Literature DB >> 28058523

Convenient access to 5-arylisoindolo[2,1- α]quinolin-11(6a H)-ones.

Melissa O'Brien1, Rachael Weagle1, Donald Corkum1, Minati Kuanar1, Prabhu P Mohapatra1, Amitabh Jha2.   

Abstract

Substituted isoindoloquinolinones were obtained from N-aryl-3-hydroxyisoindolinones and aryl alkynes under Lewis acid-catalyzed conditions in 30-99% yields.

Entities:  

Keywords:  Aryl alkynes; Inverse electron demand cycloaddition; Lewis acid; N-Acyliminium ion; N-Aryl-3-hydroxyisoindolinones

Mesh：

Substances：

Year:  2017        PMID： 28058523     DOI： 10.1007/s11030-016-9718-3

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  4 in total

1.  Synthesis and inhibitory activity of novel tri- and tetracyclic quinolines against topoisomerases.

Authors:  Z Sui; J Altom; V N Nguyen; J Fernandez; J I Bernstein; J J Hiliard; J F Barrett; B L Podlogar; K A Ohemeng
Journal:  Bioorg Med Chem       Date:  1998-06       Impact factor: 3.641

2.  Relay catalytic branching cascade: a technique to access diverse molecular scaffolds.

Authors:  Nitin T Patil; Valmik S Shinde; Balasubramanian Sridhar
Journal:  Angew Chem Int Ed Engl       Date:  2013-01-17       Impact factor: 15.336

3.  Povarov-reductive amination cascade to access 6-aminoquinolines and anthrazolines.

Authors:  Kasiviswanadharaju Pericherla; Anil Kumar; Amitabh Jha
Journal:  Org Lett       Date:  2013-07-26       Impact factor: 6.005

4.  Synthesis of isoindolo[2,1-a]quinoline derivatives and their effects on N2-induced hypoxia.

Authors:  Y Ishihara; Y Kiyota; G Goto
Journal:  Chem Pharm Bull (Tokyo)       Date:  1990-11       Impact factor: 1.645
  4 in total
  1 in total

1.  Synthesis of dihydroisoindolo[2,1-a]quinolin-11-ones, their in silico ADMET properties and in vitro antitumor activities.

Authors:  Diego R Merchán-Arenas; Felipe Sojo; Francisco Arvelo; Vladimir V Kouznetsov
Journal:  RSC Adv       Date:  2020-11-19       Impact factor: 4.036
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.