revealed significant baseline disability (PCS: 34.5 ± 9.8; MCS: 41.5 ± 14.4). Although there were no differences across age groups, when compared with age-matched normative data, younger patients had a larger PCS offset than older patients. CSM caused worse physical disability than most diseases except heart failure. Only back pain/sciatica induced worse mental disability. CONCLUSIONS: CSM affects quality of life to an extent greater than diabetes or cancer. Although mean impact of CSM does not vary with age, younger patients suffer from greater differences in baseline function. This study highlights the impact of myelopathy on patient function, particularly among younger age groups, and suggests that CSM merits a similar caliber of healthy policy attention as more well-studied diseases. Published by Elsevier Inc.
Entities:
Keywords:
Cervical spondylotic myelopathy; Degenerative; Disability; Health care; Outcomes; Quality of life; SF-36
Authors: Jan Valošek; Petr Bednařík; Miloš Keřkovský; Petr Hluštík; Josef Bednařík; Alena Svatkova Journal: J Clin Med Date: 2022-04-20 Impact factor: 4.964
Authors: Benjamin M Davies; Danyal Z Khan; Oliver D Mowforth; Angus G K McNair; Toto Gronlund; Angelos G Kolias; Lindsay Tetreault; Michelle L Starkey; Iwan Sadler; Ellen Sarewitz; Delphine Houlton; Julia Carter; Sukhvinder Kalsi-Ryan; Bizhan Aarabi; Brian K Kwon; Shekar N Kurpad; James Harrop; Jefferson R Wilson; Robert Grossman; Armin Curt; Michael G Fehlings; Mark R N Kotter Journal: Global Spine J Date: 2019-05-08