| Literature DB >> 28031195 |
Costas C Papagiannitsis1, Leonidas S Tzouvelekis2, Eva Tzelepi1, Vivi Miriagou3.
Abstract
By searching the Integrall integron and GenBank databases, a novel open reading frame (ORF) of 51 nucleotides (nts) (ORF-17) overlapping the previously described ORF-11 was identified within the attI1 site in virtually all class 1 integrons. Using a set of isogenic plasmid constructs carrying a single gene cassette (blaGES-1) and possessing a canonical translation initiation region, we found that ORF-17 contributes to GES-1 expression.Entities:
Keywords: attI1 sequence; class 1 integrons; expression; gene cassettes
Mesh:
Substances:
Year: 2017 PMID: 28031195 PMCID: PMC5328530 DOI: 10.1128/AAC.02070-16
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191