Literature DB >> 28058676

Enzymatic antioxidant system of endotheliocytes.

M G Sharapov1, R G Goncharov1, A E Gordeeva1, V I Novoselov1, O A Antonova2, A K Tikhaze2, V Z Lankin3.   

Abstract

It is shown that endothelial cells from human umbilical vein have a reduced activity and gene expression of the "classic" antioxidant enzymes (Cu,Zn-superoxide dismutase, catalase, and Se-containing glutathione peroxidase). At the same time, a high expression level of peroxiredoxin genes was identified in the same endothelial cells, which obviously indicates the predominant involvement of these enzymes in protecting the endothelium from the damaging effect of free radical peroxidation.

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Year:  2017        PMID： 28058676     DOI： 10.1134/S1607672916060090

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  12 in total

1.  Glutathione peroxidase protects against peroxynitrite-mediated oxidations. A new function for selenoproteins as peroxynitrite reductase.

Authors:  H Sies; V S Sharov; L O Klotz; K Briviba
Journal:  J Biol Chem       Date:  1997-10-31       Impact factor: 5.157

2.  Analyzing real-time PCR data by the comparative C(T) method.

Authors:  Thomas D Schmittgen; Kenneth J Livak
Journal:  Nat Protoc       Date:  2008       Impact factor: 13.491

3.  Oxidation of active center cysteine of bovine 1-Cys peroxiredoxin to the cysteine sulfenic acid form by peroxide and peroxynitrite.

Authors:  I V Peshenko; H Shichi
Journal:  Free Radic Biol Med       Date:  2001-08-01       Impact factor: 7.376

4.  [Effect of hyperoxia on superoxide dismutase and glutathione lipoperoxidase activity in mouse tissues].

Authors:  V Z Lankin; D B Vandyshev; A K Tikhaze; V A Kosykh; V D Pomoĭnetskiĭ
Journal:  Dokl Akad Nauk SSSR       Date:  1981

Review 5.  A primer on peroxiredoxin biochemistry.

Authors:  P Andrew Karplus
Journal:  Free Radic Biol Med       Date:  2014-10-19       Impact factor: 7.376

6.  Primary culture of endothelial cells from atherosclerotic human aorta. Part 1. Identification, morphological and ultrastructural characteristics of two endothelial cell subpopulations.

Authors:  A S Antonov; M A Nikolaeva; T S Klueva; V R Babaev; V B Bystrevskaya; N A Perov; V S Repin; V N Smirnov
Journal:  Atherosclerosis       Date:  1986-01       Impact factor: 5.162

7.  Characterization of a mammalian peroxiredoxin that contains one conserved cysteine.

Authors:  S W Kang; I C Baines; S G Rhee
Journal:  J Biol Chem       Date:  1998-03-13       Impact factor: 5.157

8.  Modified LDLs induce proliferation-mediated death of human vascular endothelial cells through MAPK pathway.

Authors:  Eugene O Apostolov; Alexei G Basnakian; Xiaoyan Yin; Ercan Ok; Sudhir V Shah
Journal:  Am J Physiol Heart Circ Physiol       Date:  2006-12-08       Impact factor: 4.733

9.  Oxidized LDL upregulates angiotensin II type 1 receptor expression in cultured human coronary artery endothelial cells: the potential role of transcription factor NF-kappaB.

Authors:  D Li; T Saldeen; F Romeo; J L Mehta
Journal:  Circulation       Date:  2000-10-17       Impact factor: 29.690

10.  The initiation of free radical peroxidation of low-density lipoproteins by glucose and its metabolite methylglyoxal: a common molecular mechanism of vascular wall injure in atherosclerosis and diabetes.

Authors:  Vadim Lankin; Galina Konovalova; Alla Tikhaze; Konstantin Shumaev; Elena Kumskova; Margus Viigimaa
Journal:  Mol Cell Biochem       Date:  2014-07-05       Impact factor: 3.396
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  5 in total

1.  Natural Dicarbonyls Inhibit Peroxidase Activity of Peroxiredoxins.

Authors:  V Z Lankin; M G Sharapov; R G Goncharov; A K Tikhaze; V I Novoselov
Journal:  Dokl Biochem Biophys       Date:  2019-06-14       Impact factor: 0.788

2.  Influence of electromagnetic waves, with maxima in the green or red range, on the morphofunctional properties of multipotent stem cells.

Authors:  A S Chernov; D A Reshetnikov; G K Ristsov; Yu A Kovalitskaya; A M Ermakov; A A Manokhin; A V Simakin; R G Vasilov; S V Gudkov
Journal:  J Biol Phys       Date:  2019-10-08       Impact factor: 1.365

Review 3.  Dicarbonyl-Dependent Modification of LDL as a Key Factor of Endothelial Dysfunction and Atherosclerotic Vascular Wall Damage.

Authors:  Vadim Z Lankin; Alla K Tikhaze; Arthur M Melkumyants
Journal:  Antioxidants (Basel)       Date:  2022-08-12

Review 4.  Reductive Stress in Inflammation-Associated Diseases and the Pro-Oxidant Effect of Antioxidant Agents.

Authors:  Israel Pérez-Torres; Verónica Guarner-Lans; María Esther Rubio-Ruiz
Journal:  Int J Mol Sci       Date:  2017-10-05       Impact factor: 5.923

Review 5.  Oxidative, Reductive, and Nitrosative Stress Effects on Epigenetics and on Posttranslational Modification of Enzymes in Cardiometabolic Diseases.

Authors:  I Pérez-Torres; M E Soto; V Castrejón-Tellez; M E Rubio-Ruiz; L Manzano Pech; V Guarner-Lans
Journal:  Oxid Med Cell Longev       Date:  2020-10-30       Impact factor: 6.543
  5 in total

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