BACKGROUND: The purpose of this study was to characterize the repeatability of ectopic beats, defined by premature atrial contractions (PACs) and premature ventricular contractions (PVCs), on ambulatory electrocardiogram (aECG) monitoring and evaluate the effect of length of aECG monitoring on the repeatability estimates. METHODS: This analysis includes 95 randomly selected participants from the Atherosclerosis Risk in Communities Study (ARIC; 2011-2013). The participants wore a Holter monitor for two, 48-hr periods separated by a mean of 38 days following an identical, standardized protocol. We divided each 48-hr recording into 3-, 6-, 12-, and 24-hr recording periods and calculated intraclass correlation coefficients (ICCs) for PACs and PVCs and also as a percentage of the corresponding total of recorded beats per hour among these periods. RESULTS: All participants had ≥1 PAC during the 48-hr recordings, and only two participants had no PVCs. ICCs were >0.83 for all indices and recording lengths ≥12 hrs. ICCs were intermediate for 6-hr recordings (range 0.80-0.83) and lower for 3-hr recordings (range 0.74-0.80). The ratio of the between- to within-participant variation increased with recording length. CONCLUSION: Repeatability of PACs and PVCs was excellent for recording lengths of 6-24 hr and fair for 3 hr. Repeatability varies over shorter duration recordings within the 48-hr recording period, and thus the present results have implications for detection algorithms for ectopic beats and can facilitate epidemiologic and clinical applications in which knowledge of measurement variability and misclassification are needed.
BACKGROUND: The purpose of this study was to characterize the repeatability of ectopic beats, defined by premature atrial contractions (PACs) and premature ventricular contractions (PVCs), on ambulatory electrocardiogram (aECG) monitoring and evaluate the effect of length of aECG monitoring on the repeatability estimates. METHODS: This analysis includes 95 randomly selected participants from the Atherosclerosis Risk in Communities Study (ARIC; 2011-2013). The participants wore a Holter monitor for two, 48-hr periods separated by a mean of 38 days following an identical, standardized protocol. We divided each 48-hr recording into 3-, 6-, 12-, and 24-hr recording periods and calculated intraclass correlation coefficients (ICCs) for PACs and PVCs and also as a percentage of the corresponding total of recorded beats per hour among these periods. RESULTS: All participants had ≥1 PAC during the 48-hr recordings, and only two participants had no PVCs. ICCs were >0.83 for all indices and recording lengths ≥12 hrs. ICCs were intermediate for 6-hr recordings (range 0.80-0.83) and lower for 3-hr recordings (range 0.74-0.80). The ratio of the between- to within-participant variation increased with recording length. CONCLUSION: Repeatability of PACs and PVCs was excellent for recording lengths of 6-24 hr and fair for 3 hr. Repeatability varies over shorter duration recordings within the 48-hr recording period, and thus the present results have implications for detection algorithms for ectopic beats and can facilitate epidemiologic and clinical applications in which knowledge of measurement variability and misclassification are needed.
Authors: Michelle L Meyer; Elsayed Z Soliman; Lisa M Wruck; Thomas H Mosley; Lynne E Wagenknecht; Anna K Poon; Eric A Whitsel; Alvaro Alonso; Gerardo Heiss; Laura R Loehr Journal: Ann Noninvasive Electrocardiol Date: 2017-01-06 Impact factor: 1.468
Authors: Susan R Heckbert; Thomas R Austin; Paul N Jensen; James S Floyd; Bruce M Psaty; Elsayed Z Soliman; Richard A Kronmal Journal: J Electrocardiol Date: 2018-07-30 Impact factor: 1.438
Authors: Michelle L Meyer; Elsayed Z Soliman; Lisa M Wruck; Thomas H Mosley; Lynne E Wagenknecht; Anna K Poon; Eric A Whitsel; Alvaro Alonso; Gerardo Heiss; Laura R Loehr Journal: Ann Noninvasive Electrocardiol Date: 2017-01-06 Impact factor: 1.468
Authors: Felke Steijns; Máté I Tóth; Anthony Demolder; Lars E Larsen; Jana Desloovere; Marjolijn Renard; Robrecht Raedt; Patrick Segers; Julie De Backer; Patrick Sips Journal: Sensors (Basel) Date: 2020-07-10 Impact factor: 3.576
Authors: Melanie D Napier; Nora Franceschini; Rahul Gondalia; James D Stewart; Raúl Méndez-Giráldez; Colleen M Sitlani; Amanda A Seyerle; Heather M Highland; Yun Li; Kirk C Wilhelmsen; Song Yan; Qing Duan; Jeffrey Roach; Jie Yao; Xiuqing Guo; Kent D Taylor; Susan R Heckbert; Jerome I Rotter; Kari E North; Alexander P Reiner; Zhu-Ming Zhang; Lesley F Tinker; Duanping Liao; Cathy C Laurie; Stephanie M Gogarten; Henry J Lin; Jennifer A Brody; Traci M Bartz; Bruce M Psaty; Nona Sotoodehnia; Elsayed Z Soliman; Christy L Avery; Eric A Whitsel Journal: Sci Rep Date: 2018-04-04 Impact factor: 4.379