Literature DB >> 28042916

Glucose homeostasis abnormalities among Cameroon patients with newly diagnosed hypertension.

Félicité Kamdem1,2, Daniel Lemogoum2, Marie-Solange Doualla1,3, Fernando Kemta Lepka1,4, Elvis Temfack1, Yvette Ngo Nouga1, Caroline Kenmegne1, Henry Luma1,3, Michel P Hermans5.   

Abstract

The authors assessed the frequency of glucose homeostasis abnormalities among 839 Cameroonians with newly diagnosed hypertension (mean age: 50.8±11 years; 49.9% female) in a cross-sectional survey conducted at the Douala General Hospital, Douala, Cameroon. In all participants, blood pressure, fasting plasma glucose (FPG), and lipids were recorded. Impaired fasting glycemia was described as an FPG level between 100 and 125 mg/dL and provisional diabetes as an FPG level ≥126 mg/dL. The FPG was 101±30 mg/dL. The overall proportion of abnormal glucose homeostasis was 38.3%, while 7.7% of patients (n=65) had known diabetes. A total of 23.7% (n=199) had impaired fasting glycemia and 6.8% (n=57) had provisional diabetes. Multivariable logistic regression revealed that male sex (odds ratio [OR], 1.53; 95% confidence interval [CI], 1.15-2.06), age older than 55 years (OR, 1.55; 95% CI, 1.15-2.09), and low-density lipoprotein cholesterol >1 g/L (OR, 1.34; 95% CI, 1.00-1.82) were independently associated with abnormal glucose homeostasis (all P<.05). Glucose homeostasis abnormalities are highly prevalent among Cameroonian patients with newly diagnosed hypertension. ©2016 Wiley Periodicals, Inc.

Entities:  

Keywords:  Cameroon; cardiovascular risk factors; diabetes; glucose homeostasis abnormalities; hypertension; impaired fasting glycemia; provisional diabetes

Mesh:

Substances:

Year:  2017        PMID: 28042916      PMCID: PMC8031355          DOI: 10.1111/jch.12959

Source DB:  PubMed          Journal:  J Clin Hypertens (Greenwich)        ISSN: 1524-6175            Impact factor:   3.738


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