Literature DB >> 28045631

Head and Neck Cancer.

Peter F Svider1, Michael A Blasco1, S Naweed Raza1,2, Mahdi Shkoukani1,2,3, Ammar Sukari2,4, George H Yoo1,2, Adam J Folbe1,2, Ho-Sheng Lin1,2,3, Andrew M Fribley1,2,5,6.   

Abstract

Despite a considerable expansion in our therapeutic repertoire for management of other malignancies, mortality from head and neck cancer (HNC) has not significantly improved in recent decades. Upon normalizing National Institutes of Health-awarded R01 and R01-equivalent grants by incidence, thyroid cancer ($214) and HNC ($1329) received the fewest funding dollars. Upon adjusting funding totals by mortality, HNC was 7th out of 9 cancers evaluated ($6138). These findings highlight HNC as an underfunded disease versus other cancers. As data detailing grant applications (including unsuccessful grants) are not publicly available, it is not clear if these disparities stem from fewer applications or fewer opportunities. Our hope is that this commentary will spur further investigation into strategies to increase HNC inquiry and funding for trainees as well as early-stage and established investigators.

Entities:  

Keywords:  National Institutes of Health; head and neck cancer; head and neck squamous cell carcinoma

Mesh:

Year:  2016        PMID: 28045631     DOI: 10.1177/0194599816674672

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  9 in total

1.  A comprehensive investigation using meta-analysis and bioinformatics on miR-34a-5p expression and its potential role in head and neck squamous cell carcinoma.

Authors:  Jixi Li; Kang Liu; Tingting Zhang; Zhendong Yang; Rensheng Wang; Gang Chen; Min Kang
Journal:  Am J Transl Res       Date:  2018-08-15       Impact factor: 4.060

Review 2.  Targeting the unfolded protein response in head and neck and oral cavity cancers.

Authors:  Daniel W Cole; Peter F Svider; Kerolos G Shenouda; Paul B Lee; Nicholas G Yoo; Thomas M McLeod; Sean A Mutchnick; George H Yoo; Randal J Kaufman; Michael U Callaghan; Andrew M Fribley
Journal:  Exp Cell Res       Date:  2019-05-07       Impact factor: 3.905

3.  Regulation of VEGFA, KRAS, and NFE2L2 Oncogenes by MicroRNAs in Head and Neck Cancer.

Authors:  Caroline Izak Cuzziol; Ludimila Leite Marzochi; Vitória Scavacini Possebon; Rosa Sayoko Kawasaki-Oyama; Marlon Fraga Mattos; Vilson Serafim Junior; Letícia Antunes Muniz Ferreira; Érika Cristina Pavarino; Márcia Maria Urbanin Castanhole-Nunes; Eny Maria Goloni-Bertollo
Journal:  Int J Mol Sci       Date:  2022-07-05       Impact factor: 6.208

4.  NIH Funding of Researchers in Surgery: Decreased Career Development Awards Over Time.

Authors:  Mary Smithson; M Chandler McLeod; Dan I Chu; Greg Kennedy; Melanie Morris; Herbert Chen; Karin M Hardiman
Journal:  J Surg Res       Date:  2021-05-08       Impact factor: 2.417

Review 5.  Single-cell genomic analysis of head and neck squamous cell carcinoma.

Authors:  Andres Stucky; Parish P Sedghizadeh; Susan Mahabady; Xuelian Chen; Cheng Zhang; Gang Zhang; Xi Zhang; Jiang F Zhong
Journal:  Oncotarget       Date:  2017-05-19

6.  Silencing the lncRNA NORAD inhibits EMT of head and neck squamous cell carcinoma stem cells via miR‑26a‑5p.

Authors:  Weiming Hu; Yong Zhao; Lizhong Su; Zuliang Wu; Wenjing Jiang; Xiaoze Jiang; Ming Liu
Journal:  Mol Med Rep       Date:  2021-08-26       Impact factor: 2.952

7.  Diagnostic and Prognostic Value of MicroRNAs in Metastasis and Recurrence of Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.

Authors:  Ke Qiu; Yao Song; Yufang Rao; Qiurui Liu; Danni Cheng; Wendu Pang; Jianjun Ren; Yu Zhao
Journal:  Front Oncol       Date:  2021-09-27       Impact factor: 6.244

8.  Expression of chemokine CXCL8/9/10/11/13 and its prognostic significance in head and neck cancer.

Authors:  Zhenyu Zhao; Yuyu Ma; Jie Lv; Naifeisha Maimaiti; Jingyi Zhang; Madinaimu Aibibula; Zhongcheng Gong; Bin Ling
Journal:  Medicine (Baltimore)       Date:  2022-07-29       Impact factor: 1.817

9.  Accelerated vs. conventionally fractionated adjuvant radiotherapy in high-risk head and neck cancer: a meta-analysis.

Authors:  Christiane Matuschek; Jan Haussmann; Edwin Bölke; Stephan Gripp; Patrick J Schuler; Bálint Tamaskovics; Peter Arne Gerber; Freddy-Joel Djiepmo-Njanang; Kai Kammers; Christian Plettenberg; Bahar Anooshahr; Klaus Orth; Wilfried Budach
Journal:  Radiat Oncol       Date:  2018-10-04       Impact factor: 3.481

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.