Literature DB >> 28006086

Recurrent oral cavity cancer: Patterns of failure after salvage multimodality therapy.

Sean R Quinlan-Davidson1, William H Morrison1, Jeffrey N Myers2, Gary B Gunn1, William N William3, Beth M Beadle1, Heath D Skinner1, Ann M Gillenwater2, Steven J Frank1, Jack Phan1, Faye M Johnson3, Clifton D Fuller1, Mark E Zafereo2, David I Rosenthal1, Adam S Garden1.   

Abstract

BACKGROUND: We focused on a cohort of radiation naïve patients who had recurrent oral cavity cancer (recurrent OCC) to assess their outcomes with salvage multimodal therapy.
METHODS: A retrospective single institutional study was performed of patients with recurrent OCC. Disease recurrence and survival outcomes were assessed.
RESULTS: Seventy-eight patients were analyzed. All patients had salvage surgery and intensity-modulated radiotherapy (IMRT) and 74% had chemotherapy. Five-year overall survival, recurrence-free survival, and locoregional control rates were 59%, 60%, and 74%, respectively.
CONCLUSION: Outcomes of radiation naïve patients with recurrent OCC are fair, and seem similar with patients with locally advanced nonrecurrent OCC treated with multimodal therapy.
© 2016 Wiley Periodicals, Inc. Head Neck 39: 633-638, 2017. © 2016 Wiley Periodicals, Inc.

Entities:  

Keywords:  early stage; intensity-modulated radiotherapy (IMRT); oral cavity cancer; radiotherapy; salvage

Mesh:

Year:  2016        PMID: 28006086     DOI: 10.1002/hed.24666

Source DB:  PubMed          Journal:  Head Neck        ISSN: 1043-3074            Impact factor:   3.147


  4 in total

1.  Long-term outcomes in oral cavity squamous cell carcinoma with adjuvant and salvage radiotherapy after surgery.

Authors:  Evangelia Katsoulakis; Jonathan E Leeman; Benjamin H Lok; Weiji Shi; Zhigang Zhang; Jillian C Tsai; Sean M McBride; Eric J Sherman; Marc Cohen; Richard Wong; Ian Ganly; Nancy Y Lee; Nadeem Riaz
Journal:  Laryngoscope       Date:  2018-04-10       Impact factor: 3.325

2.  Evolution of oral neoplasm in an andalusian population (Spain).

Authors:  R Flores-Ruiz; L Castellanos-Cosano; M-A Serrera-Figallo; A Gutiérrez-Corrales; R Castillo-Oyague; J-L Gutiérrez-Perez; D Torres-Lagares
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2018-01-01

Review 3.  Salvage Surgery in Recurrent Oral Squamous Cell Carcinoma.

Authors:  K S Rathan Shetty; Vinayak Kurle; P Greeshma; Veena B Ganga; Samskruthi P Murthy; Siddappa K Thammaiah; P Krishna Prasad; Purushottham Chavan; Rajshekar Halkud; R Krishnappa
Journal:  Front Oral Health       Date:  2022-01-28

4.  Salvage surgery for patients with residual/persistent diseases after improper or insufficient treatment of oral squamous cell carcinoma: can we rectify these mistakes?

Authors:  Yue He; Zhonglong Liu; Surui Sheng; Weijin Gao; Xiao Tang; Xiaoguang Li; Chunyue Ma
Journal:  BMC Cancer       Date:  2021-07-31       Impact factor: 4.430

  4 in total

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