Dongxin Lin1, Qianting Ou1, Jialing Lin1, Yang Peng2, Zhenjiang Yao3. 1. Department of Epidemiology and Health Statistics, Guangdong Pharmaceutical University, Guangzhou, China. 2. Centre for Chronic Diseases, University of Queensland, Brisbane, QLD, Australia. 3. Department of Epidemiology and Health Statistics, Guangdong Pharmaceutical University, Guangzhou, China. Electronic address: zhjyao2001@yahoo.com.
Abstract
BACKGROUND: Health care workers may potentially spread Staphylococcus aureus and methicillin-resistant S aureus (MRSA) to patients by contaminated high-touch items. We aimed to determine the pooled rates of S aureus and MRSA contamination and influencing factors. METHODS: A literature search of the PubMed, ScienceDirect, Embase, Ovid, and Scopus databases was performed. Pooled contamination rates were determined using random effect models. Subgroup and meta-regression analyses were conducted to identify factors potentially influencing the rates of S aureus and MRSA contamination. Sensitivity and publication bias analyses were performed. RESULTS: Thirty-eight studies were included in the meta-analysis. The pooled contamination rates were 15.0% (95% confidence interval [CI], 9.8%-21.1%) for S aureus and 5.0% (95% CI, 2.7%-7.7%) for MRSA. The subgroup analyses indicated that the pooled rate of S aureus contamination was significantly higher for studies conducted in South America, in developing countries, and during 2010-2015. The pooled rate of MRSA contamination was significantly higher for studies conducted in Africa. The meta-regression analysis suggested that the pooled rate of S aureus contamination was lower for studies conducted in developed countries (odds ratio, 0.664; 95% CI, 0.509-0.867; P = .004). No bias was found in the publication of the rates of S aureus and MRSA contamination. CONCLUSIONS: S aureus and MRSA contamination statuses of high-touch items are worrisome and should be paid greater attention. Developing country status was a risk factor for S aureus contamination.
BACKGROUND: Health care workers may potentially spread Staphylococcus aureus and methicillin-resistant S aureus (MRSA) to patients by contaminated high-touch items. We aimed to determine the pooled rates of S aureus and MRSA contamination and influencing factors. METHODS: A literature search of the PubMed, ScienceDirect, Embase, Ovid, and Scopus databases was performed. Pooled contamination rates were determined using random effect models. Subgroup and meta-regression analyses were conducted to identify factors potentially influencing the rates of S aureus and MRSA contamination. Sensitivity and publication bias analyses were performed. RESULTS: Thirty-eight studies were included in the meta-analysis. The pooled contamination rates were 15.0% (95% confidence interval [CI], 9.8%-21.1%) for S aureus and 5.0% (95% CI, 2.7%-7.7%) for MRSA. The subgroup analyses indicated that the pooled rate of S aureus contamination was significantly higher for studies conducted in South America, in developing countries, and during 2010-2015. The pooled rate of MRSA contamination was significantly higher for studies conducted in Africa. The meta-regression analysis suggested that the pooled rate of S aureus contamination was lower for studies conducted in developed countries (odds ratio, 0.664; 95% CI, 0.509-0.867; P = .004). No bias was found in the publication of the rates of S aureus and MRSA contamination. CONCLUSIONS: S aureus and MRSA contamination statuses of high-touch items are worrisome and should be paid greater attention. Developing country status was a risk factor for S aureus contamination.
Authors: Agata Jabłońska-Trypuć; Marcin Makuła; Maria Włodarczyk-Makuła; Elżbieta Wołejko; Urszula Wydro; Lluis Serra-Majem; Józefa Wiater Journal: Int J Environ Res Public Health Date: 2022-07-01 Impact factor: 4.614
Authors: Aída Hamdan-Partida; Samuel González-García; Francisco Javier Martínez-Ruíz; Miguel Ángel Zavala-Sánchez; Anaíd Bustos-Hamdan; Jaime Bustos-Martínez Journal: Microorganisms Date: 2022-03-21