Literature DB >> 2802563

In vitro activities of lomefloxacin and temafloxacin against pathogens causing diarrhea.

J Segreti1, J A Nelson, L J Goodman, R L Kaplan, G M Trenholme.   

Abstract

The in vitro activities of temafloxacin (A63004) and lomefloxacin (SC-47111; NY-198) were compared with those of seven other antibiotics against 146 isolates of bacterial enteric pathogens, including Campylobacter jejuni and Campylobacter coli. Ciprofloxacin was the most active drug against the Salmonella, Shigella, Yersinia, and Vibrio spp. tested. Lomefloxacin, temafloxacin, and difloxacin were the most active drugs tested against Campylobacter spp. (MIC for 90% of strains, 0.125 to 0.25 micrograms/ml).

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Year:  1989        PMID： 2802563      PMCID： PMC172661          DOI： 10.1128/AAC.33.8.1385

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  17 in total

1.  In vitro and in vivo activity of NY-198, a new difluorinated quinolone.

Authors:  T Hirose; E Okezaki; H Kato; Y Ito; M Inoue; S Mitsuhashi
Journal:  Antimicrob Agents Chemother       Date:  1987-06       Impact factor: 5.191

2.  Hippurate hydrolysis by Campylobacter fetus.

Authors:  S M Harvey
Journal:  J Clin Microbiol       Date:  1980-04       Impact factor: 5.948

3.  Clinical efficacy of ciprofloxacin compared with placebo in bacterial diarrhea.

Authors:  H E Pichler; G Diridl; K Stickler; D Wolf
Journal:  Am J Med       Date:  1987-04-27       Impact factor: 4.965

4.  In vitro susceptibility of Clostridium difficile to new beta-lactam and quinolone antibiotics.

Authors:  A W Chow; N Cheng; K H Bartlett
Journal:  Antimicrob Agents Chemother       Date:  1985-12       Impact factor: 5.191

5.  Ciprofloxacin or trimethoprim-sulfamethoxazole as initial therapy for travelers' diarrhea. A placebo-controlled, randomized trial.

Authors:  C D Ericsson; P C Johnson; H L Dupont; D R Morgan; J A Bitsura; F J de la Cabada
Journal:  Ann Intern Med       Date:  1987-02       Impact factor: 25.391

6.  Comparative in vitro activities of twelve antimicrobial agents against Campylobacter species.

Authors:  R M Fliegelman; R M Petrak; L J Goodman; J Segreti; G M Trenholme; R L Kaplan
Journal:  Antimicrob Agents Chemother       Date:  1985-03       Impact factor: 5.191

7.  Comparative in vitro activities of aztreonam, ciprofloxacin, norfloxacin, ofloxacin, HR 810 (a new cephalosporin), RU28965 (a new macrolide), and other agents against enteropathogens.

Authors:  H Goossens; P De Mol; H Coignau; J Levy; O Grados; G Ghysels; H Innocent; J P Butzler
Journal:  Antimicrob Agents Chemother       Date:  1985-03       Impact factor: 5.191

8.  In-vitro activity of lomefloxacin in comparison with pefloxacin and ofloxacin.

Authors:  P Van der Auwera; P Grenier; Y Glupczynski; D Pierard
Journal:  J Antimicrob Chemother       Date:  1989-02       Impact factor: 5.790

9.  Comparative antibacterial activities of temafloxacin hydrochloride (A-62254) and two reference fluoroquinolones.

Authors:  D J Hardy; R N Swanson; D M Hensey; N R Ramer; R R Bower; C W Hanson; D T Chu; P B Fernandes
Journal:  Antimicrob Agents Chemother       Date:  1987-11       Impact factor: 5.191

10.  Comparative in vitro activity of seven quinolones against 100 clinical isolates of Clostridium difficile.

Authors:  M Delmee; V Avesani
Journal:  Antimicrob Agents Chemother       Date:  1986-02       Impact factor: 5.191
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  8 in total

1.  Characterization of high-level quinolone resistance in Campylobacter jejuni.

Authors:  T D Gootz; B A Martin
Journal:  Antimicrob Agents Chemother       Date:  1991-05       Impact factor: 5.191

2.  Effect of lomefloxacin on the normal oral and intestinal microflora.

Authors:  C Edlund; B Brismar; C E Nord
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1990-01       Impact factor: 3.267

Review 3.  Lomefloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  A N Wadworth; K L Goa
Journal:  Drugs       Date:  1991-12       Impact factor: 9.546

4.  In vitro activities of cephalosporins and quinolones against Escherichia coli strains isolated from diarrheic dairy calves.

Authors:  J A Orden; J A Ruiz-Santa-Quiteria; S García; D Cid; R De La Fuente
Journal:  Antimicrob Agents Chemother       Date:  1999-03       Impact factor: 5.191

5.  In vitro activities of enoxacin, enrofloxacin, sparfloxacin, and ciprofloxacin against Escherichia coli strains isolated from diarrheic lambs and kids.

Authors:  D Cid; S Piriz; J A Ruiz-Santa-Quiteria; J Valle; S Garcia; S Vadillo; R de la Fuente
Journal:  Antimicrob Agents Chemother       Date:  1994-10       Impact factor: 5.191

6.  Reduced susceptibilities of Shigella sonnei strains isolated from patients with dysentery to fluoroquinolones.

Authors:  S Horiuchi; Y Inagaki; N Yamamoto; N Okamura; Y Imagawa; R Nakaya
Journal:  Antimicrob Agents Chemother       Date:  1993-11       Impact factor: 5.191

7.  In vitro activities of tosufloxacin, temafloxacin, and A-56620 against pathogens of diarrhea.

Authors:  J P Bryan; C Waters; J Sheffield; R E Krieg; P L Perine; K Wagner
Journal:  Antimicrob Agents Chemother       Date:  1990-02       Impact factor: 5.191

8.  Activities of newer fluoroquinolones against Shigella sonnei.

Authors:  J F John; L T Atkins; P A Maple; M Bratoeva
Journal:  Antimicrob Agents Chemother       Date:  1992-10       Impact factor: 5.191
  8 in total

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