| Literature DB >> 28034885 |
Alessandro Soria1, Claudia Alteri2, Gabriella Scarlatti3, Ada Bertoli2, Monica Tolazzi3, Emanuela Balestra2, Maria Concetta Bellocchi2, Fabio Continenza4, Luca Carioti2, Mara Biasin5, Daria Trabattoni5, Alessandra Bandera1, Francesca Ceccherini-Silberstein2, Carlo Federico Perno2, Andrea Gori1.
Abstract
A laboratory worker was infected with human immunodeficiency virus (HIV) type 1 in a biosafety level 2 containment facility, without any apparent breach. Through full-genome sequencing and phylogenetic analyses, we could identify the source of infection in a replication-competent clone that unknowingly contaminated a safe experiment. Mode of transmission remains unclear. Caution is warranted when handling HIV-derived constructs.Entities:
Keywords: HIV transmission.; HIV-1; laboratory safety; occupational exposure
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Year: 2017 PMID： 28034885 DOI： 10.1093/cid/ciw851
Source DB: PubMed Journal: Clin Infect Dis ISSN： 1058-4838 Impact factor: 9.079