Literature DB >> 28000905

Teratomas produced from human pluripotent stem cells xenografted into immunodeficient mice - a histopathology atlas.

Ivan Damjanov1, Peter W Andrews.   

Abstract

This atlas illustrates the microscopic features of tumors produced from human pluripotent stem cells (hPSCs) xenografted into immunosuppressed mice, according to the generally accepted protocols for performing this teratoma assay of stem cell pluripotency. Microphotographs depict various hematoxylin and eosin (H&E) stained tissues derived from all three embryonic germ layers (ectoderm, mesoderm and endoderm). The appearance of persistent hPSC in teratomas is also described with special emphasis on the morphogenesis of embryoid bodies and yolk sac components surrounding them. The use of immunohistochemistry for analyzing hPSC-derived teratomas is also illustrated.

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Mesh：

Year:  2016        PMID： 28000905      PMCID： PMC5338735          DOI： 10.1387/ijdb.160274id

Source DB:  PubMed          Journal:  Int J Dev Biol        ISSN： 0214-6282            Impact factor:   2.203


  21 in total

1.  MULTIPOTENTIALITY OF SINGLE EMBRYONAL CARCINOMA CELLS.

Authors:  L J KLEINSMITH; G B PIERCE
Journal:  Cancer Res       Date:  1964-10       Impact factor: 12.701

2.  The terminology of teratocarcinomas and teratomas.

Authors:  Ivan Damjanov; Peter W Andrews
Journal:  Nat Biotechnol       Date:  2007-11       Impact factor: 54.908

Review 3.  Concise Review: Manufacturing of Pancreatic Endoderm Cells for Clinical Trials in Type 1 Diabetes.

Authors:  Thomas C Schulz
Journal:  Stem Cells Transl Med       Date:  2015-06-10       Impact factor: 6.940

4.  Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.

Authors:  Katherine Amps; Peter W Andrews; George Anyfantis; Lyle Armstrong; Stuart Avery; Hossein Baharvand; Julie Baker; Duncan Baker; Maria B Munoz; Stephen Beil; Nissim Benvenisty; Dalit Ben-Yosef; Juan-Carlos Biancotti; Alexis Bosman; Romulo Martin Brena; Daniel Brison; Gunilla Caisander; María V Camarasa; Jieming Chen; Eric Chiao; Young Min Choi; Andre B H Choo; Daniel Collins; Alan Colman; Jeremy M Crook; George Q Daley; Anne Dalton; Paul A De Sousa; Chris Denning; Janet Downie; Petr Dvorak; Karen D Montgomery; Anis Feki; Angela Ford; Victoria Fox; Ana M Fraga; Tzvia Frumkin; Lin Ge; Paul J Gokhale; Tamar Golan-Lev; Hamid Gourabi; Michal Gropp; Guangxiu Lu; Ales Hampl; Katie Harron; Lyn Healy; Wishva Herath; Frida Holm; Outi Hovatta; Johan Hyllner; Maneesha S Inamdar; Astrid Kresentia Irwanto; Tetsuya Ishii; Marisa Jaconi; Ying Jin; Susan Kimber; Sergey Kiselev; Barbara B Knowles; Oded Kopper; Valeri Kukharenko; Anver Kuliev; Maria A Lagarkova; Peter W Laird; Majlinda Lako; Andrew L Laslett; Neta Lavon; Dong Ryul Lee; Jeoung Eun Lee; Chunliang Li; Linda S Lim; Tenneille E Ludwig; Yu Ma; Edna Maltby; Ileana Mateizel; Yoav Mayshar; Maria Mileikovsky; Stephen L Minger; Takamichi Miyazaki; Shin Yong Moon; Harry Moore; Christine Mummery; Andras Nagy; Norio Nakatsuji; Kavita Narwani; Steve K W Oh; Sun Kyung Oh; Cia Olson; Timo Otonkoski; Fei Pan; In-Hyun Park; Steve Pells; Martin F Pera; Lygia V Pereira; Ouyang Qi; Grace Selva Raj; Benjamin Reubinoff; Alan Robins; Paul Robson; Janet Rossant; Ghasem H Salekdeh; Thomas C Schulz; Karen Sermon; Jameelah Sheik Mohamed; Hui Shen; Eric Sherrer; Kuldip Sidhu; Shirani Sivarajah; Heli Skottman; Claudia Spits; Glyn N Stacey; Raimund Strehl; Nick Strelchenko; Hirofumi Suemori; Bowen Sun; Riitta Suuronen; Kazutoshi Takahashi; Timo Tuuri; Parvathy Venu; Yuri Verlinsky; Dorien Ward-van Oostwaard; Daniel J Weisenberger; Yue Wu; Shinya Yamanaka; Lorraine Young; Qi Zhou
Journal:  Nat Biotechnol       Date:  2011-11-27       Impact factor: 54.908

Review 5.  Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: opposite sides of the same coin.

Authors:  P W Andrews; M M Matin; A R Bahrami; I Damjanov; P Gokhale; J S Draper
Journal:  Biochem Soc Trans       Date:  2005-12       Impact factor: 5.407

6.  Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Authors:  Kazutoshi Takahashi; Shinya Yamanaka
Journal:  Cell       Date:  2006-08-10       Impact factor: 41.582

7.  Embryonic stem cell lines derived from human blastocysts.

Authors:  J A Thomson; J Itskovitz-Eldor; S S Shapiro; M A Waknitz; J J Swiergiel; V S Marshall; J M Jones
Journal:  Science       Date:  1998-11-06       Impact factor: 47.728

8.  Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro.

Authors:  P W Andrews; I Damjanov; D Simon; G S Banting; C Carlin; N C Dracopoli; J Føgh
Journal:  Lab Invest       Date:  1984-02       Impact factor: 5.662

Review 9.  Testicular germ cell tumors and related research from a historical point of view.

Authors:  Ivan Damjanov; Nicolai Wewer-Albrechtsen
Journal:  Int J Dev Biol       Date:  2013       Impact factor: 2.203

10.  Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.

Authors:  Oluseun Adewumi; Behrouz Aflatoonian; Lars Ahrlund-Richter; Michal Amit; Peter W Andrews; Gemma Beighton; Paul A Bello; Nissim Benvenisty; Lorraine S Berry; Simon Bevan; Barak Blum; Justin Brooking; Kevin G Chen; Andre B H Choo; Gary A Churchill; Marie Corbel; Ivan Damjanov; Jon S Draper; Petr Dvorak; Katarina Emanuelsson; Roland A Fleck; Angela Ford; Karin Gertow; Marina Gertsenstein; Paul J Gokhale; Rebecca S Hamilton; Ales Hampl; Lyn E Healy; Outi Hovatta; Johan Hyllner; Marta P Imreh; Joseph Itskovitz-Eldor; Jamie Jackson; Jacqueline L Johnson; Mark Jones; Kehkooi Kee; Benjamin L King; Barbara B Knowles; Majlinda Lako; Franck Lebrin; Barbara S Mallon; Daisy Manning; Yoav Mayshar; Ronald D G McKay; Anna E Michalska; Milla Mikkola; Masha Mileikovsky; Stephen L Minger; Harry D Moore; Christine L Mummery; Andras Nagy; Norio Nakatsuji; Carmel M O'Brien; Steve K W Oh; Cia Olsson; Timo Otonkoski; Kye-Yoon Park; Robert Passier; Hema Patel; Minal Patel; Roger Pedersen; Martin F Pera; Marian S Piekarczyk; Renee A Reijo Pera; Benjamin E Reubinoff; Allan J Robins; Janet Rossant; Peter Rugg-Gunn; Thomas C Schulz; Henrik Semb; Eric S Sherrer; Henrike Siemen; Glyn N Stacey; Miodrag Stojkovic; Hirofumi Suemori; Jin Szatkiewicz; Tikva Turetsky; Timo Tuuri; Steineke van den Brink; Kristina Vintersten; Sanna Vuoristo; Dorien Ward; Thomas A Weaver; Lesley A Young; Weidong Zhang
Journal:  Nat Biotechnol       Date:  2007-06-17       Impact factor: 54.908
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  16 in total

Review 1.  Human pluripotent stem cells: tools for regenerative medicine.

Authors:  Peter W Andrews
Journal:  Biomater Transl       Date:  2021-12-28

Review 2.  Acquired genetic changes in human pluripotent stem cells: origins and consequences.

Authors:  Jason Halliwell; Ivana Barbaric; Peter W Andrews
Journal:  Nat Rev Mol Cell Biol       Date:  2020-09-23       Impact factor: 94.444

3.  Sand-mediated ice seeding enables serum-free low-cryoprotectant cryopreservation of human induced pluripotent stem cells.

Authors:  Bin Jiang; Weijie Li; Samantha Stewart; Wenquan Ou; Baolin Liu; Pierre Comizzoli; Xiaoming He
Journal:  Bioact Mater       Date:  2021-04-30

4.  The MicroRNA-371 Family as Plasma Biomarkers for Monitoring Undifferentiated and Potentially Malignant Human Pluripotent Stem Cells in Teratoma Assays.

Authors:  Daniela C F Salvatori; Lambert C J Dorssers; Ad J M Gillis; Gemma Perretta; Ton van Agthoven; Maria Gomes Fernandes; Hans Stoop; Jan-Bas Prins; J Wolter Oosterhuis; Christine Mummery; Leendert H J Looijenga
Journal:  Stem Cell Reports       Date:  2018-11-29       Impact factor: 7.765

5.  Establishment of porcine nuclear transfer-derived embryonic stem cells using induced pluripotent stem cells as donor nuclei.

Authors:  Seiki Haraguchi; Thanh Quang Dang-Nguyen; David Wells; Daiichiro Fuchimoto; Tomokazu Fukuda; Tomoyuki Tokunaga
Journal:  J Reprod Dev       Date:  2020-01-26       Impact factor: 2.214

Review 6.  Evidence for immortality and autonomy in animal cancer models is often not provided, which causes confusion on key issues of cancer biology.

Authors:  Xixi Dou; Pingzhen Tong; Hai Huang; Lucas Zellmer; Yan He; Qingwen Jia; Daizhou Zhang; Jiang Peng; Chenguang Wang; Ningzhi Xu; Dezhong Joshua Liao
Journal:  J Cancer       Date:  2020-03-04       Impact factor: 4.207

7.  Embryo-derived teratoma in vitro biological system reveals antitumor and embryotoxic activity of valproate.

Authors:  Milvija Plazibat; Ana Katušić Bojanac; Marta Himerleich Perić; Ozren Gamulin; Mario Rašić; Vedran Radonić; Marko Škrabić; Maria Krajačić; Jure Krasić; Nino Sinčić; Gordana Jurić-Lekić; Maja Balarin; Floriana Bulić-Jakuš
Journal:  FEBS J       Date:  2020-02-28       Impact factor: 5.542

8.  Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells.

Authors: 
Journal:  Nat Commun       Date:  2018-05-15       Impact factor: 14.919

9.  Tumorigenicity-associated characteristics of human iPS cell lines.

Authors:  Satoshi Yasuda; Shinji Kusakawa; Takuya Kuroda; Takumi Miura; Keiko Tano; Nozomi Takada; Satoko Matsuyama; Akifumi Matsuyama; Michiyo Nasu; Akihiro Umezawa; Takao Hayakawa; Hideki Tsutsumi; Yoji Sato
Journal:  PLoS One       Date:  2018-10-04       Impact factor: 3.240

10.  Human Teratoma-Derived Hematopoiesis Is a Highly Polyclonal Process Supported by Human Umbilical Vein Endothelial Cells.

Authors:  Friederike Philipp; Anton Selich; Michael Rothe; Dirk Hoffmann; Susanne Rittinghausen; Michael A Morgan; Denise Klatt; Silke Glage; Stefan Lienenklaus; Vanessa Neuhaus; Katherina Sewald; Armin Braun; Axel Schambach
Journal:  Stem Cell Reports       Date:  2018-10-18       Impact factor: 7.765
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