Marc Labetoulle1, Maurizio Rolando2, Christophe Baudouin3, Gysbert van Setten4. 1. Ophthalmology Department, Bicêtre Hospital, APHP, South Paris University, Le Kremlin-Bicêtre, France. 2. University of Genoa, Genoa, Italy. 3. Quinze-Vingts National Ophthalmology Hospital, Paris, France. 4. St Eriks Eye Hospital, Stockholm, Sweden.
Abstract
BACKGROUND/AIMS: To improve understanding of patients' experience and perception of dry eye disease (DED) and its impact on quality of life (QoL). METHODS: This survey was observational, non-interventional and cross-sectional. The survey was conducted online on 706 patients with DED from five European countries (France, Germany, Italy, Spain and the UK). All patients met the following inclusion criteria: 40 years or older with DED diagnosed by a healthcare professional (HCP), not wearing contact lenses and using tear substitutes daily for at least 6 months. The survey (performed in the five native languages) included 9 screening questions (inclusion criteria) and 26 complementary questions about patients' demography, disease history, DED diagnosis, use of relief treatments, perceptions of DED condition and its impact on QoL. RESULTS: Overall, 218 of 706 (31%) patients perceived DED as a 'disease' or even a 'handicap', and 468 of 706 (66%) as a 'discomfort'. High impact of DED on patients' QoL was associated with negative perception, delay in diagnosis, visits to more than one HCP before diagnosis and high frequency of treatment use. This survey also provided us with a list of language-specific keywords that patients used most frequently to spontaneously describe their condition. CONCLUSIONS: Findings showed that negative perception of DED, delayed diagnosis and high frequency of treatment use were inter-related, and that all have a negative impact on patients' QoL. The generated language-specific keywords used to describe DED could serve as the basis for a comprehensive QoL questionnaire to be used in clinical settings. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
BACKGROUND/AIMS: To improve understanding of patients' experience and perception of dry eye disease (DED) and its impact on quality of life (QoL). METHODS: This survey was observational, non-interventional and cross-sectional. The survey was conducted online on 706 patients with DED from five European countries (France, Germany, Italy, Spain and the UK). All patients met the following inclusion criteria: 40 years or older with DED diagnosed by a healthcare professional (HCP), not wearing contact lenses and using tear substitutes daily for at least 6 months. The survey (performed in the five native languages) included 9 screening questions (inclusion criteria) and 26 complementary questions about patients' demography, disease history, DED diagnosis, use of relief treatments, perceptions of DED condition and its impact on QoL. RESULTS: Overall, 218 of 706 (31%) patients perceived DED as a 'disease' or even a 'handicap', and 468 of 706 (66%) as a 'discomfort'. High impact of DED on patients' QoL was associated with negative perception, delay in diagnosis, visits to more than one HCP before diagnosis and high frequency of treatment use. This survey also provided us with a list of language-specific keywords that patients used most frequently to spontaneously describe their condition. CONCLUSIONS: Findings showed that negative perception of DED, delayed diagnosis and high frequency of treatment use were inter-related, and that all have a negative impact on patients' QoL. The generated language-specific keywords used to describe DED could serve as the basis for a comprehensive QoL questionnaire to be used in clinical settings. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
Entities:
Keywords:
Ocular surface; Tears; Treatment Medical
Authors: Gemma Caterina Maria Rossi; Luigia Scudeller; Federica Bettio; Gian Maria Pasinetti; Paolo Emilio Bianchi Journal: Int Ophthalmol Date: 2018-06-07 Impact factor: 2.031
Authors: Andrea Leonardi; Elisabeth M Messmer; Marc Labetoulle; Mourad Amrane; Jean-Sébastien Garrigue; Dahlia Ismail; Maite Sainz-de-la-Maza; Francisco C Figueiredo; Christophe Baudouin Journal: Br J Ophthalmol Date: 2018-03-15 Impact factor: 4.638
Authors: Olga Husson; Winette Ta van der Graaf; Vicky Soomers; Ingrid Me Desar; Lonneke V van de Poll-Franse Journal: BMJ Open Date: 2020-10-26 Impact factor: 2.692