Literature DB >> 28017836

Recent advances in hyaluronic acid-decorated nanocarriers for targeted cancer therapy.

Jennifer M Wickens1, Hashem O Alsaab2, Prashant Kesharwani3, Ketki Bhise2, Mohd Cairul Iqbal Mohd Amin4, Rakesh Kumar Tekade5, Umesh Gupta6, Arun K Iyer7.   

Abstract

The cluster-determinant 44 (CD44) receptor has a high affinity for hyaluronic acid (HA) binding and is a desirable receptor for active targeting based on its overexpression in cancer cells compared with normal body cells. The nanocarrier affinity can be increased by conjugating drug-loaded carriers with HA, allowing enhanced cancer cell uptake via the HA-CD44 receptor-mediated endocytosis pathway. In this review, we discuss recent advances in HA-based nanocarriers and micelles for cancer therapy. In vitro and in vivo experiments have repeatedly indicated HA-based nanocarriers to be a target-specific drug and gene delivery platform with great promise for future applications in clinical cancer therapy.
Copyright © 2016 Elsevier Ltd. All rights reserved.

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Year:  2016        PMID： 28017836      PMCID： PMC5413407          DOI： 10.1016/j.drudis.2016.12.009

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  93 in total

1.  Redox-sensitive micelles self-assembled from amphiphilic hyaluronic acid-deoxycholic acid conjugates for targeted intracellular delivery of paclitaxel.

Authors:  Jing Li; Meirong Huo; Jing Wang; Jianping Zhou; Jumah M Mohammad; Yinlong Zhang; Qinnv Zhu; Ayman Y Waddad; Qiang Zhang
Journal:  Biomaterials       Date:  2011-12-12       Impact factor: 12.479

2.  Enhanced permeability and retention effect for selective targeting of anticancer nanomedicine: are we there yet?

Authors: 
Journal:  Drug Discov Today Technol       Date:  2012

3.  Synthesis and optimization of a novel polymeric micelle based on hyaluronic acid and phospholipids for delivery of paclitaxel, in vitro and in-vivo evaluation.

Authors:  Ebrahim Saadat; Mohsen Amini; Mohammad Reza Khoshayand; Rassoul Dinarvand; Farid A Dorkoosh
Journal:  Int J Pharm       Date:  2014-08-20       Impact factor: 5.875

4.  Cluster of Differentiation 44 Targeted Hyaluronic Acid Based Nanoparticles for MDR1 siRNA Delivery to Overcome Drug Resistance in Ovarian Cancer.

Authors:  Xiaoqian Yang; Arun K Iyer; Amit Singh; Lara Milane; Edwin Choy; Francis J Hornicek; Mansoor M Amiji; Zhenfeng Duan
Journal:  Pharm Res       Date:  2014-12-17       Impact factor: 4.200

5.  Preparation of HIFU-triggered tumor-targeted hyaluronic acid micelles for controlled drug release and enhanced cellular uptake.

Authors:  Shaohui Zheng; Zhen Jin; Jiwon Han; Sunghoon Cho; Van Du Nguyen; Seong Young Ko; Jong-Oh Park; Sukho Park
Journal:  Colloids Surf B Biointerfaces       Date:  2016-03-09       Impact factor: 5.268

6.  High intensity focused ultrasound responsive metallo-supramolecular block copolymer micelles.

Authors:  Bo Liang; Rui Tong; Zhenhua Wang; Shengwei Guo; Hesheng Xia
Journal:  Langmuir       Date:  2014-07-29       Impact factor: 3.882

7.  A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Authors:  Y Matsumura; H Maeda
Journal:  Cancer Res       Date:  1986-12       Impact factor: 12.701

8.  MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer.

Authors:  Xiaoqian Yang; Arun K Iyer; Amit Singh; Edwin Choy; Francis J Hornicek; Mansoor M Amiji; Zhenfeng Duan
Journal:  Sci Rep       Date:  2015-02-17       Impact factor: 4.379

9.  Phototheranostics of CD44-positive cell populations in triple negative breast cancer.

Authors:  Jiefu Jin; Balaji Krishnamachary; Yelena Mironchik; Hisataka Kobayashi; Zaver M Bhujwalla
Journal:  Sci Rep       Date:  2016-06-15       Impact factor: 4.379

10.  CD44 variant 9 expression in primary early gastric cancer as a predictive marker for recurrence.

Authors:  K Hirata; H Suzuki; H Imaeda; J Matsuzaki; H Tsugawa; O Nagano; K Asakura; H Saya; T Hibi
Journal:  Br J Cancer       Date:  2013-06-18       Impact factor: 7.640
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  35 in total

Review 1.  Bioinspired Shielding Strategies for Nanoparticle Drug Delivery Applications.

Authors:  Neetu M Gulati; Phoebe L Stewart; Nicole F Steinmetz
Journal:  Mol Pharm       Date:  2018-05-15       Impact factor: 4.939

2.  Hyaluronic acid derivative-modified nano-structured lipid carrier for cancer targeting and therapy.

Authors:  Xiao Liu; Hai Liu; Su-Lan Wang; Jing-Wen Liu
Journal:  J Zhejiang Univ Sci B       Date:  2020-07       Impact factor: 3.066

3.  CD44 directed nanomicellar payload delivery platform for selective anticancer effect and tumor specific imaging of triple negative breast cancer.

Authors:  Zhaoxian Wang; Samaresh Sau; Hashem O Alsaab; Arun K Iyer
Journal:  Nanomedicine       Date:  2018-04-17       Impact factor: 5.307

4.  Folic acid conjugated polymeric micelles loaded with a curcumin difluorinated analog for targeting cervical and ovarian cancers.

Authors:  Duy Luong; Prashant Kesharwani; Hashem O Alsaab; Samaresh Sau; Subhash Padhye; Fazlul H Sarkar; Arun K Iyer
Journal:  Colloids Surf B Biointerfaces       Date:  2017-06-21       Impact factor: 5.268

5.  Tumor hypoxia directed multimodal nanotherapy for overcoming drug resistance in renal cell carcinoma and reprogramming macrophages.

Authors:  Hashem O Alsaab; Samaresh Sau; Rami M Alzhrani; Vino T Cheriyan; Lisa A Polin; Ulka Vaishampayan; Arun K Rishi; Arun K Iyer
Journal:  Biomaterials       Date:  2018-08-30       Impact factor: 12.479

Review 6.  A tumor multicomponent targeting chemoimmune drug delivery system for reprograming the tumor microenvironment and personalized cancer therapy.

Authors:  Samaresh Sau; Katyayani Tatiparti; Hashem O Alsaab; Sushil K Kashaw; Arun K Iyer
Journal:  Drug Discov Today       Date:  2018-03-15       Impact factor: 7.851

7.  Upconversion in photodynamic therapy: plumbing the depths.

Authors:  Michael R Hamblin
Journal:  Dalton Trans       Date:  2018-02-16       Impact factor: 4.390

Review 8.  Improving the therapeutic efficiency of noncoding RNAs in cancers using targeted drug delivery systems.

Authors:  Rami Alzhrani; Hashem O Alsaab; Alex Petrovici; Ketki Bhise; Kushal Vanamala; Samaresh Sau; Matthew J Krinock; Arun K Iyer
Journal:  Drug Discov Today       Date:  2019-11-20       Impact factor: 7.851

9.  Enhancing Radiotherapeutic Effect With Nanoparticle-Mediated Radiosensitizer Delivery Guided By Focused Gamma Rays In Lewis Lung Carcinoma-Bearing Mouse Brain Tumor Models.

Authors:  Sa-Hoe Lim; Chun-Hao Li; Young-Il Jeong; Woo-Youl Jang; Jin-Myung Choi; Shin Jung
Journal:  Int J Nanomedicine       Date:  2019-11-13

10.  Comparison Direct Synthesis of Hyaluronic Acid-Based Carbon Nanodots as Dual Active Targeting and Imaging of HeLa Cancer Cells.

Authors:  Yu-Yu Aung; Aswandi Wibrianto; Jefry S Sianturi; Desita K Ulfa; Satya C W Sakti; Irzaman Irzaman; Brian Yuliarto; Jia-Yaw Chang; Yaung Kwee; Mochamad Z Fahmi
Journal:  ACS Omega       Date:  2021-05-11
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