Literature DB >> 28055294

What determines the magnitude of cellular response for activation of G protein-coupled receptors?

Sebastian G B Furness1, Denise Wootten1, Patrick M Sexton1.   

Abstract

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Year:  2017        PMID： 28055294      PMCID： PMC5351919          DOI： 10.1080/15384101.2016.1271634

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  5 in total

1.  The energy landscapes and motions of proteins.

Authors:  H Frauenfelder; S G Sligar; P G Wolynes
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2.  Ligand-Dependent Modulation of G Protein Conformation Alters Drug Efficacy.

Authors:  Sebastian George Barton Furness; Yi-Lynn Liang; Cameron James Nowell; Michelle Louise Halls; Peter John Wookey; Emma Dal Maso; Asuka Inoue; Arthur Christopoulos; Denise Wootten; Patrick Michael Sexton
Journal:  Cell       Date:  2016-10-06       Impact factor: 41.582

Review 3.  Biased agonism at G protein-coupled receptors: the promise and the challenges--a medicinal chemistry perspective.

Authors:  Jeremy Shonberg; Laura Lopez; Peter J Scammells; Arthur Christopoulos; Ben Capuano; J Robert Lane
Journal:  Med Res Rev       Date:  2014-05-05       Impact factor: 12.944

4.  The role of ligands on the equilibria between functional states of a G protein-coupled receptor.

Authors:  Tae Hun Kim; Ka Young Chung; Aashish Manglik; Alexandar L Hansen; Ron O Dror; Thomas J Mildorf; David E Shaw; Brian K Kobilka; R Scott Prosser
Journal:  J Am Chem Soc       Date:  2013-06-14       Impact factor: 15.419

5.  The conformational signature of β-arrestin2 predicts its trafficking and signalling functions.

Authors:  Mi-Hye Lee; Kathryn M Appleton; Erik G Strungs; Joshua Y Kwon; Thomas A Morinelli; Yuri K Peterson; Stephane A Laporte; Louis M Luttrell
Journal:  Nature       Date:  2016-03-23       Impact factor: 49.962
  5 in total

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