Sara Sammallahti1,2,3, Kati Heinonen1, Sture Andersson2, Marius Lahti1,4, Sami Pirkola3,5, Jari Lahti1,6, Anu-Katriina Pesonen1, Aulikki Lano2, Dieter Wolke7, Johan G Eriksson3,8,9,10, Eero Kajantie2,3,11, Katri Raikkonen1. 1. Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland. 2. Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland. 3. National Institute for Health and Welfare, Helsinki, Finland. 4. University BHF Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK. 5. School of Health Sciences, University of Tampere and Tampere University Hospital, Tampere, Finland. 6. Helsinki Collegium for Advanced Studies, Helsinki, Finland. 7. Department of Psychology, University of Warwick, Coventry, UK. 8. Folkhälsan Research Center, Helsinki, Finland. 9. Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. 10. Vasa Central Hospital, Vasa, Finland. 11. Department of Obstetrics and Gynecology, Oulu University Hospital and University of Oulu, Oulu, Finland.
Abstract
BACKGROUND: Late-preterm birth (at 340⁄7-366⁄7 wk gestation) increases the risk of early growth faltering, poorer neurocognitive functioning, and lower socio-economic attainment. Among early-preterm individuals, faster early growth benefits neurodevelopment, but it remains unknown whether these benefits extend to late-preterm individuals. METHODS: In 108 late-preterm individuals, we examined if weight, head, or length growth between birth, 5 and 20 months' corrected age, and 56 mo, predicted grade point average and special education in comprehensive school, or neurocognitive abilities and psychiatric diagnoses/symptoms at 24-26 y of age. RESULTS: For every 1 SD faster weight and head growth from birth to 5 mo, and head growth from 5 to 20 mo, participants had 0.19-0.41 SD units higher IQ, executive functioning score, and grade point average (95% confidence intervals (CI) 0.002-0.59 SD), and lower odds of special education (odds ratio (OR) = 0.49-0.59, 95% CIs 0.28-0.97), after adjusting for sex, gestational age, follow-up age, and parental education. Faster head growth from 20 to 56 mo was associated with less internalizing problems; otherwise we found no consistent associations with mental health outcomes. CONCLUSION: Faster growth during the critical early period after late-preterm birth is associated with better adult neurocognitive functioning, but not consistently with mental health outcomes.
BACKGROUND: Late-preterm birth (at 340⁄7-366⁄7 wk gestation) increases the risk of early growth faltering, poorer neurocognitive functioning, and lower socio-economic attainment. Among early-preterm individuals, faster early growth benefits neurodevelopment, but it remains unknown whether these benefits extend to late-preterm individuals. METHODS: In 108 late-preterm individuals, we examined if weight, head, or length growth between birth, 5 and 20 months' corrected age, and 56 mo, predicted grade point average and special education in comprehensive school, or neurocognitive abilities and psychiatric diagnoses/symptoms at 24-26 y of age. RESULTS: For every 1 SD faster weight and head growth from birth to 5 mo, and head growth from 5 to 20 mo, participants had 0.19-0.41 SD units higher IQ, executive functioning score, and grade point average (95% confidence intervals (CI) 0.002-0.59 SD), and lower odds of special education (odds ratio (OR) = 0.49-0.59, 95% CIs 0.28-0.97), after adjusting for sex, gestational age, follow-up age, and parental education. Faster head growth from 20 to 56 mo was associated with less internalizing problems; otherwise we found no consistent associations with mental health outcomes. CONCLUSION: Faster growth during the critical early period after late-preterm birth is associated with better adult neurocognitive functioning, but not consistently with mental health outcomes.
Authors: Andreas Kakaroukas; Marieke Abrahamse-Berkeveld; Louise Hayes; Richard J Q McNally; Janet E Berrington; Ruurd M van Elburg; Nicholas D Embleton Journal: Pediatr Res Date: 2022-10-01 Impact factor: 3.953
Authors: Patrícia P Silveira; Irina Pokhvisneva; Hélène Gaudreau; Anne Rifkin-Graboi; Birit F P Broekman; Meir Steiner; Robert Levitan; Carine Parent; Josie Diorio; Michael J Meaney Journal: Sci Rep Date: 2018-09-12 Impact factor: 4.379