Literature DB >> 28031203

PER-8, a Novel Extended-Spectrum β-Lactamase PER Variant, from an Acinetobacter baumannii Clinical Isolate in Nepal.

Tatsuya Tada1, Shovita Shrestha2, Kayo Shimada1, Hiroshi Ohara3, Jeevan B Sherchand2, Bharat M Pokhrel4, Teruo Kirikae5.   

Abstract

A novel PER-type extended-spectrum β-lactamase, PER-8, was identified in an Acinetobacter baumannii clinical isolate obtained in Nepal. The amino acid sequence of PER-8 has a substitution at position 39 (Gly to Glu) compared with that of PER-7. The kcat/Km ratio of PER-8 for aztreonam was lower than that of PER-7, while the kcat/Km ratio of PER-8 for imipenem was higher than that of PER-7. The genomic environment surrounding blaPER-8 was intI1 blaPSE-1qacEDI sulI ISCR1-blaPER-8gts sulI orfX on a 100-kb plasmid.
Copyright © 2017 American Society for Microbiology.

Entities:  

Keywords:  Acinetobacter baumannii; PER-type ESBLs; plasmid-mediated resistance

Mesh：

Substances：

Year:  2017        PMID： 28031203      PMCID： PMC5328513          DOI： 10.1128/AAC.02300-16

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  26 in total

1.  PER-6, an extended-spectrum beta-lactamase from Aeromonas allosaccharophila.

Authors:  Delphine Girlich; Laurent Poirel; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2010-02-09       Impact factor: 5.191

2.  NDM-12, a novel New Delhi metallo-β-lactamase variant from a carbapenem-resistant Escherichia coli clinical isolate in Nepal.

Authors:  Tatsuya Tada; Basudha Shrestha; Tohru Miyoshi-Akiyama; Kayo Shimada; Hiroshi Ohara; Teruo Kirikae; Bharat M Pokhrel
Journal:  Antimicrob Agents Chemother       Date:  2014-08-04       Impact factor: 5.191

Review 3.  Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii: Mechanisms and epidemiology.

Authors:  Anaïs Potron; Laurent Poirel; Patrice Nordmann
Journal:  Int J Antimicrob Agents       Date:  2015-03-24       Impact factor: 5.283

4.  Evolution of multiresistance in nontyphoid salmonella serovars from 1984 to 1998 in Argentina.

Authors:  Betina E Orman; Silvia A Piñeiro; Sonia Arduino; Marcelo Galas; Roberto Melano; Maria I Caffer; Daniel O Sordelli; Daniela Centrón
Journal:  Antimicrob Agents Chemother       Date:  2002-12       Impact factor: 5.191

5.  Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum beta-lactamase.

Authors:  Andrea Endimiani; Francesco Luzzaro; Roberta Migliavacca; Elisabetta Mantengoli; Andrea M Hujer; Kristine M Hujer; Laura Pagani; Robert A Bonomo; Gian Maria Rossolini; Antonio Toniolo
Journal:  Antimicrob Agents Chemother       Date:  2007-04-02       Impact factor: 5.191

6.  Characterization and PCR-based replicon typing of resistance plasmids in Acinetobacter baumannii.

Authors:  Alessia Bertini; Laurent Poirel; Pauline D Mugnier; Laura Villa; Patrice Nordmann; Alessandra Carattoli
Journal:  Antimicrob Agents Chemother       Date:  2010-07-26       Impact factor: 5.191

7.  Extended-spectrum beta-lactamases in enterobacteriaceae in Buenos Aires, Argentina, public hospitals.

Authors:  M Quinteros; M Radice; N Gardella; M M Rodriguez; N Costa; D Korbenfeld; E Couto; G Gutkind
Journal:  Antimicrob Agents Chemother       Date:  2003-09       Impact factor: 5.191

8.  Nosocomial transmission of CTX-M-2 beta-lactamase-producing Acinetobacter baumannii in a neurosurgery ward.

Authors:  Noriyuki Nagano; Yukiko Nagano; Christophe Cordevant; Naohiro Shibata; Yoshichika Arakawa
Journal:  J Clin Microbiol       Date:  2004-09       Impact factor: 5.948

9.  Characterization of a novel extended-spectrum beta-lactamase from Pseudomonas aeruginosa.

Authors:  P Nordmann; E Ronco; T Naas; C Duport; Y Michel-Briand; R Labia
Journal:  Antimicrob Agents Chemother       Date:  1993-05       Impact factor: 5.191

10.  Outbreak of extended-spectrum beta-lactamase VEB-1-producing isolates of Acinetobacter baumannii in a French hospital.

Authors:  Laurent Poirel; Olivier Menuteau; Nathalie Agoli; Christian Cattoen; Patrice Nordmann
Journal:  J Clin Microbiol       Date:  2003-08       Impact factor: 5.948
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  1 in total

1.  Transposition of Tn1213 Encoding the PER-1 Extended-Spectrum β-Lactamase.

Authors:  Stefano Mancini; Laurent Poirel; Nicolas Kieffer; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2018-02-23       Impact factor: 5.191
  1 in total

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