Literature DB >> 28033102

Ectoine as a promising protective agent in humans and animals.

Adam Bownik, Zofia Stępniewska.   

Abstract

Ectoine is a compatible water molecule-binding solute (osmoprotectant) produced by several bacterial species in response to osmotic stress and unfavourable environmental conditions. This amino acid derivative can accumulate inside cells at high concentrations without interfering with natural processes and can protect the cell against radiation or osmotic stress. This brief review presents the current state of knowledge about the effects of ectoine on animals and focuses on its practical use for enzyme stabilisation, human skin protection, anti-inflammatory treatment, inhibitory effects in neurodegenerative diseases, and other therapeutic potential in human or veterinary medicine.

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Year:  2016        PMID: 28033102     DOI: 10.1515/aiht-2016-67-2837

Source DB:  PubMed          Journal:  Arh Hig Rada Toksikol        ISSN: 0004-1254            Impact factor:   1.948


  17 in total

1.  Bio-inspired solute enables preservation of human oocytes using minimum volume vitrification.

Authors:  Jung Kyu Choi; Rami El Assal; Nicholas Ng; Elizabeth Ginsburg; Richard L Maas; Raymond M Anchan; Utkan Demirci
Journal:  J Tissue Eng Regen Med       Date:  2017-08-25       Impact factor: 3.963

Review 2.  Role of the Extremolytes Ectoine and Hydroxyectoine as Stress Protectants and Nutrients: Genetics, Phylogenomics, Biochemistry, and Structural Analysis.

Authors:  Laura Czech; Lucas Hermann; Nadine Stöveken; Alexandra A Richter; Astrid Höppner; Sander H J Smits; Johann Heider; Erhard Bremer
Journal:  Genes (Basel)       Date:  2018-03-22       Impact factor: 4.096

3.  Dissecting Light Sensing and Metabolic Pathways on the Millimeter Scale in High-Altitude Modern Stromatolites.

Authors:  Daniel Gonzalo Alonso-Reyes; Fátima Silvina Galván; José Matías Irazoqui; Ariel Amadio; Diogo Tschoeke; Fabiano Thompson; Virginia Helena Albarracín; María Eugenia Farias
Journal:  Microb Ecol       Date:  2022-09-26       Impact factor: 4.192

4.  The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine.

Authors:  Alexandra A Richter; Stefanie Kobus; Laura Czech; Astrid Hoeppner; Jan Zarzycki; Tobias J Erb; Lukas Lauterbach; Jeroen S Dickschat; Erhard Bremer; Sander H J Smits
Journal:  J Biol Chem       Date:  2020-01-22       Impact factor: 5.157

5.  Rational flux-tuning of Halomonas bluephagenesis for co-production of bioplastic PHB and ectoine.

Authors:  Hong Ma; Yiqing Zhao; Wuzhe Huang; Lizhan Zhang; Fuqing Wu; Jianwen Ye; Guo-Qiang Chen
Journal:  Nat Commun       Date:  2020-07-03       Impact factor: 14.919

Review 6.  The biotechnological potential of marine bacteria in the novel lineage of Pseudomonas pertucinogena.

Authors:  Alexander Bollinger; Stephan Thies; Nadine Katzke; Karl-Erich Jaeger
Journal:  Microb Biotechnol       Date:  2018-06-25       Impact factor: 5.813

Review 7.  The Effectiveness of the Bacteria Derived Extremolyte Ectoine for the Treatment of Allergic Rhinitis.

Authors:  Andreas Bilstein; Nina Werkhäuser; Anna Rybachuk; Ralph Mösges
Journal:  Biomed Res Int       Date:  2021-06-01       Impact factor: 3.411

Review 8.  Emollient treatment of atopic dermatitis: latest evidence and clinical considerations.

Authors:  Kam Lun Hon; Jeng Sum Charmaine Kung; Wing Gi Gigi Ng; Ting Fan Leung
Journal:  Drugs Context       Date:  2018-04-17

Review 9.  Marine-Derived Compounds with Potential Use as Cosmeceuticals and Nutricosmetics.

Authors:  Ana Alves; Emília Sousa; Anake Kijjoa; Madalena Pinto
Journal:  Molecules       Date:  2020-05-29       Impact factor: 4.411

10.  Complexes of Ectoine with the Anionic Surfactants as Active Ingredients of Cleansing Cosmetics with Reduced Irritating Potential.

Authors:  Tomasz Bujak; Martyna Zagórska-Dziok; Zofia Nizioł-Łukaszewska
Journal:  Molecules       Date:  2020-03-21       Impact factor: 4.411

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