Literature DB >> 2804552

Increase in gastric secretion induced by 2-deoxy-D-glucose is impaired in capsaicin pretreated rats.

S Evangelista1, P Santicioli, C A Maggi, A Meli.   

Abstract

Gastric acid secretion was determined following intravenous administration of 2-deoxy-D-glucose (2-DG; 60 mg kg-1) or electrical stimulation of the vagus nerve in urethane-anaesthetized rats pretreated when newborn with either capsaicin or the vehicle. The secretory response to 2-DG was substantially reduced in the capsaicin pretreated rats, while that induced by electrical vagal stimulation (1 mA, 1 ms. 3 Hz) was unaffected. These results suggest that capsaicin-sensitive fibres are involved in the afferent branch of the reflex response activated by 2-DG to stimulate gastric acid secretion.

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Year:  1989        PMID： 2804552      PMCID： PMC1854652          DOI： 10.1111/j.1476-5381.1989.tb16858.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  8 in total

1.  Continuous recording of acid gastric secretion in the rat.

Authors:  M N GHOSH; H O SCHILD
Journal:  Br J Pharmacol Chemother       Date:  1958-03

2.  Vagal gastric secretory stimulation by 2-deoxy-D-glucose.

Authors:  B I Hirschowitz; G Sachs
Journal:  Am J Physiol       Date:  1965-09

3.  Capsaicin effects on stress pathology and gastric acid secretion in rats.

Authors:  A M Dugani; G B Glavin
Journal:  Life Sci       Date:  1986-10-27       Impact factor: 5.037

4.  Distribution and characterization of calcitonin gene-related peptide immunoreactivity in the digestive system of normal and capsaicin-treated rats.

Authors:  C Sternini; J R Reeve; N Brecha
Journal:  Gastroenterology       Date:  1987-10       Impact factor: 22.682

Review 5.  The sensory-efferent function of capsaicin-sensitive sensory neurons.

Authors:  C A Maggi; A Meli
Journal:  Gen Pharmacol       Date:  1988

6.  The location of the chemoreceptor controlling gastric acid secretion during hypoglycaemia.

Authors:  D G Colin-Jones; R L Himsworth
Journal:  J Physiol       Date:  1970-02       Impact factor: 5.182

7.  Capsaicin-induced neuronal degeneration: silver impregnation of cell bodies, axons, and terminals in the central nervous system of the adult rat.

Authors:  S Ritter; T T Dinh
Journal:  J Comp Neurol       Date:  1988-05-01       Impact factor: 3.215

8.  Capsaicin pretreatment reduces the gastric acid secretion elicited by histamine but does not affect the responses to carbachol and pentagastrin.

Authors:  P Alföldi; F Obál; E Tóth; J Hideg
Journal:  Eur J Pharmacol       Date:  1986-04-29       Impact factor: 4.432
  8 in total
  8 in total

1.  Influence of capsaicin-sensitive afferent neurones on the acid secretory responses of the rat stomach in vivo.

Authors:  J V Esplugues; E G Ramos; L Gil; J Esplugues
Journal:  Br J Pharmacol       Date:  1990-07       Impact factor: 8.739

2.  Distribution of the vanilloid (capsaicin) receptor type 1 in the human stomach.

Authors:  Maria-Simonetta Faussone-Pellegrini; Antonio Taddei; Elisa Bizzoco; Massimo Lazzeri; Maria Giuliana Vannucchi; Paolo Bechi
Journal:  Histochem Cell Biol       Date:  2005-07-22       Impact factor: 4.304

3.  A critical re-evaluation of the specificity of action of perivagal capsaicin.

Authors:  K N Browning; T Babic; G M Holmes; E Swartz; R A Travagli
Journal:  J Physiol       Date:  2013-01-07       Impact factor: 5.182

4.  Differential effects of locally-applied capsaicin on distension-stimulated gastric acid secretion in the anesthetized rat.

Authors:  M D Barrachina; M A Martinez-Cuesta; A Canet; J V Esplugues; J Esplugues
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1992-12       Impact factor: 3.000

Review 5.  Vagal neurocircuitry and its influence on gastric motility.

Authors:  R Alberto Travagli; Laura Anselmi
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2016-05-25       Impact factor: 46.802

6.  Modulation by peripheral opioids of basal and distension-stimulated gastric acid secretion in the rat.

Authors:  J V Esplugues; M D Barrachina; J Esplugues
Journal:  Br J Pharmacol       Date:  1992-05       Impact factor: 8.739

Review 7.  Interdisciplinary review for correlation between the plant origin capsaicinoids, non-steroidal antiinflammatory drugs, gastrointestinal mucosal damage and prevention in animals and human beings.

Authors:  Gyula Mózsik; Tibor Past; Omar M E Abdel Salam; Mónika Kuzma; Pál Perjési
Journal:  Inflammopharmacology       Date:  2009-06-26       Impact factor: 4.473

8.  Peripheral N-methyl-D-aspartate receptor localization and role in gastric acid secretion regulation: immunofluorescence and pharmacological studies.

Authors:  Iuliia Golovynska; Tatiana V Beregova; Tatiana M Falalyeyeva; Ludmila I Stepanova; Sergii Golovynskyi; Junle Qu; Tymish Y Ohulchanskyy
Journal:  Sci Rep       Date:  2018-05-10       Impact factor: 4.379
  8 in total

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