Literature DB >> 28013038

Potential Implications of Shortening Length of Stay Following Radical Cystectomy in a Pre-ERAS Population.

Takahiro Osawa1, Sapan N Ambani1, Kola Olugbade1, Ted A Skolarus1, Alon Z Weizer1, Jeffrey S Montgomery1, Chang He1, Khaled S Hafez1, Brent K Hollenbeck1, Cheryl T Lee1, James E Montie1, Ganesh S Palapattu1, Todd M Morgan2.   

Abstract

OBJECTIVE: To investigate whether shortened inpatient length of stay (LOS) after radical cystectomy (RC) is associated with increased complication rates after hospital discharge.
MATERIALS AND METHODS: The analytic cohort comprised 484 consecutive patients with 90-day follow-up who underwent RC at our institution from 2005 to 2012 and with LOS ≤9 days. Patients were categorized according to LOS as short (s-LOS; ≤5 days) or routine (r-LOS; 6-9 days). The primary outcome was major complications (Clavien-Dindo grades 3-5) occurring within 90 days after discharge. A Cox proportional hazards model was used to determine the association between LOS and post-discharge major complications. Hospital readmission was a secondary outcome.
RESULTS: Patients in the s-LOS cohort had fewer comorbidities (P < .01), less frequently received neoadjuvant chemotherapy (P = .02), and more often underwent robotic RC (P < .01). Major outpatient complications occurred in 18.1% of s-LOS patients vs 11.2% of r-LOS patients, and s-LOS was associated with a significant independent increase in the risk of major outpatient complications (hazard ratio 1.91, 95% confidence interval 1.03-3.56, P = .04). There was also a statistically significant association between s-LOS and readmission (hazard ratio 1.60, 95% confidence interval 1.01-2.44, P = .048).
CONCLUSION: Early discharge post RC appears to be associated with an increased risk of major outpatient complications, suggesting that attempts to reduce LOS may need to be supplemented by additional outpatient services to diminish this effect. Further attention should be given to understanding how to better support patients discharged after a short LOS.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Year:  2016        PMID: 28013038     DOI: 10.1016/j.urology.2016.10.051

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  5 in total

Review 1.  An Update in Enhanced Recovery Following Radical Cystectomy.

Authors:  Saum Ghodoussipour; Hooman Djaladat
Journal:  Curr Urol Rep       Date:  2018-10-18       Impact factor: 3.092

Review 2.  Role of prehabilitation following major uro-oncologic surgery: a narrative review.

Authors:  Enrico Maria Minnella; Francesco Carli; Wassim Kassouf
Journal:  World J Urol       Date:  2020-10-31       Impact factor: 3.661

3.  The impact of patient-related nonmodifiable factors on perioperative outcomes following radical cystectomy with enhanced recovery protocol.

Authors:  Daniel Zainfeld; Jian Chen; Jie Cai; Gus Miranda; Anne Schuckman; Siamak Daneshmand; Hooman Djaladat
Journal:  Ther Adv Urol       Date:  2018-11-14

4.  Selecting candidates for early discharge after radical cystectomy for bladder cancer.

Authors:  Valérie Fonteyne; Elke Rammant; Karel Decaestecker
Journal:  Transl Androl Urol       Date:  2018-03

5.  Enhanced recovery after surgery (ERAS) protocols in patients undergoing radical cystectomy with ileal urinary diversions: A randomized controlled trial.

Authors:  Olaru Vlad; Baston Catalin; Harza Mihai; Preda Adrian; Olaru Manuela; Ismail Gener; Sinescu Ioanel
Journal:  Medicine (Baltimore)       Date:  2020-07-02       Impact factor: 1.817

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.