Literature DB >> 28059591

Epigenetic modification in chromatin machinery and its deregulation in pediatric brain tumors: Insight into epigenetic therapies.

Eleonore Maury1,2, Rintaro Hashizume1,3.   

Abstract

Malignancies are characterized by the reprogramming of epigenetic patterns. This reprogramming includes gains or losses in DNA methylation and disruption of normal patterns of covalent histone modifications, which are associated with changes in chromatin remodeling processes. This review will focus on the mechanisms underlying this reprogramming and, specifically, on the role of histone modification in chromatin machinery and the modifications in epigenetic processes occurring in brain cancer, with a specific focus on epigenetic therapies for pediatric brain tumors.

Entities:  

Keywords:  Acetylation; DIPG; brain tumor; demethylase; epigenetic; histone; methylation; methyltransferase; pediatric

Mesh：

Substances：

Year:  2017        PMID： 28059591      PMCID： PMC5453195          DOI： 10.1080/15592294.2016.1278095

Source DB:  PubMed          Journal:  Epigenetics        ISSN： 1559-2294            Impact factor:   4.528


  145 in total

1.  Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.

Authors:  M Weller; T Gorlia; J G Cairncross; M J van den Bent; W Mason; K Belanger; A A Brandes; U Bogdahn; D R Macdonald; P Forsyth; A O Rossetti; D Lacombe; R-O Mirimanoff; C J Vecht; R Stupp
Journal:  Neurology       Date:  2011-08-31       Impact factor: 9.910

2.  Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma.

Authors:  Hendrik Witt; Stephen C Mack; Marina Ryzhova; Sebastian Bender; Martin Sill; Ruth Isserlin; Axel Benner; Thomas Hielscher; Till Milde; Marc Remke; David T W Jones; Paul A Northcott; Livia Garzia; Kelsey C Bertrand; Andrea Wittmann; Yuan Yao; Stephen S Roberts; Luca Massimi; Tim Van Meter; William A Weiss; Nalin Gupta; Wiesia Grajkowska; Boleslaw Lach; Yoon-Jae Cho; Andreas von Deimling; Andreas E Kulozik; Olaf Witt; Gary D Bader; Cynthia E Hawkins; Uri Tabori; Abhijit Guha; James T Rutka; Peter Lichter; Andrey Korshunov; Michael D Taylor; Stefan M Pfister
Journal:  Cancer Cell       Date:  2011-08-16       Impact factor: 31.743

Review 3.  Recent advances in neuroblastoma.

Authors:  John M Maris
Journal:  N Engl J Med       Date:  2010-06-10       Impact factor: 91.245

4.  EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation.

Authors:  Wendy Béguelin; Relja Popovic; Matt Teater; Yanwen Jiang; Karen L Bunting; Monica Rosen; Hao Shen; Shao Ning Yang; Ling Wang; Teresa Ezponda; Eva Martinez-Garcia; Haikuo Zhang; Yupeng Zheng; Sharad K Verma; Michael T McCabe; Heidi M Ott; Glenn S Van Aller; Ryan G Kruger; Yan Liu; Charles F McHugh; David W Scott; Young Rock Chung; Neil Kelleher; Rita Shaknovich; Caretha L Creasy; Randy D Gascoyne; Kwok-Kin Wong; Leandro Cerchietti; Ross L Levine; Omar Abdel-Wahab; Jonathan D Licht; Olivier Elemento; Ari M Melnick
Journal:  Cancer Cell       Date:  2013-05-13       Impact factor: 31.743

5.  Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing.

Authors:  Marcin Imielinski; Alice H Berger; Peter S Hammerman; Bryan Hernandez; Trevor J Pugh; Eran Hodis; Jeonghee Cho; James Suh; Marzia Capelletti; Andrey Sivachenko; Carrie Sougnez; Daniel Auclair; Michael S Lawrence; Petar Stojanov; Kristian Cibulskis; Kyusam Choi; Luc de Waal; Tanaz Sharifnia; Angela Brooks; Heidi Greulich; Shantanu Banerji; Thomas Zander; Danila Seidel; Frauke Leenders; Sascha Ansén; Corinna Ludwig; Walburga Engel-Riedel; Erich Stoelben; Jürgen Wolf; Chandra Goparju; Kristin Thompson; Wendy Winckler; David Kwiatkowski; Bruce E Johnson; Pasi A Jänne; Vincent A Miller; William Pao; William D Travis; Harvey I Pass; Stacey B Gabriel; Eric S Lander; Roman K Thomas; Levi A Garraway; Gad Getz; Matthew Meyerson
Journal:  Cell       Date:  2012-09-14       Impact factor: 41.582

Review 6.  Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer.

Authors:  Christoph Plass; Stefan M Pfister; Anders M Lindroth; Olga Bogatyrova; Rainer Claus; Peter Lichter
Journal:  Nat Rev Genet       Date:  2013-10-09       Impact factor: 53.242

Review 7.  Inhibitors of DNA Methylation, Histone Deacetylation, and Histone Demethylation: A Perfect Combination for Cancer Therapy.

Authors:  C A Zahnow; M Topper; M Stone; T Murray-Stewart; H Li; S B Baylin; R A Casero
Journal:  Adv Cancer Res       Date:  2016-03-02       Impact factor: 6.242

8.  Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.

Authors:  Mark A Dawson; Rab K Prinjha; Antje Dittmann; George Giotopoulos; Marcus Bantscheff; Wai-In Chan; Samuel C Robson; Chun-wa Chung; Carsten Hopf; Mikhail M Savitski; Carola Huthmacher; Emma Gudgin; Dave Lugo; Soren Beinke; Trevor D Chapman; Emma J Roberts; Peter E Soden; Kurt R Auger; Olivier Mirguet; Konstanze Doehner; Ruud Delwel; Alan K Burnett; Phillip Jeffrey; Gerard Drewes; Kevin Lee; Brian J P Huntly; Tony Kouzarides
Journal:  Nature       Date:  2011-10-02       Impact factor: 49.962

9.  A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.

Authors:  Laurens Kruidenier; Chun-wa Chung; Zhongjun Cheng; John Liddle; KaHing Che; Gerard Joberty; Marcus Bantscheff; Chas Bountra; Angela Bridges; Hawa Diallo; Dirk Eberhard; Sue Hutchinson; Emma Jones; Roy Katso; Melanie Leveridge; Palwinder K Mander; Julie Mosley; Cesar Ramirez-Molina; Paul Rowland; Christopher J Schofield; Robert J Sheppard; Julia E Smith; Catherine Swales; Robert Tanner; Pamela Thomas; Anthony Tumber; Gerard Drewes; Udo Oppermann; Dinshaw J Patel; Kevin Lee; David M Wilson
Journal:  Nature       Date:  2012-08-16       Impact factor: 49.962

10.  Integrative analysis of 111 reference human epigenomes.

Authors:  Anshul Kundaje; Wouter Meuleman; Jason Ernst; Misha Bilenky; Angela Yen; Alireza Heravi-Moussavi; Pouya Kheradpour; Zhizhuo Zhang; Jianrong Wang; Michael J Ziller; Viren Amin; John W Whitaker; Matthew D Schultz; Lucas D Ward; Abhishek Sarkar; Gerald Quon; Richard S Sandstrom; Matthew L Eaton; Yi-Chieh Wu; Andreas R Pfenning; Xinchen Wang; Melina Claussnitzer; Yaping Liu; Cristian Coarfa; R Alan Harris; Noam Shoresh; Charles B Epstein; Elizabeta Gjoneska; Danny Leung; Wei Xie; R David Hawkins; Ryan Lister; Chibo Hong; Philippe Gascard; Andrew J Mungall; Richard Moore; Eric Chuah; Angela Tam; Theresa K Canfield; R Scott Hansen; Rajinder Kaul; Peter J Sabo; Mukul S Bansal; Annaick Carles; Jesse R Dixon; Kai-How Farh; Soheil Feizi; Rosa Karlic; Ah-Ram Kim; Ashwinikumar Kulkarni; Daofeng Li; Rebecca Lowdon; GiNell Elliott; Tim R Mercer; Shane J Neph; Vitor Onuchic; Paz Polak; Nisha Rajagopal; Pradipta Ray; Richard C Sallari; Kyle T Siebenthall; Nicholas A Sinnott-Armstrong; Michael Stevens; Robert E Thurman; Jie Wu; Bo Zhang; Xin Zhou; Arthur E Beaudet; Laurie A Boyer; Philip L De Jager; Peggy J Farnham; Susan J Fisher; David Haussler; Steven J M Jones; Wei Li; Marco A Marra; Michael T McManus; Shamil Sunyaev; James A Thomson; Thea D Tlsty; Li-Huei Tsai; Wei Wang; Robert A Waterland; Michael Q Zhang; Lisa H Chadwick; Bradley E Bernstein; Joseph F Costello; Joseph R Ecker; Martin Hirst; Alexander Meissner; Aleksandar Milosavljevic; Bing Ren; John A Stamatoyannopoulos; Ting Wang; Manolis Kellis
Journal:  Nature       Date:  2015-02-19       Impact factor: 69.504
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  14 in total

1.  Radiosensitization by Histone H3 Demethylase Inhibition in Diffuse Intrinsic Pontine Glioma.

Authors:  Hiroaki Katagi; Nundia Louis; Dusten Unruh; Takahiro Sasaki; Xingyao He; Ali Zhang; Quanhong Ma; Andrea Piunti; Yosuke Shimazu; Jonathan B Lamano; Angel M Carcaboso; Xiao Tian; Andrei Seluanov; Vera Gorbunova; Kathryn L Laurie; Akihide Kondo; Nitin R Wadhwani; Rishi Lulla; Stewart Goldman; Sriram Venneti; Oren J Becher; Lihua Zou; Ali Shilatifard; Rintaro Hashizume
Journal:  Clin Cancer Res       Date:  2019-06-21       Impact factor: 12.531

Review 2.  Chromatin remodeling defects in pediatric brain tumors.

Authors:  Alexia Klonou; Danai Spiliotakopoulou; Marios S Themistocleous; Christina Piperi; Athanasios G Papavassiliou
Journal:  Ann Transl Med       Date:  2018-06

Review 3.  Targeting and Therapeutic Monitoring of H3K27M-Mutant Glioma.

Authors:  Kyle Wierzbicki; Karthik Ravi; Andrea Franson; Amy Bruzek; Evan Cantor; Micah Harris; Morgan J Homan; Bernard L Marini; Abed Rahman Kawakibi; Ramya Ravindran; Rodrigo Teodoro; Viveka Nand Yadav; Carl Koschmann
Journal:  Curr Oncol Rep       Date:  2020-02-06       Impact factor: 5.075

Review 4.  Molecular Genetics and Targeted Therapies for Paediatric High-grade Glioma.

Authors:  Kathrine S Rallis; Alan Mathew George; Anna Maria Wozniak; Carola Maria Bigogno; Barbara Chow; John Gerrard Hanrahan; Michail Sideris
Journal:  Cancer Genomics Proteomics       Date:  2022 Jul-Aug       Impact factor: 3.395

5.  H3K27me3 loss indicates an increased risk of recurrence in the Tübingen meningioma cohort.

Authors:  Felix Behling; Christina Fodi; Irina Gepfner-Tuma; Kristina Kaltenbach; Mirjam Renovanz; Frank Paulsen; Marco Skardelly; Jürgen Honegger; Marcos Tatagiba; Jens Schittenhelm; Ghazaleh Tabatabai
Journal:  Neuro Oncol       Date:  2021-08-02       Impact factor: 12.300

6.  REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature.

Authors:  Shavali Shaik; Bridget Kennis; Shinji Maegawa; Keri Schadler; Yang Yanwen; Keri Callegari; Rishi R Lulla; Stewart Goldman; Javad Nazarian; Veena Rajaram; Jason Fangusaro; Vidya Gopalakrishnan
Journal:  Oncotarget       Date:  2017-12-28

Review 7.  Association of Smoking, Alcohol Use, and Betel Quid Chewing with Epigenetic Aberrations in Cancers.

Authors:  Tong-Hong Wang; Shih-Min Hsia; Yin-Hwa Shih; Tzong-Ming Shieh
Journal:  Int J Mol Sci       Date:  2017-06-06       Impact factor: 5.923

8.  Epigenetic drugs: More than meets the eye.

Authors:  Manel Esteller
Journal:  Epigenetics       Date:  2017-05-04       Impact factor: 4.528

9.  KDM3B suppresses APL progression by restricting chromatin accessibility and facilitating the ATRA-mediated degradation of PML/RARα.

Authors:  Xinrui Wang; Huiyong Fan; Congling Xu; Guojuan Jiang; Haiwei Wang; Ji Zhang
Journal:  Cancer Cell Int       Date:  2019-10-04       Impact factor: 5.722

Review 10.  Radiosensitization in Pediatric High-Grade Glioma: Targets, Resistance and Developments.

Authors:  Dennis S Metselaar; Aimée du Chatinier; Iris Stuiver; Gertjan J L Kaspers; Esther Hulleman
Journal:  Front Oncol       Date:  2021-04-01       Impact factor: 6.244
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