Literature DB >> 28057685

RImmPort: an R/Bioconductor package that enables ready-for-analysis immunology research data.

Ravi D Shankar1, Sanchita Bhattacharya2, Chethan Jujjavarapu2, Sandra Andorf1, Jeffery A Wiser3, Atul J Butte2.   

Abstract

Summary: : Open access to raw clinical and molecular data related to immunological studies has created a tremendous opportunity for data-driven science. We have developed RImmPort that prepares NIAID-funded research study datasets in ImmPort (immport.org) for analysis in R. RImmPort comprises of three main components: (i) a specification of R classes that encapsulate study data, (ii) foundational methods to load data of a specific study and (iii) generic methods to slice and dice data across different dimensions in one or more studies. Furthermore, RImmPort supports open formalisms, such as CDISC standards on the open source bioinformatics platform Bioconductor, to ensure that ImmPort curated study datasets are seamlessly accessible and ready for analysis, thus enabling innovative bioinformatics research in immunology. Availability and Implementation: RImmPort is available as part of Bioconductor (bioconductor.org/packages/RImmPort). Contact: rshankar@stanford.edu. Supplementary information: Supplementary data are available at Bioinformatics online.
© The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

Mesh:

Year:  2017        PMID: 28057685      PMCID: PMC6041747          DOI: 10.1093/bioinformatics/btw719

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  4 in total

1.  ImmPort: disseminating data to the public for the future of immunology.

Authors:  Sanchita Bhattacharya; Sandra Andorf; Linda Gomes; Patrick Dunn; Henry Schaefer; Joan Pontius; Patty Berger; Vince Desborough; Tom Smith; John Campbell; Elizabeth Thomson; Ruth Monteiro; Patricia Guimaraes; Bryan Walters; Jeff Wiser; Atul J Butte
Journal:  Immunol Res       Date:  2014-05       Impact factor: 2.829

2.  Strengthening Research through Data Sharing.

Authors:  Elizabeth Warren
Journal:  N Engl J Med       Date:  2016-08-04       Impact factor: 91.245

3.  Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis.

Authors:  Thomas B Casale; William W Busse; Joel N Kline; Zuhair K Ballas; Mark H Moss; Robert G Townley; Masoud Mokhtarani; Vicki Seyfert-Margolis; Adam Asare; Kirk Bateman; Yamo Deniz
Journal:  J Allergy Clin Immunol       Date:  2005-12-02       Impact factor: 10.793

Review 4.  Novel technologies and emerging biomarkers for personalized cancer immunotherapy.

Authors:  Jianda Yuan; Priti S Hegde; Raphael Clynes; Periklis G Foukas; Alexandre Harari; Thomas O Kleen; Pia Kvistborg; Cristina Maccalli; Holden T Maecker; David B Page; Harlan Robins; Wenru Song; Edward C Stack; Ena Wang; Theresa L Whiteside; Yingdong Zhao; Heinz Zwierzina; Lisa H Butterfield; Bernard A Fox
Journal:  J Immunother Cancer       Date:  2016-01-19       Impact factor: 13.751

  4 in total
  3 in total

1.  Screening of key genes associated with m6A methylation in diabetic nephropathy patients by CIBERSORT and weighted gene coexpression network analysis.

Authors:  Shaohua Yin; Wen Li; Junjie Wang; Han Wu; Ji Hu; Yu Feng
Journal:  Am J Transl Res       Date:  2022-04-15       Impact factor: 3.940

2.  VaximmutorDB: A Web-Based Vaccine Immune Factor Database and Its Application for Understanding Vaccine-Induced Immune Mechanisms.

Authors:  Kimberly Berke; Peter Sun; Edison Ong; Nasim Sanati; Anthony Huffman; Timothy Brunson; Fred Loney; Joseph Ostrow; Rebecca Racz; Bin Zhao; Zuoshuang Xiang; Anna Maria Masci; Jie Zheng; Guanming Wu; Yongqun He
Journal:  Front Immunol       Date:  2021-03-12       Impact factor: 7.561

3.  ImmPort, toward repurposing of open access immunological assay data for translational and clinical research.

Authors:  Sanchita Bhattacharya; Patrick Dunn; Cristel G Thomas; Barry Smith; Henry Schaefer; Jieming Chen; Zicheng Hu; Kelly A Zalocusky; Ravi D Shankar; Shai S Shen-Orr; Elizabeth Thomson; Jeffrey Wiser; Atul J Butte
Journal:  Sci Data       Date:  2018-02-27       Impact factor: 6.444

  3 in total

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