Literature DB >> 28034498

Genomic sequencing and precision medicine in head and neck cancers.

R C Hoesli1, M L Ludwig1, N L Michmerhuizen1, A J Rosko1, M E Spector2, J C Brenner2, A C Birkeland3.   

Abstract

Head and neck squamous cell carcinoma (HNSCC) remains a common and deadly disease. Historically, surgical and chemoradiation treatments have been met with modest success, and understanding of genetic drivers of HNSCC has been limited. With recent next generation sequencing studies focused on HNSCC, we are beginning to understand the genetic landscape of HNSCCs and are starting to identify and advance targeted options for patients. In this review, we describe current knowledge and recent advances in sequencing studies of HNSCC, discuss current limitations and future directions for further genomic analysis, and highlight the translational advances being undertaken to treat this important disease.
Copyright © 2016 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

Entities:  

Keywords:  Genomics; HNSCC; Head and neck cancer; Personalized medicine; Precision medicine

Mesh：

Substances：

Year:  2016        PMID： 28034498      PMCID： PMC5393934          DOI： 10.1016/j.ejso.2016.12.002

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN： 0748-7983            Impact factor:   4.424


  77 in total

Review 1.  Cell-cycle checkpoints and cancer.

Authors:  Michael B Kastan; Jiri Bartek
Journal:  Nature       Date:  2004-11-18       Impact factor: 49.962

Review 2.  From signatures to models: understanding cancer using microarrays.

Authors:  Eran Segal; Nir Friedman; Naftali Kaminski; Aviv Regev; Daphne Koller
Journal:  Nat Genet       Date:  2005-06       Impact factor: 38.330

3.  Synonymous mutations frequently act as driver mutations in human cancers.

Authors:  Fran Supek; Belén Miñana; Juan Valcárcel; Toni Gabaldón; Ben Lehner
Journal:  Cell       Date:  2014-03-13       Impact factor: 41.582

4.  Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors.

Authors:  K Okami; L Wu; G Riggins; P Cairns; M Goggins; E Evron; N Halachmi; S A Ahrendt; A L Reed; W Hilgers; S E Kern; W M Koch; D Sidransky; J Jen
Journal:  Cancer Res       Date:  1998-02-01       Impact factor: 12.701

5.  Integrated genomic characterization of papillary thyroid carcinoma.

Authors: 
Journal:  Cell       Date:  2014-10-23       Impact factor: 41.582

Review 6.  The functional relevance of somatic synonymous mutations in melanoma and other cancers.

Authors:  Valer Gotea; Jared J Gartner; Nouar Qutob; Laura Elnitski; Yardena Samuels
Journal:  Pigment Cell Melanoma Res       Date:  2015-11       Impact factor: 4.693

7.  Squamous cell carcinoma of the oral tongue in young non-smokers is genomically similar to tumors in older smokers.

Authors:  Curtis R Pickering; Jiexin Zhang; David M Neskey; Mei Zhao; Samar A Jasser; Jiping Wang; Alexandra Ward; C Jillian Tsai; Marcus V Ortega Alves; Jane H Zhou; Jennifer Drummond; Adel K El-Naggar; Richard Gibbs; John N Weinstein; David A Wheeler; Jing Wang; Mitchell J Frederick; Jeffrey N Myers
Journal:  Clin Cancer Res       Date:  2014-05-29       Impact factor: 12.531

Review 8.  Human papillomavirus in HNSCC: recognition of a distinct disease type.

Authors:  Laura Vidal; Maura L Gillison
Journal:  Hematol Oncol Clin North Am       Date:  2008-12       Impact factor: 3.722

9.  Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012.

Authors:  Jacques Ferlay; Isabelle Soerjomataram; Rajesh Dikshit; Sultan Eser; Colin Mathers; Marise Rebelo; Donald Maxwell Parkin; David Forman; Freddie Bray
Journal:  Int J Cancer       Date:  2014-10-09       Impact factor: 7.396

10.  Oral cavity and pharynx cancer incidence trends by subsite in the United States: changing gender patterns.

Authors:  Linda Morris Brown; David P Check; Susan S Devesa
Journal:  J Oncol       Date:  2012-04-17       Impact factor: 4.375
View more
  4 in total

1.  Whole-Exome Sequencing of Sinonasal Small Cell Carcinoma Arising within a Papillary Schneiderian Carcinoma In Situ.

Authors:  Joshua Smith; Aditi Kulkarni; Andrew C Birkeland; Jonathan B McHugh; J Chad Brenner
Journal:  Otolaryngol Head Neck Surg       Date:  2018-05-08       Impact factor: 3.497

Review 2.  Crosstalk Between PD-1/PD-L1 Blockade and Its Combinatorial Therapies in Tumor Immune Microenvironment: A Focus on HNSCC.

Authors:  Weimin Lin; Miao Chen; Le Hong; Hang Zhao; Qianming Chen
Journal:  Front Oncol       Date:  2018-11-21       Impact factor: 6.244

3.  Whole exome sequencing identifies mTOR and KEAP1 as potential targets for radiosensitization of HNSCC cells refractory to EGFR and β1 integrin inhibition.

Authors:  Erik Klapproth; Ellen Dickreuter; Falk Zakrzewski; Michael Seifert; Andreas Petzold; Andreas Dahl; Evelin Schröck; Barbara Klink; Nils Cordes
Journal:  Oncotarget       Date:  2018-04-06

4.  The Prognostic and Therapeutic Value of the Mutational Profile of Blood and Tumor Tissue in Head and Neck Squamous Cell Carcinoma.

Authors:  Harper L Wilson; Ralph B D'Agostino; Nuwan Meegalla; Robin Petro; Sara Commander; Umit Topaloglu; Wei Zhang; Mercedes Porosnicu
Journal:  Oncologist       Date:  2020-11-20       Impact factor: 5.837
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.