| Literature DB >> 27998963 |
I S Batth1, A Mitra1, S Manier2, I M Ghobrial2, D Menter3, S Kopetz3, S Li1.
Abstract
Current trajectory of clinical care is heading in the direction of personalized medicine. In an ideal scenario, clinicians can obtain extensive diagnostic and prognostic information via minimally-invasive assays. Information available in the peripheral blood has the potential to bring us closer to this goal. In this review we highlight the contributions of circulating tumor cells and circulating tumor DNA and RNA (ctDNA/ctRNA) towards cancer therapeutic field. We discuss clinical relevance, summarize available and upcoming technologies, and hypothesize how future care could be impacted by a combined study.Entities:
Keywords: cell free DNA; cell free RNA; circulating tumor DNA; circulating tumor RNA; circulating tumor cells; exosomes
Mesh:
Substances:
Year: 2017 PMID: 27998963 PMCID: PMC6246190 DOI: 10.1093/annonc/mdw619
Source DB: PubMed Journal: Ann Oncol ISSN: 0923-7534 Impact factor: 32.976