Inés Oliveira Souto1, Izaskun Alejo-Cancho2, Joaquim Gascón Brustenga1, Aida Peiró Mestres2, Jose Muñoz Gutiérrez1, Miguel J Martínez Yoldi3. 1. ISGlobal, Barcelona Centre for International Health Research (CRESIB), Tropical Medicine and International Health Department, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain. 2. Department of Clinical Microbiology, Hospital Clínic, c/ Villarroel 170, 08036 Barcelona, Spain. 3. ISGlobal, Barcelona Centre for International Health Research (CRESIB), Tropical Medicine and International Health Department, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain; Department of Clinical Microbiology, Hospital Clínic, c/ Villarroel 170, 08036 Barcelona, Spain. Electronic address: myoldi@clinic.ub.es.
Abstract
INTRODUCTION: Zika virus is mainly transmitted through the bites of infected Aedes mosquitoes, although mother-to-child and sexual transmission have also been described. The presence of Zika virus in semen after infection seems to be not uncommon, but the duration of viral persistence has not been well-determined. METHODS: Molecular, serological and cell culture methods were used for the diagnosis and follow up of a case of Zika virus infection imported from Venezuela. Serial samples of serum, urine and semen were analyzed to investigate the persistence of the Zika virus. RESULTS: Zika virus was detected in semen samples up to 93 days after the onset of symptoms. CONCLUSIONS: Our results confirm the persistence of Zika virus in semen samples for long periods after infection.
INTRODUCTION:Zika virus is mainly transmitted through the bites of infected Aedes mosquitoes, although mother-to-child and sexual transmission have also been described. The presence of Zika virus in semen after infection seems to be not uncommon, but the duration of viral persistence has not been well-determined. METHODS: Molecular, serological and cell culture methods were used for the diagnosis and follow up of a case of Zika virus infection imported from Venezuela. Serial samples of serum, urine and semen were analyzed to investigate the persistence of the Zika virus. RESULTS:Zika virus was detected in semen samples up to 93 days after the onset of symptoms. CONCLUSIONS: Our results confirm the persistence of Zika virus in semen samples for long periods after infection.
Authors: Tereza Magalhaes; Brian D Foy; Ernesto T A Marques; Gregory D Ebel; James Weger-Lucarelli Journal: Virus Res Date: 2017-07-11 Impact factor: 3.303
Authors: Anna B Kawiecki; E Handly Mayton; M Fausta Dutuze; Brad A Goupil; Ingeborg M Langohr; Fabio Del Piero; Rebecca C Christofferson Journal: Virol J Date: 2017-04-18 Impact factor: 4.099
Authors: Ana Carolina B Terzian; Cássia Fernanda Estofolete; Rafael Alves da Silva; Denise Cristina Mós Vaz-Oliani; Antonio Hélio Oliani; Cinara Cássia Brandão de Mattos; Luiz Carlos de Mattos; Paula Rahal; Maurício L Nogueira Journal: Emerg Infect Dis Date: 2017-11 Impact factor: 6.883
Authors: Raquel das Neves Almeida; Heloisa Antoniella Braz-de-Melo; Igor de Oliveira Santos; Rafael Corrêa; Gary P Kobinger; Kelly Grace Magalhaes Journal: Cells Date: 2020-04-18 Impact factor: 6.600
Authors: Emma L Mohr; Lindsey N Block; Christina M Newman; Laurel M Stewart; Michelle Koenig; Matthew Semler; Meghan E Breitbach; Leandro B C Teixeira; Xiankun Zeng; Andrea M Weiler; Gabrielle L Barry; Troy H Thoong; Gregory J Wiepz; Dawn M Dudley; Heather A Simmons; Andres Mejia; Terry K Morgan; M Shahriar Salamat; Sarah Kohn; Kathleen M Antony; Matthew T Aliota; Mariel S Mohns; Jennifer M Hayes; Nancy Schultz-Darken; Michele L Schotzko; Eric Peterson; Saverio Capuano; Jorge E Osorio; Shelby L O'Connor; Thomas C Friedrich; David H O'Connor; Thaddeus G Golos Journal: PLoS One Date: 2018-01-30 Impact factor: 3.240