Literature DB >> 28811170

Zika virus research models.

Jessica L Kublin1, James B Whitney2.   

Abstract

The 2015 Brazilian Zika virus outbreak sparked a rapid response to control the spread of the virus. What was first understood to be a mild self-resolving infection is now linked to significant neurological defects in both neonates and adults. The WHO declared the 2016 Zika epidemic a public health emergency and issued an unprecedented recommendation to women in affected regions to delay pregnancy until the risks surrounding Zika virus could be understood, or the epidemic contained. Since that time, considerable effort has been dedicated to understanding Zika transmission and pathogenesis to aid the development of drugs and vaccines. Several models have emerged to study numerous facets of Zika biology; this review details the various model systems.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cell culture models; Nonhuman primate models; Therapeutics; Vaccines; Zika virus

Mesh:

Substances:

Year:  2017        PMID: 28811170      PMCID: PMC5809325          DOI: 10.1016/j.virusres.2017.07.025

Source DB:  PubMed          Journal:  Virus Res        ISSN: 0168-1702            Impact factor:   3.303


  105 in total

1.  Zika virus. I. Isolations and serological specificity.

Authors:  G W A DICK; S F KITCHEN; A J HADDOW
Journal:  Trans R Soc Trop Med Hyg       Date:  1952-09       Impact factor: 2.184

2.  Zika Virus NS4A and NS4B Proteins Deregulate Akt-mTOR Signaling in Human Fetal Neural Stem Cells to Inhibit Neurogenesis and Induce Autophagy.

Authors:  Qiming Liang; Zhifei Luo; Jianxiong Zeng; Weiqiang Chen; Suan-Sin Foo; Shin-Ae Lee; Jianning Ge; Su Wang; Steven A Goldman; Berislav V Zlokovic; Zhen Zhao; Jae U Jung
Journal:  Cell Stem Cell       Date:  2016-08-11       Impact factor: 24.633

3.  Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys.

Authors:  Peter Abbink; Rafael A Larocca; Rafael A De La Barrera; Christine A Bricault; Edward T Moseley; Michael Boyd; Marinela Kirilova; Zhenfeng Li; David Ng'ang'a; Ovini Nanayakkara; Ramya Nityanandam; Noe B Mercado; Erica N Borducchi; Arshi Agarwal; Amanda L Brinkman; Crystal Cabral; Abishek Chandrashekar; Patricia B Giglio; David Jetton; Jessica Jimenez; Benjamin C Lee; Shanell Mojta; Katherine Molloy; Mayuri Shetty; George H Neubauer; Kathryn E Stephenson; Jean Pierre S Peron; Paolo M de A Zanotto; Johnathan Misamore; Brad Finneyfrock; Mark G Lewis; Galit Alter; Kayvon Modjarrad; Richard G Jarman; Kenneth H Eckels; Nelson L Michael; Stephen J Thomas; Dan H Barouch
Journal:  Science       Date:  2016-08-04       Impact factor: 47.728

4.  A sensitive virus yield assay for evaluation of Antivirals against Zika Virus.

Authors:  Scott Goebel; Beth Snyder; Timothy Sellati; Mohammad Saeed; Roger Ptak; Michael Murray; Robert Bostwick; Jonathan Rayner; Fusataka Koide; Raj Kalkeri
Journal:  J Virol Methods       Date:  2016-10-03       Impact factor: 2.014

5.  Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling.

Authors:  Alesha Grant; Sanket S Ponia; Shashank Tripathi; Vinod Balasubramaniam; Lisa Miorin; Marion Sourisseau; Megan C Schwarz; Mari Paz Sánchez-Seco; Matthew J Evans; Sonja M Best; Adolfo García-Sastre
Journal:  Cell Host Microbe       Date:  2016-05-19       Impact factor: 21.023

6.  Zika virus, French polynesia, South pacific, 2013.

Authors:  Van-Mai Cao-Lormeau; Claudine Roche; Anita Teissier; Emilie Robin; Anne-Laure Berry; Henri-Pierre Mallet; Amadou Alpha Sall; Didier Musso
Journal:  Emerg Infect Dis       Date:  2014-06       Impact factor: 6.883

7.  Vaccine protection against Zika virus from Brazil.

Authors:  Rafael A Larocca; Peter Abbink; Jean Pierre S Peron; Paolo M de A Zanotto; M Justin Iampietro; Alexander Badamchi-Zadeh; Michael Boyd; David Ng'ang'a; Marinela Kirilova; Ramya Nityanandam; Noe B Mercado; Zhenfeng Li; Edward T Moseley; Christine A Bricault; Erica N Borducchi; Patricia B Giglio; David Jetton; George Neubauer; Joseph P Nkolola; Lori F Maxfield; Rafael A De La Barrera; Richard G Jarman; Kenneth H Eckels; Nelson L Michael; Stephen J Thomas; Dan H Barouch
Journal:  Nature       Date:  2016-06-28       Impact factor: 49.962

Review 8.  Zika Virus and Sexual Transmission: A New Route of Transmission for Mosquito-borne Flaviviruses
.

Authors:  Andrew K Hastings; Erol Fikrig
Journal:  Yale J Biol Med       Date:  2017-06-23

9.  ZIKA virus reveals broad tissue and cell tropism during the first trimester of pregnancy.

Authors:  Hicham El Costa; Jordi Gouilly; Jean-Michel Mansuy; Qian Chen; Claude Levy; Géraldine Cartron; Francisco Veas; Reem Al-Daccak; Jacques Izopet; Nabila Jabrane-Ferrat
Journal:  Sci Rep       Date:  2016-10-19       Impact factor: 4.379

10.  Characterization of a Novel Murine Model to Study Zika Virus.

Authors:  Shannan L Rossi; Robert B Tesh; Sasha R Azar; Antonio E Muruato; Kathryn A Hanley; Albert J Auguste; Rose M Langsjoen; Slobodan Paessler; Nikos Vasilakis; Scott C Weaver
Journal:  Am J Trop Med Hyg       Date:  2016-03-28       Impact factor: 2.345

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  4 in total

1.  Inhibition of zika virus infection by fused tricyclic derivatives of 1,2,4,5-tetrahydroimidazo[1,5-a]quinolin-3(3aH)-one.

Authors:  Bin Xu; Emily M Lee; Angelica Medina; Xia Sun; Decai Wang; Hengli Tang; Guo-Chun Zhou
Journal:  Bioorg Chem       Date:  2020-09-01       Impact factor: 5.275

2.  A DNA Vaccine Protects Human Immune Cells against Zika Virus Infection in Humanized Mice.

Authors:  Guohua Yi; Xuequn Xu; Sojan Abraham; Sean Petersen; Hua Guo; Nora Ortega; Premlata Shankar; N Manjunath
Journal:  EBioMedicine       Date:  2017-10-06       Impact factor: 8.143

Review 3.  Zika virus infection and implications for kidney disease.

Authors:  Donald J Alcendor
Journal:  J Mol Med (Berl)       Date:  2018-08-31       Impact factor: 4.599

4.  Interferon Epsilon Signaling Confers Attenuated Zika Replication in Human Vaginal Epithelial Cells.

Authors:  James W Mungin; Xin Chen; Bindong Liu
Journal:  Pathogens       Date:  2022-07-29
  4 in total

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