Wenqi Wu1, Zhou Yang1, Changbao Xu2, Xiaojian Gu3, Sixing Yang4, Songbai Liao5, Rongjiang Wang6, Wenxi Gao7, Zhangqun Ye8, Guohua Zeng9. 1. Department of Urology, Minimally Invasive Surgery Center, First Affiliated Hospital of Guangzhou Medical University and Guangdong Key Laboratory of Urology, Guangzhou, China. 2. Department of Urology, Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China. 3. Department of Urology, Chinese Medicine Hospital of Jiangsu Province, Nanjing, China. 4. Department of Urology, People's Hospital of Wuhan University, Wuhan, China. 5. Department of Urology, 181 Hospital of Chinese People's Liberation Army, Guilin, China. 6. Department of Urology, People's Hospital of Huzhou, Huzhou, China. 7. Department of Urology, Chinese Medicine Hospital of Hubei Province, Wuhan, China. 8. Department of Urology, Tongji Hospital of Huazhong Science and Technology University, Wuhan, China. Electronic address: Zhangqun_ye@163.com. 9. Department of Urology, Minimally Invasive Surgery Center, First Affiliated Hospital of Guangzhou Medical University and Guangdong Key Laboratory of Urology, Guangzhou, China. Electronic address: gzgyzgh@vip.tom.com.
Abstract
PURPOSE: We assessed the efficacy and safety of external physical vibration lithecbole for the treatment of residual stones after retrograde intrarenal surgery. MATERIALS AND METHODS: A total of 173 patients (128 males and 45 females) were selected for study. All patients had residual fragments after retrograde intrarenal surgery for renal or upper ureteral stones. They were prospectively randomized into 2 groups. One group underwent external physical vibration lithecbole 1 week after retrograde intrarenal surgery and the other underwent only retrograde intrarenal surgery as the control group. Stone size and location, stone-free rate and complications were compared. RESULTS: Of 173 patients 87 (66 males and 21 females) were in the treatment group and 86 (62 males and 24 females) were in the control group. The stone-free rate in the treated and control groups 2 weeks after retrograde intrarenal surgery was 52.9% and 31.4%, at 3 weeks it was 71.3% and 51.2%, and at 5 weeks it was 89.7% and 59.3%, respectively (all p <0.05). The hematuria incidence 5 weeks after retrograde intrarenal surgery was 3.4% in the treated group compared to 20.9% in the control group (p <0.05). The incidence of positive urine leukocytes in the treated vs control groups was 4.6% vs 19.8% 3 weeks after retrograde intrarenal surgery and 3.4% vs 11.6% at 5 weeks (p <0.05). CONCLUSIONS:External physical vibration lithecbole as a supplement to retrograde intrarenal surgery was more effective than retrograde intrarenal surgery alone in terms of stone clearance speed, stone-free rate and patient compliance.
RCT Entities:
PURPOSE: We assessed the efficacy and safety of external physical vibration lithecbole for the treatment of residual stones after retrograde intrarenal surgery. MATERIALS AND METHODS: A total of 173 patients (128 males and 45 females) were selected for study. All patients had residual fragments after retrograde intrarenal surgery for renal or upper ureteral stones. They were prospectively randomized into 2 groups. One group underwent external physical vibration lithecbole 1 week after retrograde intrarenal surgery and the other underwent only retrograde intrarenal surgery as the control group. Stone size and location, stone-free rate and complications were compared. RESULTS: Of 173 patients 87 (66 males and 21 females) were in the treatment group and 86 (62 males and 24 females) were in the control group. The stone-free rate in the treated and control groups 2 weeks after retrograde intrarenal surgery was 52.9% and 31.4%, at 3 weeks it was 71.3% and 51.2%, and at 5 weeks it was 89.7% and 59.3%, respectively (all p <0.05). The hematuria incidence 5 weeks after retrograde intrarenal surgery was 3.4% in the treated group compared to 20.9% in the control group (p <0.05). The incidence of positive urine leukocytes in the treated vs control groups was 4.6% vs 19.8% 3 weeks after retrograde intrarenal surgery and 3.4% vs 11.6% at 5 weeks (p <0.05). CONCLUSIONS: External physical vibration lithecbole as a supplement to retrograde intrarenal surgery was more effective than retrograde intrarenal surgery alone in terms of stone clearance speed, stone-free rate and patient compliance.