| Literature DB >> 28058839 |
Yoseb Yu1, Kye Jung Shin1, Jae Hong Seo1.
Abstract
We have developed an efficient three-component tandem reaction for the synthesis of 3-(1,3-diarylallylidene)oxindoles combining three palladium-catalyzed reactions: the Sonogashira, Heck, and Suzuki-Miyaura reactions. This method allows a stereoselective approach to each (E)- and (Z)-isomer by ligand change and controlling the reaction temperature.Entities:
Year: 2017 PMID： 28058839 DOI： 10.1021/acs.joc.6b02909
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354